Melphalan Flufenamide Hydrochloride
- Melflufen hydrochloride
- 380449-54-7
- J-1 hydrochloride
- Pepaxto
- Melphalan flufenamide hydrochloride
- Create:2012-12-03
- Modify:2025-01-18
- melflufen
- melphalan-flufenamide
- pepaxto
- Melflufen hydrochloride
- 380449-54-7
- J-1 hydrochloride
- Pepaxto
- Melphalan flufenamide hydrochloride
- J1 hydrochloride
- Melflufen (hydrochloride)
- Melphalan-flufenamide
- UNII-3412470A0V
- 3412470A0V
- CK 1535
- CK-1535
- Melphalan flufenamide hydrochloride [USAN]
- Melphalanyl-p-L-fluorophenylalanine ethyl ester hydrochloride
- ethyl (2S)-2-[[(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoyl]amino]-3-(4-fluorophenyl)propanoate;hydrochloride
- L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-L-phenylalanyl-4-fluoro-, ethyl ester, monohydrochloride
- ETHYL (2S)-2-((2S)-2-AMINO-3-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)PROPANAMIDO)-3-(4-FLUOROPHENYL)PROPANOATE, HYDROCHLORIDE (1:1)
- Melphalan flufenamide hydrochloride (USAN)
- Pepaxti (TN)
- Pepaxto (TN)
- CHEMBL4297403
- AKOS040758099
- HY-105019A
- DA-75402
- MS-29889
- CS-0131562
- D11870
- G17559
- MELPHALAN FLUFENAMIDE HYDROCHLORIDE [WHO-DD]
- MELPHALAN FLUFENAMIDE HYDROCHLORIDE [ORANGE BOOK]
H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H340 (100%): May cause genetic defects [Danger Germ cell mutagenicity]
H350 (100%): May cause cancer [Danger Carcinogenicity]
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P264, P270, P280, P301+P316, P302+P352, P318, P321, P330, P332+P317, P362+P364, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Acute Tox. 2 (100%)
Skin Irrit. 2 (100%)
Muta. 1B (100%)
Carc. 1B (100%)
Repr. 2 (100%)
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=ZCMWSKHHXLCVHI-VROPFNGYSA-N
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.html
- ChemIDplusMelphalan flufenamide hydrochloride [USAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0380449547ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-noticeEthyl (2S)-2-[[(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoyl]amino]-3-(4-fluorophenyl)propanoate hydrochloridehttps://echa.europa.eu/substance-information/-/substanceinfo/100.252.189Ethyl (2S)-2-[[(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoyl]amino]-3-(4-fluorophenyl)propanoate hydrochloride (EC: 817-853-7)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/259949
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingMELPHALAN FLUFENAMIDE HYDROCHLORIDEhttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/3412470A0V
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- EU Clinical Trials Register
- European Medicines Agency (EMA)LICENSEInformation on the European Medicines Agency's (EMA) website is subject to a disclaimer and copyright and limited reproduction notices.https://www.ema.europa.eu/en/about-us/legal-noticePepaxti (EMEA/H/C/005681)https://www.ema.europa.eu/en/medicines/human/EPAR/pepaxti
- Open TargetsLICENSEDatasets generated by the Open Targets Platform are freely available for download.https://platform-docs.opentargets.org/licenceMELPHALAN FLUFENAMIDE HYDROCHLORIDEhttps://platform.opentargets.org/drug/CHEMBL4297403
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.htmlAnatomical Therapeutic Chemical (ATC) classificationhttp://www.genome.jp/kegg-bin/get_htext?br08303.keg
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuseNCI Thesaurushttps://ncit.nci.nih.gov
- Wikidatamelphalan flufenamide hydrochloridehttps://www.wikidata.org/wiki/Q120177846
- PubChem
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.html
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 395491594https://pubchem.ncbi.nlm.nih.gov/substance/395491594