Tetracaine
- tetracaine
- 94-24-6
- Amethocaine
- 2-(Dimethylamino)ethyl 4-(butylamino)benzoate
- Pontocaine
- Create:2005-03-25
- Modify:2025-01-18
- Amethocaine
- Ametop
- Dicaine
- Hydrochloride, Tetrracaine
- Pantocaine
- Pontocaine
- Tetracaine
- Tetracaine Monohydrochloride
- Tetrakain
- Tetrracaine Hydrochloride
- tetracaine
- 94-24-6
- Amethocaine
- 2-(Dimethylamino)ethyl 4-(butylamino)benzoate
- Pontocaine
- Dicaine
- Laudocaine
- Metraspray
- Tetracaina
- Tetrakain
- Anetain
- Uromucaesthin
- Contralgin
- Fissucain
- Intercain
- Meethobalm
- Mucaesthin
- Rexocaine
- Tetracainum
- Dicain
- Medihaler-Tetracaine
- Medicaine
- Niphanoid
- Dikain
- 2-(Dimethylamino)ethyl p-(butylamino)benzoate
- p-Butylaminobenzoyl-2-dimethylaminoethanol
- Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester
- Diaethylaminoaethanol ester der p-butylaminobenzoesaeure
- Tetracainum [INN-Latin]
- Dimethylaminoethyl p-butyl-aminobenzoate
- Tetracaina [INN-Spanish]
- CHEBI:9468
- Amethocaine HCl
- EINECS 202-316-6
- MFCD00053787
- 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester
- p-(Butylamino)benzoic acid, 2-(dimethylamino)ethyl ester
- UNII-0619F35CGV
- BRN 2216051
- BENZOIC ACID, p-(BUTYLAMINO)-, 2-(DIMETHYLAMINO)ETHYL ESTER
- 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove
- 0619F35CGV
- CHEMBL698
- Tetracaine [USP:INN:BAN]
- DTXSID1043883
- Tetracaine Base
- SYNERA COMPONENT TETRACAINE
- 4-14-00-01172 (Beilstein Handbook Reference)
- Tetrakain [Czech]
- p-(butylamino)benzoic acid beta-(dimethylamino)ethyl ester
- Tetracainum (INN-Latin)
- Tetracaina (INN-Spanish)
- TETRACAINE (MART.)
- TETRACAINE [MART.]
- TETRACAINE (USP-RS)
- TETRACAINE [USP-RS]
- Tetracaine (USP:INN:BAN)
- TETRACAINE (EP MONOGRAPH)
- TETRACAINE [EP MONOGRAPH]
- TETRACAINE (USP MONOGRAPH)
- TETRACAINE [USP MONOGRAPH]
- 100311-22-6
- Amethocaine (TN)
- Tetracaine (USP/INN)
- NCGC00016049-02
- CAS-136-47-0
- Landocaine
- Tetracain
- Tetracaine cream
- 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove [Czech]
- FranklyNumb 3
- Diaethylaminoaethanol ester der p-butylaminobenzoesaeure [German]
- TE4
- Burn Solution Cream
- Spectrum_001032
- Pantocaine (Salt/Mix)
- Numfast Tetracaine Green
- TETRACAINE [INN]
- Prestwick0_000571
- Prestwick1_000571
- Prestwick2_000571
- Prestwick3_000571
- Spectrum2_001328
- Spectrum3_000562
- Spectrum4_000351
- Spectrum5_001072
- Lopac-T-7508
- TETRACAINE [VANDF]
- Epitope ID:174843
- BLT 3
- TETRACAINE [WHO-DD]
- Lopac0_001211
- SCHEMBL34714
- BSPBio_000382
- BSPBio_001944
- KBioGR_000781
- KBioSS_001512
- DivK1c_000607
- SPBio_001455
- SPBio_002601
- BPBio1_000422
- TETRACAINE [GREEN BOOK]
- Tetracaine, >=98% (TLC)
- DTXCID9023883
- TETRACAINE [ORANGE BOOK]
- KBio1_000607
- KBio2_001512
- KBio2_004080
- KBio2_006648
- KBio3_001444
- C05AD02
- D04AB06
- N01BA03
- S01HA03
- NINDS_000607
- BCPP000048
- ALBB-025902
- BCP04777
- HY-A0079
- BDBM50017659
- STL483844
- TETRACAINE COMPONENT OF SYNERA
- AKOS015889234
- AC-3480
- CCG-205285
- DB09085
- SDCCGSBI-0051178.P005
- IDI1_000607
- NCGC00016049-01
- NCGC00016049-03
- NCGC00016049-04
- NCGC00016049-14
- NCGC00162367-01
- AS-81743
- DA-78348
- SY066710
- BCP0726000001
- SBI-0051178.P004
- AB00053549
- NS00008930
- T2789
- Tetracaine, meets USP testing specifications
- .beta.-Dimethylaminoethyl p-butylaminobenzoate
- C07526
- D00551
- 2-(Dimethylamino)ethyl 4-(butylamino)benzoate #
- AB00053549-11
- AB00053549_12
- AB00053549_13
- EN300-6748839
- Q419608
- aniline, N-butyl-4-(2-dimethylaminoethoxycarbonyl)-
- Diathylaminoathanol ester der p-butylaminobenzosaure
- Q-201805
- BRD-K45071273-003-05-8
- BRD-K45071273-003-15-7
- BRD-K45071273-003-24-9
- BRD-K45071273-003-25-6
- Tetracaine, United States Pharmacopeia (USP) Reference Standard
- benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester ,hydrochloride
- BENZOIC ACID,4-BUTYLAMINO,2-DIMETHYLAMINOETHYL ESTER PANTOCAIN BASE
- InChI=1/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H
158.41 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
164.78 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
170.85 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
176.106 100
120.0436 25.89
177.1091 10.40
118.0643 6.15
148.1108 3.39
176.1062 100
177.1092 12.11
120.0437 8.78
148.1109 2.16
220.1321 1.90
265.1914 999
176.1064 952
266.1941 183
177.1094 118
220.1327 54
176.107 999
220.1327 155
221.1356 21
178.1118 11
265.1903 9
- Tetracaine Hydrochloride (has salt form)
- Lidocaine; Tetracaine (component of)
- Benzocaine; Lidocaine; Tetracaine (component of)
- Lidocaine; tetracaine; witch hazel (component of)
N - Nervous system
N01 - Anesthetics
N01B - Anesthetics, local
N01BA - Esters of aminobenzoic acid
N01BA03 - Tetracaine
S - Sensory organs
S01 - Ophthalmologicals
S01H - Local anesthetics
S01HA - Local anesthetics
S01HA03 - Tetracaine
Use (kg; approx.) in Germany (2009): >50
Consumption (g per capita; approx.) in Germany (2009): 0.000611
Calculated removal (%): 44.3
H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]
H317 (92.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H351 (92.9%): Suspected of causing cancer [Warning Carcinogenicity]
P203, P261, P264, P270, P272, P280, P301+P316, P302+P352, P318, P321, P330, P333+P317, P362+P364, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 42 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 3 (97.6%)
Skin Sens. 1 (92.9%)
Carc. 2 (92.9%)
IMAP assessments - Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester: Environment tier I assessment
IMAP assessments - Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester: Human health tier I assessment
◉ Summary of Use during Lactation
No information is available on the use of tetracaine during breastfeeding. Based on the low excretion of other local anesthetics into breastmilk, a single dose of injected tetracaine during breastfeeding, such as for a dental procedure, is unlikely to adversely affect the breastfed infant. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Topical application of tetracaine to the mother is unlikely to affect her breastfed infant if it is applied away from the breast. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.
◉ Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=GKCBAIGFKIBETG-UHFFFAOYSA-N
- Australian Industrial Chemicals Introduction Scheme (AICIS)Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl esterhttps://services.industrialchemicals.gov.au/search-assessments/
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- ChemIDplusTetracaine [USP:INN:BAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0000094246ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_useTetracainehttps://www.drugbank.ca/drugs/DB09085
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- ChEBI
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- IUPAC Digitized pKa Datasetaniline, N-butyl-4-(2-dimethylaminoethoxycarbonyl)-https://github.com/IUPAC/Dissociation-Constants
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- Therapeutic Target Database (TTD)
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- Metabolomics Workbench
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- SpectraBase4-Butylamino-benzoic acid, 2-dimethylamino-ethyl esterhttps://spectrabase.com/spectrum/8ChMOwW8iPZTETRACAINE HYDROCHLORIDE U.S.P.https://spectrabase.com/spectrum/32CN4mbDBpO
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- Springer Nature
- SpringerMaterialsBenzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl esterhttps://materials.springer.com/substanceprofile/docs/smsid_ikqgjwlotdzebqxe
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- Wikidatatetracainehttps://www.wikidata.org/wiki/Q419608
- WikipediaOxybuprocainehttps://en.wikipedia.org/wiki/OxybuprocaineTetracainehttps://en.wikipedia.org/wiki/Tetracaine
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