Tegafur
- tegafur
- 17902-23-7
- Ftorafur
- Futraful
- Sinoflurol
- Create:2005-03-25
- Modify:2025-01-18
- 1-(2-Tetrahydrofuryl)-5-fluorouracil
- 1-(Tetrahydro-2-furanyl)-5-fluorouracil
- 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
- Florafur
- Fluorofur
- FT 207
- FT-207
- FT207
- Ftorafur
- Futraful
- N1-(2'-Tetrahydrofuryl)-5-fluorouracil
- Sunfural S
- Tegafur
- Uftoral
- Utefos
- tegafur
- 17902-23-7
- Ftorafur
- Futraful
- Sinoflurol
- Fental
- Fluorofur
- Citofur
- Neberk
- Coparogin
- Furafluor
- Furofutran
- Nitobanil
- Exonal
- Fulfeel
- Lifril
- Lamar
- Tefsiel C
- Florafur
- Riol
- 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
- Franroze
- Furflucil
- Sunfral
- 5-Fluoro-1-(tetrahydro-2-furyl)uracil
- FT-207
- 1-(2-Tetrahydrofuryl)-5-fluorouracil
- Franrose
- Phthorafur
- Sunfural
- Fulaid
- MJF-12264
- 5-FLUORO-1-(TETRAHYDRO-2-FURFURYL)URACIL
- 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
- 5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
- Atillon
- NSC-148958
- URACIL, 5-FLUORO-1-(TETRAHYDRO-2-FURYL)-
- MFCD00012351
- 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
- N1-(2-tetrahydrofuryl)-5-fluorouracil
- 1-(Tetrahydrofuran-2-yl)-5-fluorouracil
- 5-Fluoro-1-(tetrahydrofuran-2-yl)uracil
- FT-207 (NSC 148958)
- Uracil, 1-(tetrahydrofuran-2-yl)-5-fluoro-
- FT 207
- 5-Fluoro-1-(tetrahydro-3-furyl)uracil
- 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione
- MLS000069497
- CHEBI:32188
- 1548R74NSZ
- 5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione
- SMR000059106
- 2,4(1H,3H)Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
- 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
- Racemic Ftorafur
- 82294-77-7
- Phthorafur [Czech]
- C8H9FN2O3
- Fluorafur
- Tegafurum
- Tegafurum [INN-Latin]
- NSC 148958
- CCRIS 2762
- FT207
- EINECS 241-846-2
- BRN 0525766
- N1-(2'-Tetrahydrofuryl)-5-fluorouracil
- UNII-1548R74NSZ
- Tegafur?
- N(sub 1)-(2-Tetrahydrofuryl)-5-fluorouracil
- Tegafur [USAN:INN:BAN:JAN]
- 1-(2-TETRAHYDROFORMYL)-5-FLUOROURACIL
- N(sub 1)-(2'-Furanidyl)-5-fluouracil [Czech]
- NCGC00159418-02
- NCGC00159418-05
- Atillon (TN)
- Tegafur (Standard)
- Tegafur ,(S)
- S-1 component tegafur
- N(sub 1)-(2'-Furanidyl)-5-fluouracil
- TS-1 (Salt/Mix)
- TS-1 component tegafur
- TEGAFUR [USAN]
- TEGAFUR [INN]
- TEGAFUR [JAN]
- TEGAFUR [MI]
- Opera_ID_1726
- TEGAFUR [MART.]
- TEGAFUR [WHO-DD]
- UPCMLD-DP063
- SCHEMBL4552
- TEGAFUR [EMA EPAR]
- 5-24-06-00285 (Beilstein Handbook Reference)
- MLS000759414
- MLS001076521
- MLS001424119
- CHEMBL20883
- Tegafur (JP18/USAN/INN)
- F-5-FU
- TEYSUNO COMPONENT TEGAFUR
- 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[(2R)-tetrahydro-2-furanyl]-
- UPCMLD-DP063:001
- GTPL10513
- DTXSID001009966
- HMS1665I05
- HMS2051B15
- HMS2090K04
- HMS2232E05
- HMS3371H21
- HMS3393B15
- HMS3654P13
- HMS3715D14
- N1-(2'-Furanidyl)-5-fluouracil
- 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
- BCP22714
- 5-fluoro-1-(tetrahydrofuran-2-yl)
- N1-(2'-Furanidyl)-5-fluorouracil
- BBL027795
- CCG-50110
- HY-17400R
- STK528044
- Tegafur, >=98% (HPLC), powder
- 5-Fluoro-1-(2-tetrahydrofuryl)uracil
- AKOS000121279
- AC-2112
- CCG-100959
- CS-1128
- DB09256
- NC00209
- 1-(tetrahydro-2-furyl)-5-fluorouracil
- 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, didehydroderiv.
- 5-fluoro-1-(2-tetrahydrofuranyl)uracil
- 5-fluoro-1-(tetrahydro-2-furyl)-uracil
- N1 -(2-tetrahydrofuryl)-5-fluorouracil
- NCGC00159418-04
- AS-13528
- BP-58663
- HY-17400
- Tegafur (FT-207; NSC 148958)
- NS00007105
- EN300-21668
- D01244
- AB00572620-15
- Q413370
- SR-01000639511
- Q-201784
- SR-01000639511-1
- SR-01000639511-4
- Z104508106
- 5-fluoro-1-tetrahydro-furan-2-yl-1H-pyrimidine-2,4-dione
- pyrimidine-2,4(1H,3H)-dione, 5-fluoro-1-(2-oxolanyl)-
- 5-Fluoro-1-tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione
- 2, 4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, (R)-
71.0 99.99
43.0 40
200.0 22
41.0 21
72.0 14
131.0 99.99
71.0 82
202.0 8
132.0 7
201.0 0.65
131.02361 100
71.05368 75
113.99843 50
71.04895 25
131.02361 100
71.05368 75
113.99843 50
71.04895 25
113.98944 25
71 999
43 400
200 220
41 210
72 140
131 999
71 820
202 80
132 70
201 7
H301 (95.1%): Toxic if swallowed [Danger Acute toxicity, oral]
H311 (95.1%): Toxic in contact with skin [Danger Acute toxicity, dermal]
H331 (95.1%): Toxic if inhaled [Danger Acute toxicity, inhalation]
P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P304+P340, P316, P321, P330, P361+P364, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 3 (95.1%)
Acute Tox. 3 (95.1%)
Acute Tox. 3 (95.1%)
IMAP assessments - 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-: Environment tier I assessment
IMAP assessments - 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-: Human health tier I assessment
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=WFWLQNSHRPWKFK-UHFFFAOYSA-N
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=CRUWQVXYAQRELW-UHFFFAOYSA-N
- Drink plenty of fluids. Drinking water is important to prevent dehydration when taking Teysuno.
- Take on an empty stomach. Food does not impact the bioavailability of tegafur. Food does affect other ingredients in the combination product Teysuno. Take Teysuno at least 1 hour before or after eating.
- Australian Industrial Chemicals Introduction Scheme (AICIS)2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-https://services.industrialchemicals.gov.au/search-assessments/
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/
- ChemIDplusTegafur [USAN:INN:BAN:JAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=00179022372,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, didehydroderiv.https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0082294777ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_use
- EPA Chemicals under the TSCA2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-https://www.epa.gov/chemicals-under-tscaEPA TSCA Classificationhttps://www.epa.gov/tsca-inventory
- EPA DSSToxCompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice5-fluoro-1-(tetrahydro-2-furyl)uracilhttps://echa.europa.eu/substance-information/-/substanceinfo/100.038.0275-fluoro-1-(tetrahydro-2-furyl)uracil (EC: 241-846-2)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/18923
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- Burnham Center for Chemical Genomics
- ChEBI
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuseNCI Thesaurushttps://ncit.nci.nih.gov
- Open TargetsLICENSEDatasets generated by the Open Targets Platform are freely available for download.https://platform-docs.opentargets.org/licence
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.htmlChEMBL Protein Target Treehttps://www.ebi.ac.uk/chembl/g/#browse/targets
- Comparative Toxicogenomics Database (CTD)LICENSEIt is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.http://ctdbase.org/about/legal.jsp
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- Therapeutic Target Database (TTD)
- NORMAN Suspect List ExchangeLICENSEData: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0https://creativecommons.org/licenses/by/4.0/TegafurNORMAN Suspect List Exchange Classificationhttps://www.norman-network.com/nds/SLE/
- EU Clinical Trials Register
- Human Metabolome Database (HMDB)LICENSEHMDB is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (HMDB) and the original publication (see the HMDB citing page). We ask that users who download significant portions of the database cite the HMDB paper in any resulting publications.http://www.hmdb.ca/citing2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, (R)-http://www.hmdb.ca/metabolites/HMDB0246215HMDB0246215_cms_27933https://hmdb.ca/metabolites/HMDB0246215#spectra
- MassBank of North America (MoNA)LICENSEThe content of the MoNA database is licensed under CC BY 4.0.https://mona.fiehnlab.ucdavis.edu/documentation/license
- NIST Mass Spectrometry Data CenterLICENSEData covered by the Standard Reference Data Act of 1968 as amended.https://www.nist.gov/srd/public-law
- SpectraBase1-(Tetrahydro-2-furanyl)-5-fluorouracilhttps://spectrabase.com/spectrum/JrTNPYUglxw2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-https://spectrabase.com/spectrum/Z3sOIXqD8I5-fluoro-1-(tetrahydro-2-furyl)uracilhttps://spectrabase.com/spectrum/1YPJoibv32gFtorafur (5-fluoro-1-(tetrahydro-2-furyl)uracil)https://spectrabase.com/spectrum/7aaw7lqJsid5-FLUORO-1-(TETRAHYDRO-2-FURYL)URACILhttps://spectrabase.com/spectrum/JZLl29dXlTDFtorafur (5-fluoro-1-(tetrahydro-2-furyl)uracil)https://spectrabase.com/spectrum/ElZtu0jyNRS5-fluoro-1-(tetrahydro-2-furyl)uracilhttps://spectrabase.com/spectrum/ElSboHq80CiFtorafur (5-fluoro-1-(tetrahydro-2-furyl)uracil)https://spectrabase.com/spectrum/4f2q9EXFf8uFtorafur (5-fluoro-1-(tetrahydro-2-furyl)uracil)https://spectrabase.com/spectrum/2szY0czk9yxFtorafur (5-fluoro-1-(tetrahydro-2-furyl)uracil)https://spectrabase.com/spectrum/BkLTL0puIk1
- IUPAC Digitized pKa Datasetpyrimidine-2,4(1H,3H)-dione, 5-fluoro-1-(2-oxolanyl)-https://github.com/IUPAC/Dissociation-Constants
- Japan Chemical Substance Dictionary (Nikkaji)
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.htmlAnatomical Therapeutic Chemical (ATC) classificationhttp://www.genome.jp/kegg-bin/get_htext?br08303.kegTarget-based classification of drugshttp://www.genome.jp/kegg-bin/get_htext?br08310.kegDrugs listed in the Japanese Pharmacopoeiahttp://www.genome.jp/kegg-bin/get_htext?br08311.keg
- MassBank Europe1-(TETRAHYDRO-2-FURANYL)-5-FLUOROURACILhttps://massbank.eu/MassBank/Result.jsp?inchikey=WFWLQNSHRPWKFK-UHFFFAOYSA-N
- Metabolomics Workbench
- NIPH Clinical Trials Search of Japan
- WHO Anatomical Therapeutic Chemical (ATC) ClassificationLICENSEUse of all or parts of the material requires reference to the WHO Collaborating Centre for Drug Statistics Methodology. Copying and distribution for commercial purposes is not allowed. Changing or manipulating the material is not allowed.https://www.whocc.no/copyright_disclaimer/
- PharmGKBLICENSEPharmGKB data are subject to the Creative Commons Attribution-ShareALike 4.0 license (https://creativecommons.org/licenses/by-sa/4.0/).https://www.pharmgkb.org/page/policies
- Springer Nature
- Thieme ChemistryLICENSEThe Thieme Chemistry contribution within PubChem is provided under a CC-BY-NC-ND 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc-nd/4.0/
- Wikidata(RS)-tegafurhttps://www.wikidata.org/wiki/Q413370
- WikipediaChlormadinonehttps://en.wikipedia.org/wiki/Chlormadinone
- Wiley
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlAntimetabolites, Antineoplastichttps://www.ncbi.nlm.nih.gov/mesh/68000964
- PubChemPFAS and Fluorinated Compounds in PubChemhttps://gitlab.com/uniluxembourg/lcsb/eci/pubchem-docs/-/raw/main/pfas-tree/PFAS_Tree.pdf?inline=false
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- EPA Substance Registry ServicesEPA SRS List Classificationhttps://sor.epa.gov/sor_internet/registry/substreg/LandingPage.do
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 403454043https://pubchem.ncbi.nlm.nih.gov/substance/403454043SID 404141049https://pubchem.ncbi.nlm.nih.gov/substance/404141049