An official website of the United States government

Mercuric nitrate

PubChem CID
24864
Structure
Mercuric nitrate_small.png
Molecular Formula
Synonyms
  • MERCURIC NITRATE
  • Mercury nitrate
  • Mercury dinitrate
  • 10045-94-0
  • Mercury pernitrate
Molecular Weight
324.60 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Dates
  • Create:
    2005-08-08
  • Modify:
    2025-01-18
Description
Mercuric nitrate appears as a white crystalline solid. Toxic by inhalation, ingestion and/or skin contact. Prolonged exposure to fire or heat may result in an explosion. Produces toxic oxides of nitrogen when heated to decomposition. Used to make other chemicals and in medicine.

1 Structures

1.1 2D Structure

Chemical Structure Depiction
Mercuric nitrate.png

1.2 3D Status

Conformer generation is disallowed since MMFF94s unsupported element, mixture or salt

2 Names and Identifiers

2.1 Computed Descriptors

2.1.1 IUPAC Name

mercury(2+);dinitrate
Computed by Lexichem TK 2.7.0 (PubChem release 2021.10.14)

2.1.2 InChI

InChI=1S/Hg.2NO3/c;2*2-1(3)4/q+2;2*-1
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

2.1.3 InChIKey

ORMNPSYMZOGSSV-UHFFFAOYSA-N
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

2.1.4 SMILES

[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Hg+2]
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)

2.2 Molecular Formula

HgN2O6

Hg(NO3)2

HgN2O6
Computed by PubChem 2.2 (PubChem release 2021.10.14)

2.3 Other Identifiers

2.3.1 CAS

10045-94-0
13465-31-1

2.3.3 Deprecated CAS

8046-70-6, 820986-03-6
820986-03-6

2.3.4 European Community (EC) Number

2.3.5 UNII

2.3.6 UN Number

2.3.7 DSSTox Substance ID

2.3.8 ICSC Number

2.3.9 Wikidata

2.3.10 Wikipedia

2.4 Synonyms

2.4.1 MeSH Entry Terms

  • mercury nitrate
  • mercury nitrate (1:1)
  • mercury nitrate (2:1)
  • mercury nitrate (2:1), HNO3-203Hg-labeled

2.4.2 Depositor-Supplied Synonyms

3 Chemical and Physical Properties

3.1 Computed Properties

Property Name
Molecular Weight
Property Value
324.60 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Donor Count
Property Value
0
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Acceptor Count
Property Value
6
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Rotatable Bond Count
Property Value
0
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Exact Mass
Property Value
325.946279 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Monoisotopic Mass
Property Value
325.946279 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Topological Polar Surface Area
Property Value
126 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Heavy Atom Count
Property Value
9
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
18.8
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
3
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)

3.2 Experimental Properties

3.2.1 Physical Description

Mercuric nitrate appears as a white crystalline solid. Toxic by inhalation, ingestion and/or skin contact. Prolonged exposure to fire or heat may result in an explosion. Produces toxic oxides of nitrogen when heated to decomposition. Used to make other chemicals and in medicine.
White to yellow powder or crystals with a sharp odor; [HSDB]
COLOURLESS CRYSTALS OR WHITE HYGROSCOPIC POWDER.

3.2.2 Color / Form

White or slightly yellow crystal powder
Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1004
Deliquescent crystalline
Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1004
White granules or crystalline powder; colorless, rhombic crystals.
Prager, J.C. Environmental Contaminant Reference Databook Volume 2. New York, NY: Van Nostrand Reinhold, 1996., p. 563

3.2.3 Odor

Sharp odor
Weiss, G.; Hazardous Chemicals Handbook. 1986, Noyes Data Corporation, Park Ridge, NJ 1986., p. 655

3.2.4 Melting Point

79 °C
Lide, D.R. (ed.). CRC Handbook of Chemistry and Physics. 79th ed. Boca Raton, FL: CRC Press Inc., 1998-1999., p. 4-71

3.2.5 Solubility

VERY SOL IN COLD WATER; SOL IN ACETONE, NITRIC ACID, AMMONIA; INSOL IN ALCOHOL /MERCURIC NITRATE HEMIHYDRATE/
Weast, R.C. (ed.). Handbook of Chemistry and Physics. 66th ed. Boca Raton, Florida: CRC Press Inc., 1985-1986., p. B-107
Weast, R.C. (ed.). Handbook of Chemistry and Physics. 66th ed. Boca Raton, Florida: CRC Press Inc., 1985-1986., p. B-107
Soluble in small amount of water and in dilute acids.
Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1004
Soluble in water; insoluble in ethanol
Lide, D.R. (ed.). CRC Handbook of Chemistry and Physics. 79th ed. Boca Raton, FL: CRC Press Inc., 1998-1999., p. 4-71
Solubility in water: good

3.2.6 Density

4.3 at 68 °F (USCG, 1999) - Denser than water; will sink
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
4.3 at 20 °C (solid)
Weiss, G.; Hazardous Chemicals Handbook. 1986, Noyes Data Corporation, Park Ridge, NJ 1986., p. 655
4.4 g/cm³

3.2.7 Stability / Shelf Life

Decomposed by heat
The Merck Index. 10th ed. Rahway, New Jersey: Merck Co., Inc., 1983., p. 654

3.2.8 Corrosivity

Solution will corrode most metals.
Weiss, G.; Hazardous Chemicals Handbook. 1986, Noyes Data Corporation, Park Ridge, NJ 1986., p. 654

3.2.9 Other Experimental Properties

Mercuric nitrate dissolves in water, then forms a cloudy acid solution. The reaction is not hazardous.
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.
Solid in contact with wood or paper may cause fire.
Weiss, G.; Hazardous Chemicals Handbook. 1986, Noyes Data Corporation, Park Ridge, NJ 1986., p. 655
Decomposed by hot water
Ashford, R.D. Ashford's Dictionary of Industrial Chemicals. London, England: Wavelength Publications Ltd., 1994., p. 560
Thermal decomposition leads to red mercury(II) oxide.
Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA16 (90) 289
With much water or on boiling with water an insol basic salt is formed; deliquescent odor of nitric acid; white or slightly yellow crystalline powder; density: 4.3; sol in small amt water; sol in dilute acids /Mercuric nitrate hydrate/
Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1004

3.3 Chemical Classes

Metals -> Mercury Compounds, Inorganic

4 Spectral Information

4.1 IR Spectra

4.1.1 FTIR Spectra

Technique
KBr WAFER
Source of Sample
Mallinckrodt Inc., St. Louis, Missouri
Copyright
Copyright © 1980, 1981-2024 John Wiley & Sons, Inc. All Rights Reserved.
Thumbnail
Thumbnail

4.2 Raman Spectra

1 of 2
Instrument Name
Bio-Rad FTS 175C with Raman accessory
Technique
FT-Raman
Source of Sample
Fluka Chemie AG, Buchs, Switzerland
Catalog Number
83369
Copyright
Copyright © 1980, 1981-2024 John Wiley & Sons, Inc. All Rights Reserved.
Thumbnail
Thumbnail
2 of 2
Instrument Name
Bio-Rad FTS 175C with Raman accessory
Technique
FT-Raman
Source of Sample
Fluka Chemie AG, Buchs, Switzerland
Catalog Number
83369
Copyright
Copyright © 1980, 1981-2024 John Wiley & Sons, Inc. All Rights Reserved.
Thumbnail
Thumbnail

6 Chemical Vendors

7 Drug and Medication Information

7.1 Drug Warnings

... /Some/ ointments contain ... mercuric nitrate (Hg(HNO3)2.2H2O). ... Dogs & cats are particularly susceptible to toxic effects of mercury from mercurial ointments, due to both direct absorption & to licking of parts to which the ointment has been applied. Poisoning in cattle has also been recorded after use of ointments containing ... mercuric nitrate. ... The sensitivity ... /of sheep & cattle/ is so great that fatal cases of poisoning have occurred as result of treatment, with ointments containing mercury, of other animals kept in the same house.
Clarke, M. L., D. G. Harvey and D. J. Humphreys. Veterinary Toxicology. 2nd ed. London: Bailliere Tindall, 1981., p. 61

8 Pharmacology and Biochemistry

8.1 Absorption, Distribution and Excretion

FETAL UPTAKE OF METHYL MERCURY WAS GREATER THAN OF MERCURIC NITRATE AT 15 & 20 DAYS OF GESTATION. DECIDUAL TISSUE UPTAKE WAS LOW & CONSTANT FOR BOTH, YOLK SAC TOOK UP HIGHER % MERCURIC NITRATE THAN METHYL MERCURY.
MANSOUR MM ET AL; AM J OBSTET GYNECOL 119 (4): 557-62 (1974)
(2O3)HG-MERCURIC NITRATE WAS ADMIN TO PREGNANT HAMSTERS EARLY ON 8TH GESTATON DAY. SIGNIFICANT CONCN OF HG MEASURED 24 & 96 HR AFTER INJECTION WAS FOUND IN MATERNAL, PLACENTAL, & EMBRYONIC TISSUES.
GALE TF, HANLON DP; ENVIRON RES 12 (1): 26-31 (1976)

8.2 Biological Half-Life

BIOLOGICAL HALF-LIVES & ELIMINATION FROM BACTERIAL CELLS, MOSQUITO LARVAE, & GUPPIES ARE DISCUSSED FOR MERCURY COMPOUNDS INCL MERCURIC NITRATE WITH RESPECT TO TEMP, TIME, AND BUFFER & WATER CELL WASHES. HALF-LIFE DECR WHEN TEMP INCR.
HAMDY MK, PRABHU NV; BULL ENVIRON CONTAM TOXICOL 19 (3): 365-73 (1978)
IN FEMALE FISH (POECILIA RETICULATA) ACCUMULATION RATES OF MERCURY FROM MERCURIC NITRATE OR METHYL MERCURY CHLORIDE IN DEIONIZED WATER AT 0.1-20 NG HG/ML INCR WITH INCR HG CONCN & DECR IN PRESENCE OF COMPLEXING AGENTS. RELEASE OF MERCURIC NITRATE FROM FISH OCCURRED IN 2 STEPS WITH HALF-LIFE OF 4.2 & 67.7 DAYS. THE MERCURY RELEASED FROM MERCURIC NITRATE EXPOSED FISH IN THE 2ND STEP INCREASED WITH INCREASING EXPOSURE TIME & REPRESENTS MERCURY CONVERTED TO METHYL MERCURY IN THE FISH.
KRAEMER HJ, NEIDHART B; PROC INT CONF NUCL METHODS ENVIRON RES 2ND; ISS CONF-740701: 213-23 (1974)

9 Use and Manufacturing

9.1 Uses

Sources/Uses
Used as an analytical reagent, in bronzing, as a nitrating agent, and in organic synthesis; Was used in the past to manufacture felt hats; [HSDB]
Mfr of felt; mercury fulminate; destroying Phylloxera
Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1004
IN BRONZING; IN THE INSIDE OF FIELD GLASSES
Browning, E. Toxicity of Industrial Metals. 2nd ed. New York: Appleton-Century-Crofts, 1969., p. 227
ANALYTICAL REAGENT; PREPN OF MERCURIC NITRATE STD SOLN
Association of Official Analytical Chemists. Official Methods of Analysis. 10th ed. and supplements. Washington, DC: Association of Official Analytical Chemists, 1965. New editions through 13th ed. plus supplements, 1982., p. 12/276 16.170
Nitration of aromatic organic compounds
Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 712
For more Uses (Complete) data for MERCURIC NITRATE (7 total), please visit the HSDB record page.

9.1.1 Use Classification

Hazard Classes and Categories ->

9.2 Methods of Manufacturing

By action of hot nitric acid on mercury.
Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 712

9.3 Formulations / Preparations

97.0% min assay /available/
Fluka; Catalog 14, Chemicals and Biochemicals p. 622 (1984)

9.4 General Manufacturing Information

EPA TSCA Commercial Activity Status
Nitric acid, mercury(2+) salt (2:1): ACTIVE
EPA TSCA Regulatory Flag
12C - indicates a substance that is prohibited to be exported from the Unites States under TSCA section 12(c).

10 Safety and Hazards

10.1 Hazards Identification

10.1.1 GHS Classification

1 of 2
View All
Pictogram(s)
Oxidizer
Acute Toxic
Health Hazard
Environmental Hazard
Signal
Danger
GHS Hazard Statements

H272 (49.4%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H300+H310+H330 (49.4%): Fatal if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

H300 (98.7%): Fatal if swallowed [Danger Acute toxicity, oral]

H310 (98.7%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H330 (98.7%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H400 (98.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (98.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statement Codes

P210, P220, P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P370+P378, P391, P403+P233, P405, and P501

(The corresponding statement to each P-code can be found at the GHS Classification page.)

ECHA C&L Notifications Summary

Aggregated GHS information provided per 77 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

10.1.2 Hazard Classes and Categories

Ox. Sol. 2 (49.4%)

Acute Tox. 2 (98.7%)

Acute Tox. 1 (98.7%)

Acute Tox. 2 (98.7%)

STOT RE 2 (100%)

Aquatic Acute 1 (98.7%)

Aquatic Chronic 1 (98.7%)

Acute toxicity (Oral) - Category 2

Acute toxicity (Dermal) - Category 2

Skin corrosion/irritation - Category 1A-1C

Serious eye damage/eye irritation - Category 1

Skin sensitization - Category 1

Germ cell mutagenicity - Category 2

Reproductive toxicity - Category 2

Specific target organ toxicity - Single exposure - Category 1 (kidney), Category 2 (respiratory system)

Specific target organ toxicity - Repeated exposure - Category 1 (central nervous system, kidney)

Hazardous to the aquatic environment (Acute) - Category 1

Hazardous to the aquatic environment (Long-term) - Category 1

10.1.3 Health Hazards

Acute systemic poisoning may be fatal within a few minutes; death by uremic poisoning is usually delayed 5-12 days. Acute poisoning has resulted from inhaling dust concentrations of 1.2-8.5 mg/m 3 of air; symptoms inc lude tightness and pain in chest, coughing, and difficulty in breathing. Ingestion causes necrosis, pain, vomiting, and severe purging. Contact with eyes causes ulceration of conjunctiva and cornea. Contact with skin causes irritation and po ssible dermatitis; systemic poisoning can occur by absorption through skin. (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
ERG 2024, Guide 141 (Mercuric nitrate)

· Toxic by ingestion.

· Inhalation of dust is toxic.

· Fire may produce irritating, corrosive and/or toxic gases.

· Contact with substance may cause severe burns to skin and eyes.

· Runoff from fire control or dilution water may cause environmental contamination.

10.1.4 Fire Hazards

Special Hazards of Combustion Products: Vapors from fire may contain toxic mercury and oxides of nitrogen.

Behavior in Fire: May increase intensity of fire if in contact with burning material (USCG, 1999)

U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
ERG 2024, Guide 141 (Mercuric nitrate)

· These substances will accelerate burning when involved in a fire.

· May explode from heat or contamination.

· Some may burn rapidly.

· Some will react explosively with hydrocarbons (fuels).

· May ignite combustibles (wood, paper, oil, clothing, etc.).

· Containers may explode when heated.

· Runoff may create fire or explosion hazard.

Not combustible but enhances combustion of other substances. Gives off irritating or toxic fumes (or gases) in a fire.

10.1.5 Hazards Summary

See Mercury; Very toxic by ingestion; Cases of poisoning reported after inhalation exposures of 1.2-8.5 mg/m 3; [CAMEO] See Mercury, inorganic compounds and the linked diseases.

10.1.6 Fire Potential

Dangerous fire risk in contact with organic materials.
International Labour Office. Encyclopedia of Occupational Health and Safety. Vols. I&II. Geneva, Switzerland: International Labour Office, 1983., p. 654
Non-combustible, but will accelerate the burning of combustible materials.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
May increase the intensity of fire if in contact with burning material. Solid in contact with wood or paper may cause fire. /Mercuric nitrate monohydrate/
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.

10.1.7 EPA Hazardous Waste Number

D009; Mercury. A waste containing mercury may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. /Mercury/

10.2 Safety and Hazard Properties

10.2.1 OSHA Standards

Vacated 1989 OSHA PEL still enforced in some states: Hg vapor, TWA 0.05 mg/cu m, skin; Non-alkyl cmpds, Ceiling 0.1 mg/cu m, skin. /Mercury cmpd, as Hg, (except (organo) alkyls)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 367

10.2.2 NIOSH Recommendations

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.05 mg/cu m, skin (Hg vapor). /Mercury [except (organo) alkyls] (as Hg)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 192
Recommended Exposure Limit: Ceiling Value: 0.1 mg/cu m, skin. /Mercury compounds [except (organo) alkyls] (as Hg)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 192

10.3 First Aid Measures

Inhalation First Aid
Fresh air, rest. Refer for medical attention.
Skin First Aid
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention .
Eye First Aid
Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion First Aid
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

10.3.1 First Aid

INHALATION: remove to fresh air; get medical attention.

INGESTION: alimentary absorption is very rapid; action during first 10-15 min. determines prognosis. Give egg whites, milk, or activated charcoal and induce vomiting; consult physician.

EYES or SKIN: flush with water. (USCG, 1999)

U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
ERG 2024, Guide 141 (Mercuric nitrate)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingestedor inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuouscompressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Contaminated clothing may be a fire risk when dry.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

10.4 Fire Fighting

Excerpt from ERG Guide 141 [Oxidizers - Toxic]:

SMALL FIRE: Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

LARGE FIRE: Flood fire area with water from a distance. Do not move cargo or vehicle if cargo has been exposed to heat. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

In case of fire in the surroundings, use appropriate extinguishing media.

10.4.1 Fire Fighting Procedures

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672

10.5 Accidental Release Measures

Public Safety: ERG 2024, Guide 141 (Mercuric nitrate)

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

Spill or Leak: ERG 2024, Guide 141 (Mercuric nitrate)

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

Small Dry Spill

· With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

Large Spill

· Dike far ahead of spill for later disposal.

10.5.1 Isolation and Evacuation

Excerpt from ERG Guide 141 [Oxidizers - Toxic]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Evacuation: ERG 2024, Guide 141 (Mercuric nitrate)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

Large Spill

· Consider initial downwind evacuation for at least 100 meters (330 feet).

Fire

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

10.5.2 Spillage Disposal

Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.

10.5.3 Cleanup Methods

Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
Water spill: Add dilute caustic soda (NaOH). IF dissolved, apply sodium sulfide (Na2S) solutuion to precipate heavy metals. If dissolved in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amt. Use mechanical dredges or lifts to remove immobolized masses of pollutants and precipitates. Allow to aerate.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
Mercury spills should be cleaned up immediately by use of a special vacuum cleaner. Then the area should be washed with a dilute calcium sulfide solution. Small quantities of mercury can be picked up by mixing with copper metal granules. ... /Mercury/
Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. 15(81) 167
Mercury removal from waste water can be accomplished by these processes: BMS process; Chlorine is added to the waste water, oxidizing any mercury present to the ionic state. The BMS adsorbent (an activated carbon concentrate of sulfur cmpd on its surface) is used to collect ionic mercury. The spent adsorbent is then distilled to recover the mercury, leaving a carbon residue for reuse or disposal. TMR IMAC Process; Waste water is fed into a reactor, whereby a slight excess of chlorine is maintained, oxidizing any mercury present to ionic mercury. The liquid is then passed through the TMR IMAC ion-exchange resin where mercury ions are adsorbed. The mercury is then stripped from the spent resin with hydrochloric acid solution. /Mercury cmpds/
Environment Canada; Tech Info for Problem Spills: Mercury (Draft) p.59 (1982)
For more Cleanup Methods (Complete) data for MERCURIC NITRATE (6 total), please visit the HSDB record page.

10.5.4 Disposal Methods

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D009, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.
40 CFR 240-280, 300-306, 702-799 (7/1/96)

10.5.5 Preventive Measures

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers.
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
Personnel protection: ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amount of water or soap and water.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672
Preventative measure: adequate ventilation; careful attention to good housekeeping, e.g., avoidance of spills, and prompt and proper cleaning if a spill occurs; all containers of mercury and its compounds should be kept tightly closed; should be washed on a regular basis with dilute calcium sulfide solution or other suitable reactant; floors should be nonporous; all workers directly involved in the plant operation should shower thoroughly each day before leaving. /Mercury compounds/
Prager, J.C. Environmental Contaminant Reference Databook Volume 2. New York, NY: Van Nostrand Reinhold, 1996., p. 559

10.6 Handling and Storage

10.6.1 Nonfire Spill Response

Excerpt from ERG Guide 141 [Oxidizers - Toxic]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk.

SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

LARGE SPILL: Dike far ahead of spill for later disposal. (ERG, 2024)

10.6.2 Safe Storage

Separated from combustible substances, reducing agents and food and feedstuffs. See Chemical Dangers. Keep in the dark. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Well closed. Store only in original container.

10.6.3 Storage Conditions

Storage temperature: Ambient; Venting: Open
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.

10.7 Exposure Control and Personal Protection

Protective Clothing: ERG 2024, Guide 141 (Mercuric nitrate)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

Maximum Allowable Concentration (MAK)
0.02 [mg/m3], as Hg, inhalable fraction[German Research Foundation (DFG)]

10.7.1 Permissible Exposure Limit (PEL)

0.1 [mg/m3], as Hg

10.7.2 Immediately Dangerous to Life or Health (IDLH)

10 mg Hg/m3 (NIOSH, 2024)
10.0 [mg/m3], as Hg
10 mg/cu m (as Hg) /Mercury cmpd (except (organo) alkyl compounds (as Hg)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 192

10.7.3 Threshold Limit Values (TLV)

0.02 [mg/m3], as Hg
8 hr Time Weighted Avg (TWA): 0.025 mg/cu m, skin /Mercury, elemental and inorganic forms, as Hg/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 37
Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Mercury, elemental and inorganic forms, as Hg/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 5
A4: Not classifiable as a human carcinogen./Mercury, elemental and inorganic forms, as Hg/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 37
Biological Exposure Index (BEI): Determinant: total inorganic mercury in urine; Sampling Time: prior to shift; BEI: 35 ug/g creatine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 105
Biological Exposure Index (BEI): Determinant: total inorganic mercury in blood; Sampling Time: end of shift at end of workweek; BEI: 15 ug/L. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 105
(as Hg): 0.025 mg/m

10.7.4 Occupational Exposure Limits (OEL)

EU-OEL
(as Hg): 0,02 mg/m
MAK (Maximale Arbeitsplatz Konzentration)
(as Hg, inhalable fraction): 0.02 mg/m

10.7.5 Emergency Response Planning Guidelines

Emergency Response: ERG 2024, Guide 141 (Mercuric nitrate)

Small Fire

· Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

Large Fire

· Flood fire area with water from a distance.

· Do not move cargo or vehicle if cargo has been exposed to heat.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

10.7.6 Other Standards Regulations and Guidelines

On the basis of toxicity expts on lab animals with exposure to mercuric nitrate, a value of 0.05 mg/cu m was obtained as the max permissible Hg concn in the workplace air. For very short and occasional exposures, the 0.2 mg/cu m value is acceptable.
Trakhtenberg IM et al; Gig T Prof Zabol 12: 37-41 (1984)

10.7.7 Inhalation Risk

A harmful concentration of airborne particles can be reached quickly when dispersed.

10.7.8 Effects of Short Term Exposure

The substance is severely irritating to the eyes, skin and respiratory tract. The substance may cause effects on the gastrointestinal tract and kidneys. This may result in tissue lesions and kidney failure. Medical observation is indicated.

10.7.9 Effects of Long Term Exposure

Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the central nervous system, kidneys and peripheral nervous system. This may result in ataxia, sensory and memory disturbances, tremors, muscle weakness and kidney impairment. The substance may have effects on male fertility. May cause heritable genetic damage to human germ cells.

10.7.10 Personal Protective Equipment (PPE)

Dust mask; goggles or face shield; protective gloves (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
Personnel protection: ... Wear appropriate chemical protective gloves, boots, and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 672

10.7.11 Preventions

Exposure Prevention
AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
Inhalation Prevention
Use local exhaust or breathing protection.
Skin Prevention
Protective gloves. Protective clothing.
Eye Prevention
Wear face shield or eye protection in combination with breathing protection.
Ingestion Prevention
Do not eat, drink, or smoke during work. Wash hands before eating.

10.8 Stability and Reactivity

10.8.1 Air and Water Reactions

Deliquescent. Soluble in a small amount of water. With much water or on boiling with water, an insoluble basic salt is formed.

10.8.2 Reactive Group

Nitrate and Nitrite Compounds, Inorganic

10.8.3 Reactivity Alerts

Strong Oxidizing Agent

10.8.4 Reactivity Profile

MERCURIC NITRATE is noncombustible, but, as an oxidizing agent, will accelerate the burning of combustible materials. If large quantities are involved in a fire or the combustible material is finely divided, an explosion may result. Light sensitive. Mixtures with alkyl esters may explode, owing to the formation of alkyl nitrates. Mixtures with phosphorus, tin(II) chloride, or other reducing agents may react explosively [Bretherick 1979. p. 108-109]. Acetylene forms a sensitive acetylide when passed into an aqueous solution of mercuric nitrate [Mellor 4:933. 1946-47]. Should not be mixed with alcohols as explosive mercury fulminates may be formed [Bahme 1961. p. 9]. Is violently reduced by hypophosphoric acid [Mellor 4:993. 1946-47]. Reacts with phosphine to give a yellow precipitate that explodes when heated or subjected to shock [Mellor 4:993. 1946-47].

10.8.5 Hazardous Reactivities and Incompatibilities

ACETYLENE FORMS A SENSITIVE ACETYLIDE WHEN PASSED INTO AQ SOLN OF MERCURIC NITRATE. MERCURIC NITRATE IS VIOLENTLY REDUCED TO MERCURY BY HYPOPHOSPHORIC ACID. MERCURIC NITRATE REACTS WITH UNSATURATED & AROMATIC CMPD WITH VIOLENCE IF GIVEN TIME TO GENERATE ENOUGH HEAT.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 491-117
Gas oil was stirred vigorously with the finely divided solid nitrate to complete the removal of sulfur compounds. After the mixture had congealed, preventing further stirring, a violent reaction set in, which reached incandescence, accompanied by vigorous evolution of nitrous fumes. This was attributed to the self-catalyzed nitrating action of mercury nitrate in a semi-solid environment unable to lose heat effectively. A similar occurrence was observed when crushed nitrate was just covered with cracked naphtha. ... This type of hazard was known in cracked distillates containing high proportions of unsaturated and aromatic cmpd, when allowed to stand in prolonged contact with mercury(2+) nitrate. The hazard may be avoided by using several small portions of the salt sequentially and working with 100 g portions of hydrocarbons.
Bretherick, L. Handbook of Reactive Chemical Hazards. 4th ed. Boston, MA: Butterworth-Heinemann Ltd., 1990, p. 1272
ALCOHOL SHOULD NOT BE MIXED WITH MERCURIC NITRATE, AS EXPLOSIVE FULMINATE MAY BE FORMED. THE REACTION OF PHOSPHINES & MERCURIC NITRATE GIVES A YELLOW PRECIPITATE WHICH EXPLODES WHEN HEATED OR SUBJECTED TO SHOCK. AN EXPLOSION OCCURRED DURING THE USE OF MERCURIC NITRATE FOR DETERMINING SULFUR IN BALL'S REACTION.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 491-117
Phosphine reacts with aqueous salt solution to give a complex nitrate phosphide, which when dry explodes on heating or impact.
Bretherick, L. Handbook of Reactive Chemical Hazards. 4th ed. Boston, MA: Butterworth-Heinemann Ltd., 1990, p. 1273
Phosphinic ('hypophosphorus') acid violently reduces the salt to the metal.
Bretherick, L. Handbook of Reactive Chemical Hazards. 4th ed. Boston, MA: Butterworth-Heinemann Ltd., 1990, p. 1273

10.9 Transport Information

10.9.1 DOT Emergency Guidelines

/GUIDE 141: OXIDIZERS - TOXIC/ Fire or Explosion: These substances will accelerate burning when involved in a fire. May explode from heat or contamination. Some may burn rapidly. Some will react explosively with hydrocarbons (fuels). May ignite combustibles (wood, paper, oil, clothing, etc.). Containers may explode when heated. Runoff may create fire or explosion hazard.
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 141: OXIDIZERS - TOXIC/ Health: Toxic by ingestion. Inhalation of dust is toxic. Fire may produce irritating, corrosive and/or toxic gases. Contact with substance may cause severe burns to skin and eyes. Runoff from fire control or dilution water may cause pollution.
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 141: OXIDIZERS - TOXIC/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 141: OXIDIZERS - TOXIC/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection.
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
For more DOT Emergency Guidelines (Complete) data for MERCURIC NITRATE (8 total), please visit the HSDB record page.

10.9.2 Shipping Name / Number DOT/UN/NA/IMO

UN 1625; MERCURIC NITRATE
IMO 6.1; MERCURIC NITRATE

10.9.3 Standard Transportation Number

49 187 69; Mercuric nitrate, oxidizer

10.9.4 Shipment Methods and Regulations

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
49 CFR 171.2; U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of February 15, 2006: https://www.ecfr.gov
The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.
International Air Transport Association. Dangerous Goods Regulations. 47th Edition. Montreal, Quebec Canada. 2006., p. 214
The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
International Maritime Organization. International Maritime Dangerous Goods Code. London, UK. 2004., p. 77

10.9.5 DOT Label

Poison

10.9.6 Packaging and Labelling

Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Severe marine pollutant.

10.9.7 EC Classification

Symbol: T+, N; R: 26/27/28-33-50/53; S: (1/2)-13-28-45-60-61; Note: A, 1

10.9.8 UN Classification

UN Hazard Class: 6.1; UN Pack Group: II

10.10 Regulatory Information

The Australian Inventory of Industrial Chemicals
Chemical: Nitric acid, mercury(2+) salt, hemihydrate
The Australian Inventory of Industrial Chemicals
Chemical: Nitric acid, mercury(2+) salt
New Zealand EPA Inventory of Chemical Status
Mercury (II) nitrate: HSNO Approval: HSR007131 Approved with controls
New Zealand EPA Inventory of Chemical Status
Mercury (II) nitrate: HSNO Approval: HSR006211 Approved with controls

10.10.1 Atmospheric Standards

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Mercuric nitrate is included on this list.
Clean Air Act as amended in 1990, Sect. 112 (b) (1) Public Law 101-549 Nov. 15, 1990

10.10.2 Federal Drinking Water Standards

EPA 2 ug/l /Mercury/
USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present

10.10.3 Federal Drinking Water Guidelines

EPA 2 ug/l /Mercury/
USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present

10.10.4 State Drinking Water Guidelines

(AZ) ARIZONA 3 ug/l /Mercury/
USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present

10.10.5 Clean Water Act Requirements

Mercuric nitrate is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.
40 CFR 116.4 (7/1/99)

10.10.6 CERCLA Reportable Quantities

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 10 lb or 4.54 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).
40 CFR 302.4 (7/1/99)

10.10.7 RCRA Requirements

D009; A solid waste containing mercury may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Mercury/
40 CFR 261.24 (7/1/99

10.11 Other Safety Information

Chemical Assessment

IMAP assessments - Nitric acid, mercury(2+) salt: Environment tier I assessment

IMAP assessments - Nitric acid, mercury(2+) salt: Human health tier I assessment

10.11.1 Toxic Combustion Products

Vapors from fire may contain toxic mercury & oxides of nitrogen. /Mercuric nitrate monohydrate/
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.

11 Toxicity

11.1 Toxicological Information

11.1.1 Evidence for Carcinogenicity

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 37

11.1.2 Exposure Routes

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

11.1.3 Symptoms

Inhalation Exposure
Cough. Sore throat. Burning sensation. Shortness of breath.
Skin Exposure
MAY BE ABSORBED! Redness. Pain. Blisters.
Eye Exposure
Redness. Pain.
Ingestion Exposure
Metallic taste. Burning sensation. Nausea. Abdominal pain. Vomiting. Diarrhoea.

11.1.4 Adverse Effects

Neurotoxin - Sensorimotor

Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting.

Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects. See Guidelines for Reproductive Toxicity Risk Assessment.

11.1.5 Acute Effects

11.1.6 Antidote and Emergency Treatment

Basic Treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and neat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with available water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Mercury and related compounds/
Bronstein, A.C., P.L. Currance; Emergency Care for Hazardous Materials Exposure. 2nd ed. St. Louis, MO. Mosby Lifeline. 1994., p. 368-9
Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient with severe pulmonary edema or respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Mercury and related compounds/
Bronstein, A.C., P.L. Currance; Emergency Care for Hazardous Materials Exposure. 2nd ed. St. Louis, MO. Mosby Lifeline. 1994., p. 369
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat as necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 d of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Nitrates, nitrites, and related compounds/
Bronstein, A.C., P.L. Currance; Emergency Care for Hazardous Materials Exposure. 2nd ed. St. Louis, MO. Mosby Lifeline. 1994., p. 252
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Monitor cardiac rhythm and treat arrhythmias if necessary. Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present For hypotension with signs of hypovolemia, administer fluid cautiously. If unresponsive to these measures, vasopressors may be helpful. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Nitrates, nitrites, and related compounds/
Bronstein, A.C., P.L. Currance; Emergency Care for Hazardous Materials Exposure. 2nd ed. St. Louis, MO. Mosby Lifeline. 1994., p. 253

11.1.7 Non-Human Toxicity Excerpts

LETHAL DOSE FOR SINGLE IV INJECTION WAS APPROX 2.6 MG HG/KG OF MERCURIC NITRATE IN WHITE LEGHORN COCKS. WHEAT FEED TREATED WITH MERCURIC NITRATE CAUSED WT LOSS DURING 1ST 3 WK OF FEEDING. ...
SWENSSON A, ULFVARSON U; POULTRY SCI 48 (5): 1567-76 (1969)
Lebistes reticulatus were exposed 18 days to 25, 50 or 100 ppb (203) mercuric nitrate. Females had lower mortality and accumulated less mercury (Hg) (in 100 ppb solution, maximum body concn of mercury was approx 35 ppm on day 7 and 8) than males (maximum body concn of mercury was approx 40 ppm on day 5 and 6. After approx 14 days, Hg content in the fish decreased to a plateau of approx 20 ppm. Similar pattern was observed in fish exposed to 25 and 50 ppb mercury.
Rodrigues NS, Ferreira JR; Energ Nucl Agric 6 (2): 104-19 (1984)
The effect of inorganic compounds on liver injury resulting from disorders of carbohydrate metabolism was investigated. Male albino-rats, 90 days old, were divided into ten groups of ten rats. Rats were acclimated to laboratory conditions before they were fed sublethal doses of mercury-nitrate ... for 30 days. Rats were fasted overnight before sacrifice. Body/liver weight ratios were recorded, and thin slices of liver were removed for determination of glycogen. Mercuric nitrate caused depletion of glycogen in the liver.
Rana SVS et al; Toxicol Lett 29 (1): 1-4 (1985)
Acute toxicity studies with several mono-and divalent Mercury (Hg) in rats and mice by different administration routes (oral, cutaneous, and ip) indicated that mercuric chloride (Hg2C12) (via stomach in mice), and mercuric nitrate (Hg2(NO3)2) (ip in mice) were most toxic among Hg+ cmpd. Hg2+ cmpd were more toxic than the Hg+ cmpd. The effect of anion on the toxicity of the cmpd was more evident in Hg2+ subgroup.
Korshun MN; Gig Sanit 10: 79-80 (1985)
... /Some/ ointments contain ... mercuric nitrate (Hg(HNO3)2.2H2O). ... Dogs & cats are particularly susceptible to toxic effects of mercury from mercurial ointments, due to both direct absorption & to licking of parts to which the ointment has been applied. Poisoning in cattle has also been recorded after use of ointments containing ... mercuric nitrate. ... The sensitivity ... /of sheep & cattle/ is so great that fatal cases of poisoning have occurred as result of treatment, with ointments containing mercury, of other animals kept in the same house.
Clarke, M. L., D. G. Harvey and D. J. Humphreys. Veterinary Toxicology. 2nd ed. London: Bailliere Tindall, 1981., p. 61

11.2 Ecological Information

11.2.1 ICSC Environmental Data

The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in aquatic organisms. It is strongly advised not to let the chemical enter into the environment because it is persistent.

11.2.2 Probable Routes of Human Exposure

Although mercuric nitrate was the material used to treat fur from which felt was made /in the fur-cutting and felt-hat industries/, the mercury was gradually released from the fur amd felt in the form of metalic mercury vapor. Thus the workers had a mixed exposure to dust of mercury compounds (esp nitrate) & to vapor of the element.
Hayes, Wayland J., Jr. Pesticides Studied in Man. Baltimore/London: Williams and Wilkins, 1982., p. 12

12 Literature

12.1 Consolidated References

12.2 NLM Curated PubMed Citations

12.3 Springer Nature References

12.4 Thieme References

12.5 Wiley References

12.6 Chemical Co-Occurrences in Literature

12.7 Chemical-Gene Co-Occurrences in Literature

12.8 Chemical-Disease Co-Occurrences in Literature

13 Patents

13.1 Depositor-Supplied Patent Identifiers

13.2 WIPO PATENTSCOPE

13.3 Chemical Co-Occurrences in Patents

13.4 Chemical-Disease Co-Occurrences in Patents

13.5 Chemical-Gene Co-Occurrences in Patents

14 Interactions and Pathways

14.1 Chemical-Target Interactions

15 Classification

15.1 MeSH Tree

15.2 ChemIDplus

15.3 CAMEO Chemicals

15.4 UN GHS Classification

15.5 NORMAN Suspect List Exchange Classification

15.6 EPA DSSTox Classification

15.7 EPA TSCA and CDR Classification

15.8 EPA Substance Registry Services Tree

16 Information Sources

  1. Australian Industrial Chemicals Introduction Scheme (AICIS)
    Nitric acid, mercury(2+) salt, hemihydrate
    https://services.industrialchemicals.gov.au/search-inventory/
  2. CAMEO Chemicals
    LICENSE
    CAMEO Chemicals and all other CAMEO products are available at no charge to those organizations and individuals (recipients) responsible for the safe handling of chemicals. However, some of the chemical data itself is subject to the copyright restrictions of the companies or organizations that provided the data.
    https://cameochemicals.noaa.gov/help/reference/terms_and_conditions.htm?d_f=false
    CAMEO Chemical Reactivity Classification
    https://cameochemicals.noaa.gov/browse/react
  3. ChemIDplus
    ChemIDplus Chemical Information Classification
    https://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
  4. EPA Chemicals under the TSCA
    Nitric acid, mercury(2+) salt (2:1)
    https://www.epa.gov/chemicals-under-tsca
    EPA TSCA Classification
    https://www.epa.gov/tsca-inventory
  5. EPA DSSTox
    CompTox Chemicals Dashboard Chemical Lists
    https://comptox.epa.gov/dashboard/chemical-lists/
  6. European Chemicals Agency (ECHA)
    LICENSE
    Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.
    https://echa.europa.eu/web/guest/legal-notice
  7. FDA Global Substance Registration System (GSRS)
    LICENSE
    Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.
    https://www.fda.gov/about-fda/about-website/website-policies#linking
  8. Hazardous Substances Data Bank (HSDB)
  9. ILO-WHO International Chemical Safety Cards (ICSCs)
  10. New Zealand Environmental Protection Authority (EPA)
    LICENSE
    This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International licence.
    https://www.epa.govt.nz/about-this-site/general-copyright-statement/
  11. NJDOH RTK Hazardous Substance List
    mercuric nitrate see fact sheet # 1183 on mercury, elemental and inorganic compounds
    http://nj.gov/health/eoh/rtkweb/documents/fs/1173.pdf
  12. Emergency Response Guidebook (ERG)
  13. Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
    LICENSE
    Copyright (c) 2022 Haz-Map(R). All rights reserved. Unless otherwise indicated, all materials from Haz-Map are copyrighted by Haz-Map(R). No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.
    https://haz-map.com/About
  14. Comparative Toxicogenomics Database (CTD)
    LICENSE
    It is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.
    http://ctdbase.org/about/legal.jsp
  15. NITE-CMC
    mercury dinitrate - FY2006 (New/original classication)
    https://www.chem-info.nite.go.jp/chem/english/ghs/06-imcg-1046e.html
  16. SpectraBase
  17. Springer Nature
  18. Thieme Chemistry
    LICENSE
    The Thieme Chemistry contribution within PubChem is provided under a CC-BY-NC-ND 4.0 license, unless otherwise stated.
    https://creativecommons.org/licenses/by-nc-nd/4.0/
  19. Wikidata
  20. Wikipedia
  21. Wiley
  22. PubChem
  23. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
  24. GHS Classification (UNECE)
  25. NORMAN Suspect List Exchange
    LICENSE
    Data: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0
    https://creativecommons.org/licenses/by/4.0/
    NORMAN Suspect List Exchange Classification
    https://www.norman-network.com/nds/SLE/
  26. EPA Substance Registry Services
  27. PATENTSCOPE (WIPO)
  28. NCBI
CONTENTS