Degarelix Acetate
- Degarelix acetate
- 934016-19-0
- Gonax
- ASP3550
- UNII-EXT215F4ZU
- Create:2007-07-04
- Modify:2025-01-11
- Ac-2Nal-4Cpa-3Pal-Ser-4Aph(hydroorotyl)-4Aph(carbamoyl)-Leu-ILys-pro-Ala-NH2
- acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide
- degarelix
- degarelix acetate
- FE 200486
- FE-200486
- FE200486
- Firmagon
- Gonax
- uglypeptide1
- Degarelix acetate
- 934016-19-0
- Gonax
- ASP3550
- UNII-EXT215F4ZU
- EXT215F4ZU
- Firmagon
- Degarelix monoacetate
- FE 200486
- FE-200486
- Degarelix (as acetate)
- Degarelix acetate hydrate
- DEGARELIX ACETATE ANHYDROUS
- DEGARELIX MONOACETATE ANHYDROUS
- N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide,monoacetate
- 934246-14-7
- D-Alaninamide, N-acetyl-3-(naphtalen-2-yl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-4-((((4S)-2,6-dioxohexahydropyrimidin-4-yl)carbonyl)amino)-L-phenylalanyl-4-(carbamoylamino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1)
- DEGARELIX ACETATE (MART.)
- I18S89P20R
- FE200486 (free base)
- Degarelix (acetate)
- N-ACETYL-3-(NAPHTHALEN-2-YL)-D-ALANYL-4-CHLORO-D-PHENYLALANYL-3-(PYRIDIN-3-YL)-D-ALANYL-L-SERYL-4-((((4S)-2,6-DIOXOHEXAHYDROPYRIMIDIN-4-YL)CARBONYL)AMINO)-L-PHENYLALANYL-4-(CARBAMOYLAMINO)-D-PHENYLALANYL-L-LEUCYL-N6-(1-METHYLETHYL)-L-LYSYL-L-PROLYL-D-ALANINAMIDE ACETATE HYDRATE
- FE200486 Acetate Hydrate
- CHEMBL2028987
- DTXSID201027699
- 214766-78-6 , Degarelix
- ASP-3550
- MFCD16879085
- AKOS040732946
- T10988L
- Degarelix (acetate) pound>>FE 200486
- HY-16168
- TS-07769
- Degarelix acetate(214766-78-6 free base)
- Q27277419
- D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-((((4S)-hexahydro-2,6-dioxo-4-pyrimidinyl)carbonyl)amino)-L-phenylalanyl-4-((aminocarbonyl)amino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl, Acetate, Hydrate
- N-Acetyl-3-(naphthalen-2-yl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-4-((((4S)-2,6-dioxohexahydropyrimidin-4-yl)carbonyl)amino)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide acetate
Degarelix is approved to treat:
• Prostate cancer that is advanced.
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]
P203, P261, P264, P270, P271, P280, P301+P317, P304+P340, P318, P319, P330, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Acute Tox. 4 (100%)
STOT SE 3 (100%)
Repr. 1B (100%)
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- ChemIDplusChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- EPA DSSToxDegarelix acetatehttps://comptox.epa.gov/dashboard/DTXSID201027699CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice[No public or meaningful name is available]https://echa.europa.eu/substance-information/-/substanceinfo/100.235.272(4S)-N-{4-[(2S,5S,8R,11R,14R)-2-({(2R)-1-{[(2S)-1-{[(2S)-1-[(2S)-2-{[(2R)-1-Amino-1-oxo-2-propanyl]carbamoyl}-1-pyrrolidinyl]-6-(isopropylamino)-1-oxo-2-hexanyl]amino}-4-methyl-1-oxo-2-pentanyl]amino} -3-[4-(carbamoylamino)phenyl]-1-oxo-2-propanyl}carbamoyl)-11-(4-chlorobenzyl)-5-(hydroxymethyl)-14-(2-naphthylmethyl)-4,7,10,13,16-pentaoxo-8-(3-pyridinylmethyl)-3,6,9,12,15-pentaazaheptadec-1-yl]phen yl}-2,6-dioxohexahydro-4-pyrimidinecarboxamihttps://echa.europa.eu807-570-7https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/244404(4S)-N-{4-[(2S,5S,8R,11R,14R)-2-({(2R)-1-{[(2S)-1-{[(2S)-1-[(2S)-2-{[(2R)-1-Amino-1-oxo-2-propanyl]carbamoyl}-1-pyrrolidinyl]-6-(isopropylamino)-1-oxo-2-hexanyl]amino}-4-methyl-1-oxo-2-pentanyl]amino} -3-[4-(carbamoylamino)phenyl]-1-oxo-2-propanyl}carbamoyl)-11-(4-chlorobenzyl)-5-(hydroxymethyl)-14-(2-naphthylmethyl)-4,7,10,13,16-pentaoxo-8-(3-pyridinylmethyl)-3,6,9,12,15-pentaazaheptadec-1-yl]phen yl}-2,6-dioxohexahydro-4-pyrimidinecarboxami (EC: 112-301-5)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/398271
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingDEGARELIX ACETATE ANHYDROUShttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/EXT215F4ZU
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
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- European Medicines Agency (EMA)LICENSEInformation on the European Medicines Agency's (EMA) website is subject to a disclaimer and copyright and limited reproduction notices.https://www.ema.europa.eu/en/about-us/legal-noticeDegarelix Accord (EMEA/H/C/006048)https://www.ema.europa.eu/en/medicines/human/EPAR/degarelix-accordFirmagon (EMEA/H/C/000986)https://www.ema.europa.eu/en/medicines/human/EPAR/firmagon
- EU Clinical Trials Register
- FDA Orange BookLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- Open TargetsLICENSEDatasets generated by the Open Targets Platform are freely available for download.https://platform-docs.opentargets.org/licenceDEGARELIX ACETATEhttps://platform.opentargets.org/drug/CHEMBL2028987
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.html
- NCI Cancer Drugs
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuseNCI Thesaurushttps://ncit.nci.nih.gov
- Therapeutic Target Database (TTD)
- Wikidatadegarelix acetatehttps://www.wikidata.org/wiki/Q27277419
- PubChem
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlacetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamidehttps://www.ncbi.nlm.nih.gov/mesh/67431566
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- NCBI