Amitrole
- Amitrole
- 3-amino-1,2,4-triazole
- 61-82-5
- 4H-1,2,4-triazol-3-amine
- 1H-1,2,4-Triazol-5-amine
- Create:2004-09-16
- Modify:2025-01-18
- 3-Amino-1,2,4-triazole
- Aminotriazole
- Amitrole
- Amitrole
- 3-amino-1,2,4-triazole
- 61-82-5
- 4H-1,2,4-triazol-3-amine
- 1H-1,2,4-Triazol-5-amine
- 1H-1,2,4-Triazol-3-amine
- Aminotriazole
- 65312-61-0
- 3-Aminotriazole
- Amitrol
- 3-Amino-1H-1,2,4-triazole
- Amizol
- 3-Amino-s-triazole
- 65380-04-3
- Weedazol
- Cytrol
- Emisol
- Vorox
- (4H)-1,2,4-Triazol-3-amine
- Amitolamitril
- Triazolamine
- Azaplant
- Cytrole
- Elmasil
- Fenavar
- Herbizole
- Ramizol
- Weedazin
- Weedoclor
- Azolan
- Weedex granulat
- Azaplant kombi
- Herbidal total
- Weedazol super
- Weedazin arginit
- Weedazol T
- Amizol dp nau
- Amitrol-T
- Kleer-Lot
- Radoxone TL
- x-all Liquid
- Amizol D
- Amizol F
- Emisol F
- Weedar AT
- 3-AT
- Weedar ADS
- Weedazol GP2
- Vorox AA
- Vorox AS
- Amitrol 90
- Emisol 50
- Usaf xr-22
- Campaprim A 1544
- Diurol 5030
- Aminotriazol-spritzpulver
- 2H-[1,2,4]Triazol-3-ylamine
- Orga-414
- 2-AMINO-1,3,4-TRIAZOLE
- Amitril T.L.
- 5-Amino-1H-1,2,4-triazole
- 1H-1,2,4-Triazol-3-ylamine
- 3H-1,2,4-Triazol-3-imine, 2,4-dihydro-
- s-Triazole, 3-amino-
- Aminotriazole (plant regulator)
- ENT 25445
- 1,2,4-Triazol-3-amine
- Domatol 88
- 1H-1,2,4-Triazole-3-amine
- 1H-[1,2,4]Triazol-3-ylamine
- ZF80H5GXUF
- 5-amino-1,2,4-triazole
- CHEMBL232801
- 1,2,4-Triazole, 3-amino-
- 155-25-9
- DTXSID0020076
- CHEBI:40036
- NSC7243
- NSC-34809
- 3-Amino-1,2,4-triazole (Amitrole)
- Simazol
- Trapidil EP impurity B
- Diurol
- 3-Amino-1,4-triazol
- 2-Amino-1,4-triazole
- 3-Amino-1,4-triazole
- WLN: T5MN DNJ CZ
- DTXCID9076
- 1H-1,4-Triazol-3-amine
- 218787-12-3
- 3-Amino-1H-1,4-triazole
- 5-Amino-1H-1,4-triazole
- Caswell No. 040
- Maxata
- RCRA waste number U011
- CAS-61-82-5
- CCRIS 40
- .DELTA.2-1,4-Triazoline, 5-imino-
- Amitrole [ANSI:BSI:ISO]
- Amitrole [ISO]
- Amino triazole weedkiller 90
- HSDB 2953
- EINECS 200-521-5
- UNII-ZF80H5GXUF
- NSC 34809
- RCRA waste no. U011
- EPA Pesticide Chemical Code 004401
- 3-Amino-1,2,4-triazol
- 3-Amino-1.2.4-Triazole
- 2H-1,2,4-triazol-3-amine
- MSS aminotriazole
- 4lpf
- 3-Amino-[1,2,4]TRIAZOLE
- Aminotriazole bayer
- 1H-1,2,4-Triazole, 3-amino-
- 5-amino-s-triazole
- EINECS 265-695-7
- 4H-[1,2,4]Triazol-3-Yl-Amine
- MFCD00053362
- MFCD00982302
- Domatol (Salt/Mix)
- Tomatol (Salt/Mix)
- delta2-1,2,4-Triazoline, 5-imino-
- 1794936-83-6
- 3-amino-1
- 5-amino-1
- AMITROLE [HSDB]
- AMITROLE [IARC]
- 5-amino-1H-1
- AMITROLE [MI]
- Azaplant Kombi (Salt/Mix)
- 1,2,4-triazol-3-ylamine
- US9138393, Amitrol
- US9144538, Amitrol
- 3-amino -1,2,4-triazole
- MLS001066382
- BIDD:ER0572
- BIDD:GT0663
- SPECTRUM1505154
- 3-amino-4h-1,2,4-triazole
- 1H-[1,2,4]triazole-5-amine
- 3-amino-4H-[1,2,4]triazole
- BDBM181126
- HMS2796E16
- 1H-[1,2,4]triazol-3-yl-amine
- BCP22056
- NSC-7243
- NSC34809
- STR00855
- 3-Amino-1,2,4-triazole, 95%
- Tox21_201782
- Tox21_302991
- BBL012592
- BDBM50204936
- ENT-25445
- STK300039
- AKOS001041416
- AKOS003234051
- AKOS022504310
- CCG-214705
- HY-W027592
- PS-9367
- SB37916
- NCGC00096037-01
- NCGC00096037-02
- NCGC00256352-01
- NCGC00259331-01
- SMR000434277
- TRAPIDIL IMPURITY B [EP IMPURITY]
- 4H-1,2,4-Triazol-3-amine, AldrichCPR
- Amitrole (3-Amino-1H-1,2,4-triazole)
- Amitrol, PESTANAL(R), analytical standard
- DB-024447
- DB-090667
- A0432
- CS-0071616
- CS-0166917
- NS00014227
- S5977
- 2,3,5,6-Tetraazabicyclo[2.1.1]hex-1-ene
- 3-Amino-1,2,4-triazole, >=95% (TLC)
- EN300-17045
- A-7200
- D70019
- E85243
- AE-641/30106057
- AO-090/25045001
- Q423314
- W-203416
- Z56866006
- F0001-1598
- F1716-0525
- 138903B1-BF0B-45AC-842E-8F06589B06F2
- Trapidil impurity B, European Pharmacopoeia (EP) Reference Standard
- 65312-62-1
213.0 1
99.0 0.40
171.0 0.32
214.0 0.21
228.0 0.21
285.0 1
171.0 0.38
130.0 0.29
99.0 0.29
100.0 0.28
85.0508 100
57.0449 3.22
58.0401 1.10
85.0508 999
58.0391 467
57.0441 389
43.0293 999
42.0211 111
58.0396 75
85.0504 49
31.0292 34
85 100
84 21.84
43 15.47
57 9.02
42 4.42
H361 (97.6%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H373 (98.8%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
H411 (99.4%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P203, P260, P273, P280, P318, P319, P391, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 170 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Repr. 2 (97.6%)
STOT RE 2 (98.8%)
Aquatic Chronic 2 (99.4%)
Reproductive toxicity - category 2
Specific target organ toxicity (repeated exposure) - category 2
Hazardous to the aquatic environment (chronic) - category 2
Excerpt from NIOSH Pocket Guide for Amitrole:
Exposure Routes: Inhalation, ingestion, skin and/or eye contact
Symptoms: Irritation eyes, skin; dyspnea (breathing difficulty), muscle spasms, ataxia, anorexia, salivation, increased body temperature; lassitude (weakness, exhaustion), skin dryness, depression (thyroid function suppression)
Target Organs: Eyes, skin, thyroid
Cancer Site: [in animals: liver, thyroid & pituitary gland tumors] (NIOSH, 2024)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)
(See general first aid procedures)
Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
Skin: Water wash immediately - If this chemical contacts the skin, immediately wash the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and wash the skin with water. If symptoms occur after washing, get medical attention immediately.
Breathing: Respiratory support
Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.
FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
STORAGE PRECAUTIONS: You should keep this material in a tightly closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)
Ca [N.D.]
See: IDLH INDEX
Excerpt from NIOSH Pocket Guide for Amitrole:
Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.
Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.
Wash skin: DAILY - The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.
Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.
Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.
Provide:
• EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection.
• QUICK DRENCH - Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2024)
(See personal protection and sanitation codes)
Skin: Prevent skin contact - Wear appropriate personal protective clothing to prevent skin contact.
Eyes: Prevent eye contact - Wear appropriate eye protection to prevent eye contact.
Wash skin: Daily - The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.
Remove: When wet or contaminated
Change: Daily - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.
Provide: Eyewash, Quick drench
NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters.
Any appropriate escape-type, self-contained breathing apparatus
Hazard Traits - Carcinogenicity
Authoritative List - NTP RoC - reasonable; Prop 65
Report - regardless of intended function of ingredient in the product
Volume 79: (2001) Some Thyrotropic Agents
Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)
Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects. See Guidelines for Reproductive Toxicity Risk Assessment.
Skin Sensitizer - An agent that can induce an allergic reaction in the skin.
NTP Carcinogen - Reasonably anticipated to be a human carcinogen.
ACGIH Carcinogen - Confirmed Animal.
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=KLSJWNVTNUYHDU-UHFFFAOYSA-N
- Australian Industrial Chemicals Introduction Scheme (AICIS)1H-1,2,4-Triazol-3-aminehttps://services.industrialchemicals.gov.au/search-inventory/
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- ILO-WHO International Chemical Safety Cards (ICSCs)
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/4H-1,2,4-Triazol-3-aminehttps://commonchemistry.cas.org/detail?cas_rn=65312-61-01H-1,2,4-Triazol-5-aminehttps://commonchemistry.cas.org/detail?cas_rn=61-82-51,2-Dihydro-3H-1,2,4-triazol-3-iminehttps://commonchemistry.cas.org/detail?cas_rn=65312-62-1
- ChemIDplusAmitrole [ANSI:BSI:ISO]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0000061825(4H)-1,2,4-Triazol-3-aminehttps://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0065312610ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
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- EPA Chemical and Products Database (CPDat)EPA CPDat Classificationhttps://www.epa.gov/chemical-research/chemical-and-products-database-cpdat
- EPA Pesticide Ecotoxicity Database
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- Hazardous Chemical Information System (HCIS), Safe Work Australia
- NITE-CMC3-Amino-1H-1,2,4-triazole, (alias Amitrole) - FY2009 (Revised classification)https://www.chem-info.nite.go.jp/chem/english/ghs/09-mhlw-2063e.htmlAmitrol - FY2006 (New/original classication)https://www.chem-info.nite.go.jp/chem/english/ghs/06-imcg-0085e.html
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- IUPAC Digitized pKa Dataset1,2,4-Triazole, 3-amino-https://github.com/IUPAC/Dissociation-Constants
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- NIST Mass Spectrometry Data CenterLICENSEData covered by the Standard Reference Data Act of 1968 as amended.https://www.nist.gov/srd/public-law3-Amino-s-triazolehttp://www.nist.gov/srd/nist1a.cfm
- SpectraBase3-AMINO-1H-1,2,4-TRIAZOLEhttps://spectrabase.com/spectrum/6Vv4x9lnClb1,2,4-Triazol-3-aminehttps://spectrabase.com/spectrum/FMOiezp18Gk3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/2XPL7DiNs7r3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/I4DFPLdlNoP3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/BDoInC9iZwN3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/27oQ1az6BGn3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/DGpqSHvRDtw3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/LGgdhfdsMqv3-AMINO-1,2,4-TRIAZOLEhttps://spectrabase.com/spectrum/7XpkztXP3E03-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/5zIOALljZjlAMITROLE /AMITROLEhttps://spectrabase.com/spectrum/CQ5iHJ5kibS3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/8HU3mUF5mNw3-Amino-1,2,4-triazolehttps://spectrabase.com/spectrum/5s1JcwU5Z3f
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