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CID 24197163

PubChem CID
24197163
Structure
CID 24197163_small.png
CID 24197163_3D_Structure.png
Molecular Formula
Synonyms
  • Troclosene potassium
  • 2244-21-5
  • SCHEMBL305053
  • AKOS040746424
Molecular Weight
237.06 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Parent Compound
Dates
  • Create:
    2008-02-29
  • Modify:
    2025-01-04
Description
Potassium dichloro-s-triazinetrione, dry is a white solid with an odor of chlorine. Mixes with water. (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.

1 Structures

1.1 2D Structure

Chemical Structure Depiction
CID 24197163.png

1.2 3D Conformer

3D Conformer of Parent

2 Names and Identifiers

2.1 Computed Descriptors

2.1.1 InChI

InChI=1S/C3HCl2N3O3.K/c4-7-1(9)6-2(10)8(5)3(7)11;/h(H,6,9,10);
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

2.1.2 InChIKey

UGLFQJOXHCQGFQ-UHFFFAOYSA-N
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

2.1.3 SMILES

C1(=O)NC(=O)N(C(=O)N1Cl)Cl.[K]
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)

2.2 Molecular Formula

C3HCl2N3O3.K
C3HCl2KN3O3
Computed by PubChem 2.2 (PubChem release 2021.10.14)

2.3 Other Identifiers

2.3.1 CAS

2244-21-5

2.3.2 Deprecated CAS

14426-07-4, 156620-80-3, 174016-61-6, 25727-26-8, 57073-47-9, 68462-52-2, 73694-07-2

2.3.3 European Community (EC) Number

2.3.4 UN Number

2.3.5 KEGG ID

2.3.6 NCI Thesaurus Code

2.3.7 Wikidata

2.4 Synonyms

2.4.1 Depositor-Supplied Synonyms

3 Chemical and Physical Properties

3.1 Computed Properties

Property Name
Molecular Weight
Property Value
237.06 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Donor Count
Property Value
1
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Acceptor Count
Property Value
3
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Rotatable Bond Count
Property Value
0
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Exact Mass
Property Value
235.9032028 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Monoisotopic Mass
Property Value
235.9032028 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Topological Polar Surface Area
Property Value
69.7Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Heavy Atom Count
Property Value
12
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
220
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
2
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)

3.2 Experimental Properties

3.2.1 Physical Description

Potassium dichloro-s-triazinetrione, dry is a white solid with an odor of chlorine. Mixes with water. (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
White solid; Slightly hygroscopic; [Hawley] White crystalline solid; [MSDSonline]

3.2.2 Color / Form

WHITE, CRYSTALLINE POWDER OR GRANULES
Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 952

3.2.3 Odor

Chlorine-like
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Manual Two. Washington, DC: U.S. Government Printing Office, Oct., 1978.

3.2.4 Melting Point

482 °F (decomposes) (NTP, 1992)
National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.

3.2.5 Solubility

10 to 50 mg/mL at 63 °F (NTP, 1992)
National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.

3.2.6 Density

0.96 at 68 °F (USCG, 1999) - Less dense than water; will float
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
0.96 at 20 °C (solid)
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Manual Two. Washington, DC: U.S. Government Printing Office, Oct., 1978.
LOOSE BULK DENSITY (APPROX) POWDER 37 LB/CU FT; GRANULAR 64 LB/CU FT; ACTIVE INGREDIENT APPROX 59% AVAILABLE CHLORINE; DECOMPOSES AT 240 °C; SLIGHTLY HYGROSCOPIC
Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 952

3.3 Chemical Classes

Other Uses -> Biocides/Disinfectants

3.3.1 Cosmetics

Antimicrobial; Oxidising
S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118

5 Chemical Vendors

6 Drug and Medication Information

6.1 Reported Fatal Dose

3. 3= Moderately toxic: Probable oral lethal dose (human) 0.5-5 g/kg; between 1 oz & 1 pint (or 1 lb) for 70 kg (150 lb) person. /Trichloroisocyanuric Acid/
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-111

7 Agrochemical Information

7.1 Agrochemical Category

Microbiocide

8 Use and Manufacturing

8.1 Uses

Sources/Uses
Used as sanitizer in water treatment (especially swimming pools), as a bleach and sanitizer in cleaners and laundry products, as a chlorinating agent to prepare wool for printing, and as a topical anti-infective; [HSDB]
Industrial Processes with risk of exposure
SANITIZER IN WATER TREATMENT, ESP FOR SWIMMING POOLS; BLEACH & SANITIZER IN HOUSEHOLD, INDUST LAUNDRY PRODUCTS & IN OTHER CLEANING PRODUCTS; CHLORINATING AGENT IN THE PREPN OF WOOL FOR PRINTING; CHEM INT FOR COMPLEX WITH TRICHLOROISOCYANURIC ACID; TOPICAL ANTIINFECTIVE
SRI
Household dry bleaches, dishwashing compounds, scouring compounds, detergent sanitizers, replacement for calcium hypochlorite.
Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 952

8.1.1 Use Classification

Hazard Classes and Categories -> Reactive - 2nd degree
Cosmetics -> Antimicrobial; Oxidising
S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118

8.2 Methods of Manufacturing

...FROM TRISODIUM ISOCYANURATE AND GASEOUS CHLORINE.
The Merck Index. 10th ed. Rahway, New Jersey: Merck Co., Inc., 1983., p. 1395
CHLORINATION OF DISODIUM CYANURATE TO FORM DICHLOROISOCYANURIC ACID FOLLOWED BY NEUTRALIZATION WITH POTASSIUM HYDROXIDE & CRYSTALLIZATION
SRI

8.3 Formulations / Preparations

Grades or Purity: Technical: 39-59% available chlorine.
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Manual Two. Washington, DC: U.S. Government Printing Office, Oct., 1978.

8.4 U.S. Production

(1978) 3.5X10+10 G (TOTAL, DCCA & SALTS)
SRI
(1981) 3.6X10+10 G (TOTAL, DCCA & SALTS)
SRI

8.5 General Manufacturing Information

EPA TSCA Commercial Activity Status
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt (1:1): ACTIVE

9 Safety and Hazards

9.1 Hazards Identification

9.1.1 GHS Classification

1 of 2
View All
Pictogram(s)
Oxidizer
Corrosive
Irritant
Environmental Hazard
Signal
Danger
GHS Hazard Statements

H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H332: Harmful if inhaled [Warning Acute toxicity, inhalation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statement Codes

P210, P220, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P370+P378, P391, P403+P233, P405, and P501

(The corresponding statement to each P-code can be found at the GHS Classification page.)

9.1.2 Hazard Classes and Categories

Acute toxicity - category 4

Acute toxicity - category 4

Skin irritation - category 2

Eye damage - category 1

Specific target organ toxicity (single exposure) - category 3

Oxidising solid - category 2

Hazardous to the aquatic environment (chronic) - category 1

Hazardous to the aquatic environment (acute) - category 1

Reactive - 2nd degree

9.1.3 NFPA Hazard Classification

NFPA 704 Diamond
3-0-2- ̵W̵
NFPA Health Rating
3 - Materials that, under emergency conditions, can cause serious or permanent injury.
NFPA Fire Rating
0 - Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand.
NFPA Instability Rating
2 - Materials that readily undergo violent chemical changes at elevated temperatures and pressures.
NFPA Specific Notice
W - No water: Materials that react violently or explosively with water.

9.1.4 Health Hazards

Dust causes sneezing and coughing; is moderately irritating to the eyes and causes itching and redness of skin. Ingestion causes burns of mouth and stomach. (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.

9.1.5 Fire Hazards

Special Hazards of Combustion Products: May form toxic chlorine and other gases in fire

Behavior in Fire: Decomposition can be initiated with a heat source and can propagate throughout the mass with the evolution of dense fumes. Containers may explode when heated. (USCG, 1999)

U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.

9.1.6 Hazards Summary

A strong oxidizer; Poses dangerous fire risk on contact with organic substances; [Hawley] A skin, eye, nose, and throat irritant; [HSDB] A strong oxidizing agent; May react with water producing chlorine gas; A moderate eye irritant; [CAMEO] A skin and eye irritant (heavy exposures may cause corrosive injury); Inhalation of very high concentrations may cause pulmonary edema; [CHEMINFO] An eye and respiratory tract irritant; [eChemPortal: ESIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; Causes lacrimation and sneezing; [MSDSonline] See Sodium dichloroisocyanurate.
Hawley - Lewis RJ. _Hawley's Condensed Chemical Dictionary, _15th Ed. New York: John Wiley & Sons, 2007.

9.1.7 Fire Potential

The material itself is noncombustible but if contaminated with a combustible material ignition can result. It will accelerate the burning of combustible materials. /Dichloroisocyanuric acid, dry or salts/
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 354

9.1.8 Skin, Eye, and Respiratory Irritations

Dust: Irritating to eyes, nose and throat. If inhaled will cause coughing or difficult breathing. Solid: Irritating to skin and eyes.
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Manual Two. Washington, DC: U.S. Government Printing Office, Oct., 1978.

9.2 First Aid Measures

9.2.1 First Aid

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.

9.3 Fire Fighting

Fire Extinguishing Agents: Water (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.

9.3.1 Fire Fighting Procedures

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Dichloroisocyanuric acid, dry or salts/
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 354
If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius. /Dichloroisocyanuric acid, dry or salts/
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 354
Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Fight fire from protected location or maximum possible distance. Use remote equipment whenever possible. Use flooding quantities of water or fire-involved containers. If necessary use water spray to keep fire-exposed containers cool.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 49-112

9.4 Accidental Release Measures

9.4.1 Isolation and Evacuation

Excerpt from ERG Guide 140 [Oxidizers]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. If ammonium nitrate products are in a tank, rail car or truck and involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions. (ERG, 2024)

9.4.2 Cleanup Methods

Keep water away from release. Approach release from upwind. Isolate leaking containers, if this can be done without undue risk. Prompt cleanup and removal are necessary. Do not create dust. Shovel into suitable dry container. Control run-off and isolate discharge material for proper disposal.
National Fire Protection Guide. Fire Protection Guide on Hazardous Materials. 10 th ed. Quincy, MA: National Fire Protection Association, 1991., p. 49-144

9.4.3 Disposal Methods

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

9.4.4 Preventive Measures

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. /Dichloroisocyanuric acid, dry or salts/
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 354
Personnel protection: .. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material is anticipated, wear appropriate chemical protective clothing. Approach fire with caution. /Dichloroisocyanuric acid, dry or salts/
Association of American Railroads. Emergency Handling of Hazardous Materials in Surface Transportation. Washington, DC: Association of American Railroads, Bureau of Explosives, 1994., p. 354
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

9.5 Handling and Storage

9.5.1 Nonfire Spill Response

Excerpt from ERG Guide 140 [Oxidizers]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Do not get water inside containers.

SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

SMALL LIQUID SPILL: Use a non-combustible material like vermiculite or sand to soak up the product and place into a container for later disposal.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. (ERG, 2024)

9.5.2 Storage Conditions

Store in a cool, dry, well-ventilated location. Outside or detached storage is preferred. Must be stored in a dry location on pallets arranged according to NFPA 43A, Code for Storage of Liquid and Solid Oxidizers. Separate from combustible, oxidizing materials, ammonia, sodium carbonate (soda ash), calcium hypochlorite, hydrogen peroxide.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 49-112

9.6 Exposure Control and Personal Protection

9.6.1 Personal Protective Equipment (PPE)

Dust mask or chlorine canister mask; goggles; rubber gloves and other protective clothing to prevent contact with skin. (USCG, 1999)
U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
/SRP: NIOSH certified respirator/ or chlorine canister mask; goggles; rubbber gloves or other protective clothing to prevent contact with skin.
U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Manual Two. Washington, DC: U.S. Government Printing Office, Oct., 1978.

9.7 Stability and Reactivity

9.7.1 Air and Water Reactions

The solid may vigorously react with water releasing chlorine gas. Material containing less than 39% available chlorine will undergo reactions as described herein, but may take longer to initiate, and the resulting reaction may not be as vigorous. Water soluble.

9.7.2 Reactive Group

Salts, Acidic

Acyl Halides, Sulfonyl Halides, and Chloroformates

Oxidizing Agents, Strong

Halogenating Agents

9.7.3 Reactivity Alerts

Strong Oxidizing Agent

Water-Reactive

9.7.4 Reactivity Profile

Contact with ammonium compounds or hydrated salts can cause a very vigorous reaction. Prolonged exposure to heat /fire may result in the vigorous decomposition of the material with the rupture of its containers, it will accelerate the burning of combustible materials. Chlorine plus alcohols would yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites [NFPA 491 M. 1991].

9.7.5 Hazardous Reactivities and Incompatibilities

Contact with foreign materials, organic matter, or easily chlorinated or oxidized material may result in fire. Mixture with ammonium salts or similar nitrogen containing compounds may result in exothermic reactions, causing fire or explosion. Reacts with water to release chlorine gas and nitrogen trichloride and in confined spaces increased temperature and pressure to dangerous levels.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 49-112

9.8 Transport Information

9.8.1 DOT Emergency Guidelines

/GUIDE 140: OXIDIZERS/ Fire or Explosion: These substances will accelerate burning when involved in a fire. Some may decompose explosively when heated or involved in a fire. May explode from heat or contamination. Some will react explosively with hydrocarbons (fuels). May ignite combustibles (wood, paper, oil, clothing, etc.). Containers may explode when heated. Runoff may create fire or explosion hazard. /Dichloroisocyanuric acid salts/
U.S. Department of Transportation. 2004 Emergency Response Guidebook. A Guide book for First Responders During the Initial Phase of a Dangerous Goods/Hazardous Materials Incident. Washington, D.C. 2004
/GUIDE 140: OXIDIZERS/ Health: Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution. /Dichloroisocyanuric acid salts/
U.S. Department of Transportation. 2004 Emergency Response Guidebook. A Guide book for First Responders During the Initial Phase of a Dangerous Goods/Hazardous Materials Incident. Washington, D.C. 2004
/GUIDE 140: OXIDIZERS/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering. /Dichloroisocyanuric acid salts/
U.S. Department of Transportation. 2004 Emergency Response Guidebook. A Guide book for First Responders During the Initial Phase of a Dangerous Goods/Hazardous Materials Incident. Washington, D.C. 2004
/GUIDE 140: OXIDIZERS/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection. /Dichloroisocyanuric acid salts/
U.S. Department of Transportation. 2004 Emergency Response Guidebook. A Guide book for First Responders During the Initial Phase of a Dangerous Goods/Hazardous Materials Incident. Washington, D.C. 2004
For more DOT Emergency Guidelines (Complete) data for POTASSIUM DICHLOROISOCYANURATE (8 total), please visit the HSDB record page.

9.8.2 Shipping Name / Number DOT/UN/NA/IMO

9.8.3 Shipment Methods and Regulations

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
49 CFR 171.2 (7/1/96)
The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.
IATA. Dangerous Goods Regulations. 38th ed. Montreal, Canada and Geneva, Switzerland: International Air Transport Association, Dangerous Goods Board, January, 1997., p. 136
The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
IMDG; International Maritime Dangerous Goods Code; International Maritime Organization p.5039-1 (1988)

9.8.4 DOT Label

Oxidizer

9.9 Regulatory Information

The Australian Inventory of Industrial Chemicals
Chemical: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt
New Zealand EPA Inventory of Chemical Status
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt: Does not have an individual approval but may be used under an appropriate group standard

9.10 Other Safety Information

Chemical Assessment
IMAP assessments - Dichloroisocyanurates: Human health tier II assessment

9.10.1 Toxic Combustion Products

Products of combustion may be more hazardous than the material itself.
Fire Protection Guide to Hazardous Materials. 12 ed. Quincy, MA: National Fire Protection Association, 1997., p. 49-112

10 Toxicity

10.1 Toxicological Information

10.1.1 Adverse Effects

Dermatotoxin - Skin burns.

Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

10.1.2 Human Toxicity Excerpts

The toxicity is apparently due to corrosive action on stomach lining rather than to any systemic effects. In the presence of moisture, as in the eyes, upper respiratory tract or on moist or abraded skin, it is moderately irritating. In some individuals bronchospasm may result from breathing the dust. /Trichloroisocyanuric acid/
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-111

10.1.3 Non-Human Toxicity Excerpts

NO IRRITATION ON THE INTACT SKIN OF RABBITS WAS OBSERVED AFTER APPLICATION OF SODIUM (POTASSIUM) DICHLOROISOCYANURATE IN THE FORM OF DRY POWDER FOR 24 HR.
CANELLI E; AMER J PUB HEALTH 64 (2): 155 (1974)
NO SIGNIFICANT IRRITATION WAS REPORTED WHEN ONE EYE OF A RABBIT WAS EXPOSED TO SOLN OF POTASSIUM DICHLOROISOCYANURATE (3 PPM AS AVAILABLE CHLORINE) FLOWING AT APPROX 330 ML/HR, 1 HR/DAY, 5 DAYS/WK, FOR TOTAL OF 30 EXPOSURES.
CANELLI E; AMER J PUB HEALTH 64 (2): 155 (1974)

10.1.4 TSCA Test Submissions

Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for acute oral toxicity. The test substance was administered orally to Sprague-Dawley albino rats. Dosage levels and mortality data are as follows: 1000 (0/2 M, 1/3 F); 1260 (0/3 M, 2/2 F); 1580 (1/2 M, 3/3 F); and 2000 mg/kg of body weight (3/3 M, 2/2 F), with most deaths occurring within 2 days. Clinical signs included reduced appetite and activity, increasing weakness, collapse, and death. Necropsy findings revealed hemorrhagic areas of the lungs, liver discoloration, and acute gastrointestinal inflammation. The LD50 was determined to be 1400 mg/kg b.w.
MONSANTO CO; Initial Submission: Toxicological Investigation of: ACL-59N with Cover Letter Dated 08/13/92; 04/30/74; EPA Doc. No. 88-920007822; Fiche No. OTS0545967
Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for acute dermal toxicity. The test substance was applied to the skin of New Zealand albino rabbits for 24-hours. Dosage levels and mortality data are as follows: 1260 (0/1 M); 2000 (0/1 F); 3160 (1/1 M in 4-days); and 5010 mg/kg b.w. (1/1 F in 3-days). Clinical signs included reduced appetite and activity, increasing weakness, collapse, and death. Necropsy findings revealed hemorrhagic areas of the lungs and liver, enlarged gall bladder, and gastrointestinal inflammation. The LD50 was determined to be greater than 2,000 mg/kg b.w.
MONSANTO CO; Initial Submission: Toxicological Investigation of: ACL-59N with Cover Letter Dated 08/13/92; 04/30/74; EPA Doc. No. 88-920007822; Fiche No. OTS0545967
Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for eye irritation. The test substance was applied to the eyes of New Zealand white rabbits at a dose level of 100.0 mg of finely ground powder for 24-hours. Clinical signs included immediate discomfort, slight to moderate erythema which progressed to severe erythema within 24-hours, very slight edema, and a copious discharge which later contained a whitish exudate. At 48-hours there was gradual improvement. The test substance was determined to be a slight eye irritant.
MONSANTO CO; Initial Submission: Toxicological Investigation of: ACL-59N with Cover Letter Dated 08/13/92; 04/30/74; EPA Doc. No. 88-920007822; Fiche No. OTS0545967
Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for primary dermal irritation. The test substance was applied as a finely ground powder moistened with water to the skin of New Zealand albino rabbits at a dose level of 0.5 g for 24-hours. Clinical signs included very slight erythema and edema which progressed to corrosion within 24-hours. From 14-17 days, there was slight loosening about edges of scab showing injury in depth. The test substance was determined to be corrosive.
MONSANTO CO; Initial Submission: Toxicological Investigation of: ACL-59N with Cover Letter Dated 08/13/92; 04/30/74; EPA Doc. No. 88-920007822; Fiche No. OTS0545967

10.2 Ecological Information

10.2.1 EPA Ecotoxicity

Pesticide Ecotoxicity Data from EPA

10.2.2 Probable Routes of Human Exposure

Occupational exposure to potassium dichloroisocyanurate may occur through dermal contact or inhalation where this compound us produced or used. The general population will be exposed to potassium dichloroisocyanurate through dermal contact with this compound where it is used as a sanitizer in water treatment and household cleaning products. (SRC)

11 Literature

11.1 Consolidated References

12 Patents

12.1 Depositor-Supplied Patent Identifiers

12.2 Chemical Co-Occurrences in Patents

12.3 Chemical-Disease Co-Occurrences in Patents

12.4 Chemical-Gene Co-Occurrences in Patents

13 Classification

13.1 CAMEO Chemicals

13.2 UN GHS Classification

13.3 NORMAN Suspect List Exchange Classification

13.4 EPA TSCA and CDR Classification

14 Information Sources

  1. Australian Industrial Chemicals Introduction Scheme (AICIS)
    1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt
    https://services.industrialchemicals.gov.au/search-assessments/
    1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt
    https://services.industrialchemicals.gov.au/search-inventory/
  2. CAMEO Chemicals
    LICENSE
    CAMEO Chemicals and all other CAMEO products are available at no charge to those organizations and individuals (recipients) responsible for the safe handling of chemicals. However, some of the chemical data itself is subject to the copyright restrictions of the companies or organizations that provided the data.
    https://cameochemicals.noaa.gov/help/reference/terms_and_conditions.htm?d_f=false
    POTASSIUM DICHLORO-S-TRIAZINETRIONE, DRY
    https://cameochemicals.noaa.gov/chemical/9011
    CAMEO Chemical Reactivity Classification
    https://cameochemicals.noaa.gov/browse/react
  3. CAS Common Chemistry
    LICENSE
    The data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.
    https://creativecommons.org/licenses/by-nc/4.0/
  4. EPA Chemicals under the TSCA
    1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, potassium salt (1:1)
    https://www.epa.gov/chemicals-under-tsca
    EPA TSCA Classification
    https://www.epa.gov/tsca-inventory
  5. European Chemicals Agency (ECHA)
    LICENSE
    Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.
    https://echa.europa.eu/web/guest/legal-notice
  6. Hazardous Substances Data Bank (HSDB)
  7. New Zealand Environmental Protection Authority (EPA)
    LICENSE
    This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International licence.
    https://www.epa.govt.nz/about-this-site/general-copyright-statement/
  8. NJDOH RTK Hazardous Substance List
  9. Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
    LICENSE
    Copyright (c) 2022 Haz-Map(R). All rights reserved. Unless otherwise indicated, all materials from Haz-Map are copyrighted by Haz-Map(R). No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.
    https://haz-map.com/About
    Potassium dichloroisocyanurate
    https://haz-map.com/Agents/6793
  10. EPA Pesticide Ecotoxicity Database
  11. Hazardous Chemical Information System (HCIS), Safe Work Australia
  12. Regulation (EC) No 1272/2008 of the European Parliament and of the Council
    LICENSE
    The copyright for the editorial content of this source, the summaries of EU legislation and the consolidated texts, which is owned by the EU, is licensed under the Creative Commons Attribution 4.0 International licence.
    https://eur-lex.europa.eu/content/legal-notice/legal-notice.html
  13. KEGG
    LICENSE
    Academic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial license
    https://www.kegg.jp/kegg/legal.html
  14. NCI Thesaurus (NCIt)
    LICENSE
    Unless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.
    https://www.cancer.gov/policies/copyright-reuse
  15. NORMAN Suspect List Exchange
    LICENSE
    Data: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0
    https://creativecommons.org/licenses/by/4.0/
    NORMAN Suspect List Exchange Classification
    https://www.norman-network.com/nds/SLE/
  16. Wikidata
  17. PubChem
  18. GHS Classification (UNECE)
CONTENTS