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Zirconium picramate

PubChem CID
11979385
Structure
Zirconium picramate_small.png
Zirconium picramate_3D_Structure.png
Molecular Formula
Synonyms
  • Zirconium, tetrakis(2-amino-4,6-dinitrophenolato)-
  • ZIRCONIUM PICRAMATE
  • 63868-82-6
  • HSDB 1994
  • Picramic acid, zirconium salt (wet)
Molecular Weight
883.7 g/mol
Computed by PubChem 2.2 (PubChem release 2024.11.20)
Dates
  • Create:
    2007-01-09
  • Modify:
    2025-01-18
Description
Zirconium picramate appears as a solid or liquid. Primary hazard is fire with either a minor blast or projection hazard or both, but no mass explosion hazard. May explode under prolonged exposure to heat.
Zirconium picramate, wetted with not less than 20% water appears as a slurry or sludge of yellow crystals. May take some effort to ignite but once ignited burns with great rapidity. Accelerates the burning of combustible materials. If large quantities are involved in fire or if containers of the material are exposed to fire or heat for prolonged periods, an explosion may result. Produces toxic oxides of nitrogen during combustion.

1 Structures

1.1 2D Structure

Chemical Structure Depiction
Zirconium picramate.png

1.2 3D Conformer

3D Conformer of Parent

2 Names and Identifiers

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-4,6-dinitrophenolate;zirconium(4+)
Computed by Lexichem TK 2.7.0 (PubChem release 2024.11.20)

2.1.2 InChI

InChI=1S/4C6H5N3O5.Zr/c4*7-4-1-3(8(11)12)2-5(6(4)10)9(13)14;/h4*1-2,10H,7H2;/q;;;;+4/p-4
Computed by InChI 1.07.0 (PubChem release 2024.11.20)

2.1.3 InChIKey

SSGTYYSNZOGONL-UHFFFAOYSA-J
Computed by InChI 1.07.0 (PubChem release 2024.11.20)

2.1.4 SMILES

C1=C(C=C(C(=C1N)[O-])[N+](=O)[O-])[N+](=O)[O-].C1=C(C=C(C(=C1N)[O-])[N+](=O)[O-])[N+](=O)[O-].C1=C(C=C(C(=C1N)[O-])[N+](=O)[O-])[N+](=O)[O-].C1=C(C=C(C(=C1N)[O-])[N+](=O)[O-])[N+](=O)[O-].[Zr+4]
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)

2.2 Molecular Formula

C24H16N12O20Zr
Computed by PubChem 2.2 (PubChem release 2024.11.20)

2.3 Other Identifiers

2.3.1 CAS

63868-82-6

2.3.2 UNII

2.3.3 UN Number

2.3.4 DSSTox Substance ID

2.3.5 Nikkaji Number

2.3.6 Wikidata

2.4 Synonyms

2.4.1 Depositor-Supplied Synonyms

3 Chemical and Physical Properties

3.1 Computed Properties

Property Name
Molecular Weight
Property Value
883.7 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2024.11.20)
Property Name
Hydrogen Bond Donor Count
Property Value
4
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2024.11.20)
Property Name
Hydrogen Bond Acceptor Count
Property Value
24
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2024.11.20)
Property Name
Rotatable Bond Count
Property Value
0
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2024.11.20)
Property Name
Exact Mass
Property Value
881.965080 Da
Reference
Computed by PubChem 2.2 (PubChem release 2024.11.20)
Property Name
Monoisotopic Mass
Property Value
881.965080 Da
Reference
Computed by PubChem 2.2 (PubChem release 2024.11.20)
Property Name
Topological Polar Surface Area
Property Value
563 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2024.11.20)
Property Name
Heavy Atom Count
Property Value
57
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
247
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2024.11.20)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
5
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)

3.2 Experimental Properties

3.2.1 Physical Description

Zirconium picramate appears as a solid or liquid. Primary hazard is fire with either a minor blast or projection hazard or both, but no mass explosion hazard. May explode under prolonged exposure to heat.
Zirconium picramate, wetted with not less than 20% water appears as a slurry or sludge of yellow crystals. May take some effort to ignite but once ignited burns with great rapidity. Accelerates the burning of combustible materials. If large quantities are involved in fire or if containers of the material are exposed to fire or heat for prolonged periods, an explosion may result. Produces toxic oxides of nitrogen during combustion.
Flammable solid; [NJ-HSFS]

3.2.2 Stability / Shelf Life

...A number of explosive properties of these picramates point to the fact that the zirconium picramate is thermally more stable than the picramates of titanium and thorium.
Srivastava RS et al; Propellants, Explosives, Pyrotechnics 1 (5-6): 101-103 (2004)

3.2.3 Decomposition

When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 2703

3.3 Chemical Classes

Metals -> Organic Acids, Metal Salts

5 Chemical Vendors

6 Use and Manufacturing

6.1 Uses

Sources/Uses
Used as a medication; [HSDB]

6.2 Methods of Manufacturing

Picramate of ... zirconium ... /is/ prepared by treating the aqueous sulfate, chloride and nitrate solutions with sodium picramate.
Srivastava RS et al; Propellants, Explosives, Pyrotechnics 1 (5-6): 101-103 (2004)

6.3 U.S. Production

(1977) NOT PRODUCED COMMERCIALLY IN USA
SRI
(1979) NOT PRODUCED COMMERCIALLY IN USA
SRI

6.4 General Manufacturing Information

Naturally occurring zirconium contains five isotopes. Thirty-one other radioactive isotopes and isomers are known to exist.
Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 94th Edition. CRC Press LLC, Boca Raton: FL 2013-2014, p. 4-42

7 Identification

7.1 Analytic Laboratory Methods

Micro-analysis, colorimetry and spectrophotometry are used to establish the compositions (metal : ligand ratio) of these picramates as 1:2 (for ... zirconium) ...
Srivastava RS et al; Propellants, Explosives, Pyrotechnics 1 (5-6): 101-103 (2004)

8 Safety and Hazards

8.1 Hazards Identification

8.1.1 GHS Classification

Pictogram(s)
Explosive
Irritant
Signal
Danger
GHS Hazard Statements

H203: (Deleted) Explosive; fire, blast or projection hazard [Danger Explosives]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statement Codes

P210, P230, P240, P250, P261, P271, P280, P304+P340, P319, P370+P380, P372, P373, P401, P403+P233, P405, and P501

(The corresponding statement to each P-code can be found at the GHS Classification page.)

8.1.2 Hazard Classes and Categories

Explosives - Division 1.3

Specific target organ toxicity - Single exposure - Category 3 (Respiratory tract irritation)

8.1.3 Health Hazards

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

Fire may produce irritating, corrosive and/or toxic gases. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

Some are toxic and may be fatal if inhaled, ingested or absorbed through skin. Specifically, Dinitrophenol, wetted (UN1320); Dinitrophenolates, wetted (UN1321), Sodium dinitro-o-cresolate, wetted (UN1348); and Barium azide, wetted (UN1571) are known to be toxic. Contact may cause burns to skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause environmental contamination. (ERG, 2024)

ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

· Some are toxic and may be fatal if inhaled, ingested or absorbed through skin. Specifically, Dinitrophenol, wetted (UN1320); Dinitrophenolates, wetted (UN1321), Sodium dinitro-o-cresolate, wetted (UN1348); and Barium azide, wetted (UN1571) are known to be toxic.

· Contact may cause burns to skin and eyes.

· Fire may produce irritating, corrosive and/or toxic gases.

· Runoff from fire control or dilution water may cause environmental contamination.

8.1.4 Fire Hazards

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

MAY EXPLODE AND THROW FRAGMENTS 1600 METERS (1 MILE) OR MORE IF FIRE REACHES CARGO. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; treat as an explosive (ERG Guide 112). Keep material wet with water or treat as an explosive (ERG Guide 112). Runoff to sewer may create fire or explosion hazard. (ERG, 2024)

ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

· Flammable/combustible material.

· May be ignited by heat, sparks or flames.

· DRIED OUT material may explode if exposed to heat, flame, friction or shock; treat as an explosive (GUIDE 112).

· Keep material wet with water or treat as an explosive (GUIDE 112).

· Runoff to sewer may create fire or explosion hazard.

8.1.5 Hazards Summary

Can cause skin burns and allergic skin reactions; An explosion hazard when dry or wetted with less than 20% water; [NJ-HSFS] See Zirconium.

8.2 Safety and Hazard Properties

8.2.1 OSHA Standards

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 5 mg/cu m. /Zirconium compounds (as Zr)/
29 CFR 1910.1000 (USDOL); U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of April 7, 2015: https://www.ecfr.gov
Vacated 1989 OSHA PEL TWA 5 mg/cu m; STEL 10 mg/cu m is still enforced in some states. /Zirconium compounds (as Zr)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 374

8.2.2 NIOSH Recommendations

Recommended Exposure Limit: 10 Hour Time-Weighted Average: 5 mg/cu m /Zirconium compounds (as Zr)/ [Note: The REL applies to all zirconium compounds (as Zr) except zirconium tetrachloride.]
NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg
Recommended Exposure Limit: 15 Minute Short Term Exposure Limit: 10 mg/cu m /Zirconium compounds (as Zr)/ [Note: The REL applies to all zirconium compounds (as Zr) except Zirconium tetrachloride.]
NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg

8.3 First Aid Measures

8.3.1 First Aid

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

Refer to the "General First Aid" section. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

Refer to the "General First Aid" section. (ERG, 2024)

ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingestedor inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuouscompressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

8.4 Fire Fighting

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

CARGO FIRE: DO NOT fight fire when fire reaches cargo! Cargo may EXPLODE! Stop all traffic and clear the area for at least 1600 meters (1 mile) in all directions and let burn. Do not move cargo or vehicle if cargo has been exposed to heat.

TIRE OR VEHICLE FIRE: Use plenty of water - FLOOD it! If water is not available, use CO2, dry chemical or dirt. If possible, and WITHOUT RISK, use unmanned master stream devices or monitor nozzles from maximum distance to prevent fire from spreading to cargo area. Pay special attention to tire fires as re-ignition may occur. Stand by, at a safe distance, with extinguisher ready for possible re-ignition. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

CARGO FIRE: DO NOT fight fire when fire reaches cargo! Cargo may EXPLODE! Stop all traffic and clear the area for at least 1600 meters (1 mile) in all directions and let burn. Do not move cargo or vehicle if cargo has been exposed to heat.

TIRE OR VEHICLE FIRE: Use plenty of water - FLOOD it! If water is not available, use CO2, dry chemical or dirt. If possible, and WITHOUT RISK, use unmanned master stream devices or monitor nozzles from maximum distance to prevent fire from spreading to cargo area. Pay special attention to tire fires as re-ignition may occur. Stand by, at a safe distance, with extinguisher ready for possible re-ignition. (ERG, 2024)

8.4.1 Fire Fighting Procedures

If material on fire or involved in fire: Dangerously explosive, flood with water, and apply water from as far a distance as possible.
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
If material on fire or involved in fire: Dangerously explosive, flood with water, cool all affected containers with flooding quantities of water, and apply water from as far a distance as possible. /Zirconium Picramate, wetted/
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956

8.5 Accidental Release Measures

Public Safety: ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

Spill or Leak: ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch or walk through spilled material.

Small Spill

· Flush area with large amounts of water.

Large Spill

· Wet down with water and dike for later disposal.

· KEEP "WETTED" PRODUCT WET BY SLOWLY ADDING FLOODING QUANTITIES OF WATER.

8.5.1 Isolation and Evacuation

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area immediately for at least 500 meters (1/3 mile) in all directions.

LARGE SPILL: Consider initial evacuation for 800 meters (1/2 mile) in all directions.

FIRE: If rail car or trailer is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area immediately for at least 100 meters (330 feet) in all directions.

LARGE SPILL: Consider initial evacuation for 500 meters (1/3 mile) in all directions.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Evacuation: ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

Immediate precautionary measure

· Isolate spill or leak area immediately for at least 100 meters (330 feet) in all directions.

Large Spill

· Consider initial evacuation for 500 meters (1/3 mile) in all directions.

Fire

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

8.5.2 Cleanup Methods

1. Ventilate area of spill. 2. Collect spilled material in the most convenient and safe manner and deposit in sealed containers for reclamation... . /Zirconium compound (as Zr)/
Mackison, F. W., R. S. Stricoff, and L. J. Partridge, Jr. (eds.). NIOSH/OSHA - Occupational Health Guidelines for Chemical Hazards. DHHS(NIOSH) Publication No. 81-123 (3 VOLS). Washington, DC: U.S. Government Printing Office, Jan. 1981.

8.5.3 Disposal Methods

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

8.5.4 Preventive Measures

... Process should be modified, isolated or enclosed, automatic or mechanical handling techniques, local exhaust ventilation and wet methods should be employed and direct contact with chem should be avoided. Processes and work places should be kept clean, ... Sanitary facilities ... provided, and workers encouraged to observe strict personal hygiene. Suitable and effective personal protective equipment (eg clothing, respiratory protective equipment and goggles) should be provided and, where necessary, be supplemented by barrier creams and industrial skin cleansers. Undertakings employing picric acid ... should have suitably equipped and staffed 1st-aid or medical center. ... Workers ... encouraged to report skin disorders ... .
International Labour Office. Encyclopedia of Occupational Health and Safety. Vols. I&II. Geneva, Switzerland: International Labour Office, 1983., p. 1705
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away.
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. ... Keep material out of water sources and sewers. ... Keep spilled material wet. ... Do not attempt to sweep up dry material. /Zirconium Picramate, wetted/
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
Personnel protection: Do not handle broken packages unless wearing appropriate personal protective equipment. ... Wash away any material which may have contacted the body with copious amounts of water or soap and water. /Zirconium Picramate, wetted/
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
Personnel protection: Avoid breathing fumes from burning material. ... Keep upwind.
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956

8.6 Handling and Storage

8.6.1 Nonfire Spill Response

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. DO NOT OPERATE RADIO TRANSMITTERS WITHIN 100 METERS (330 FEET) OF ELECTRIC DETONATORS. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material.

SMALL SPILL: Flush area with large amounts of water.

LARGE SPILL: Wet down with water and dike for later disposal. KEEP "WETTED" PRODUCT WET BY SLOWLY ADDING FLOODING QUANTITIES OF WATER. (ERG, 2024)

8.7 Exposure Control and Personal Protection

Protective Clothing: ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

Maximum Allowable Concentration (MAK)
1.0 [mg/m3], inhalable fraction (metal and insol. cmpds.)[German Research Foundation (DFG)]

8.7.1 Permissible Exposure Limit (PEL)

5.0 [mg/m3], as Zr (compounds)

8.7.2 Immediately Dangerous to Life or Health (IDLH)

25 mg Zr/m3 (NIOSH, 2024)
25.0 [mg/m3], as Zr
25 mg/cu m /Zirconium compounds (as Zr)/
NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg

8.7.3 Threshold Limit Values (TLV)

5.0 [mg/m3], as Zr
TLV-STEL
10.0 [mg/m3], as Zr
8 hr Time Weighted Avg (TWA): 5 mg/cu m; 15 min Short Term Exposure Limit (STEL): 10 mg/cu m. /Zirconium and compounds, as Zr/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH 2015, p. 61
A4; Not classifiable as a human carcinogen. /Zirconium and compounds, as Zr/
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH 2015, p. 61

8.7.4 Emergency Response Planning Guidelines

Emergency Response: ERG 2024, Guide 113 (Zirconium picramate, wetted with not less than 20% water)

CARGO Fire

· DO NOT fight fire when fire reaches cargo! Cargo may EXPLODE!

· Stop all traffic and clear the area for at least 1600 meters (1 mile) in all directions and let burn.

· Do not move cargo or vehicle if cargo has been exposed to heat.

TIRE or VEHICLE Fire

· Use plenty of water - FLOOD it! If water is not available, use CO2, dry chemical or dirt.

· If possible, and WITHOUT RISK, use unmanned master stream devices or monitor nozzles from maximum distance to prevent fire from spreading to cargo area.

· Pay special attention to tire fires as re-ignition may occur. Stand by, at a safe distance, with extinguisher ready for possible re-ignition.

8.7.5 Other Standards Regulations and Guidelines

West Germany: 5 mg/cu m (1974); USSR: 6 mg/cu m (insol cmpd) /Zirconium, as Zr/
American Conference of Governmental Industrial Hygienists. Documentation of the Threshold Limit Values and Biological Exposure Indices. 5th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, 1986., p. 647

8.7.6 Personal Protective Equipment (PPE)

Excerpt from ERG Guide 112 [Explosives - Division 1.1, 1.2, 1.3 or 1.5]:

Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Excerpt from ERG Guide 113 [Flammable Materials (Wet / Desensitized Explosive)]:

Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Personnel protection: Wear appropriate chemical protective gloves, boots, and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. /Zirconium picramate, wetted/
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
Personnel protection: Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. /Zirconium picramate/
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. Association of American Railroads, Pueblo, CO. 2005, p. 956
Employees should be provided with and required to use impervious clothing, gloves, face shields (eight-in minimum), and other appropriate protective clothing necessary to prevent repeated or prolonged skin contact with zirconium oxide, zirconium oxychloride, zirconyl acetate, or liquids containing these compounds, and to prevent skin contact with zirconium tetrachloride or liquids containing zirconium tetrachloride, where skin contact may occur. /Zirconium compounds/
Mackison, F. W., R. S. Stricoff, and L. J. Partridge, Jr. (eds.). NIOSH/OSHA - Occupational Health Guidelines for Chemical Hazards. DHHS(NIOSH) Publication No. 81-123 (3 VOLS). Washington, DC: U.S. Government Printing Office, Jan. 1981.
Respirator Recommendations: Up to 25 mg/cu m: /Zirconium compounds (as Zr)/
Assigned Protection Factor (APF)
APF = 5
Respirator Recommendations
Any quarter-mask respirator.
NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg
For more Personal Protective Equipment (PPE) (Complete) data for ZIRCONIUM PICRAMATE (7 total), please visit the HSDB record page.

8.8 Stability and Reactivity

8.8.1 Air and Water Reactions

No rapid reaction with air. No rapid reaction with water.

8.8.2 Reactive Group

Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Amines, Aromatic

Phenolic Salts

Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Amines, Aromatic

Phenolic Salts

Water and Aqueous Solutions

8.8.3 Reactivity Alerts

Explosive

Strong Oxidizing Agent

Strong Oxidizing Agent

8.8.4 Reactivity Profile

Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; Treat as an explosive. Keep material wet with water or treat as an explosive
ZIRCONIUM PICRAMATE, WETTED WITH NOT LESS THAN 20% WATER is an oxidizing agent. May react vigorously with reducing materials. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock. Treat as an explosive.

8.8.5 Hazardous Reactivities and Incompatibilities

... Can react vigorously with oxidizing materials.
Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 2703

8.9 Transport Information

8.9.1 DOT Emergency Guidelines

/GUIDE 113 FLAMMABLE SOLIDS - TOXIC (Wet/Desensitized Explosive)/ Fire or Explosion: Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; Treat as an explosive (GUIDE 112). Keep material wet with water or treat as an explosive (GUIDE 112). Runoff to sewer may create fire or explosion hazard. /Zirconium picramate, wetted with not less than 20% water/
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 113 FLAMMABLE SOLIDS - TOXIC (Wet/Desensitized Explosive)/ Health: Some are toxic and may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution. /Zirconium picramate, wetted with not less than 20% water/
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 113 FLAMMABLE SOLIDS - TOXIC (Wet/Desensitized Explosive)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. Isolate spill or leak area immediately for at least 100 meters (330 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Ventilate closed spaces before entering. /Zirconium picramate, wetted with not less than 20% water/
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
/GUIDE 113 FLAMMABLE SOLIDS - TOXIC (Wet/Desensitized Explosive)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. /Zirconium picramate, wetted with not less than 20% water/
U.S. Department of Transportation. 2012 Emergency Response Guidebook. Washington, D.C. 2012
For more DOT Emergency Guidelines (Complete) data for ZIRCONIUM PICRAMATE (8 total), please visit the HSDB record page.

8.9.2 Shipping Name / Number DOT/UN/NA/IMO

UN 1517; Zirconium picramate, wetted with not less than 20% water, by mass
UN 0236; Zirconium picramate, dry or wetted with less than 20% water, by mass
IMO 4.1; Zirconium picramate, wetted with not less 20% water, by mass
IMO 1.3C; Zirconium picramate, dry or wetted with less than 20% water, by mass

8.9.3 Standard Transportation Number

49 171 95; Zirconium picramate, wet (with at least 20% of water)

8.9.4 Shipment Methods and Regulations

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
49 CFR 171.2 (USDOT); U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of April 10, 2015: https://www.ecfr.gov
The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.
International Air Transport Association. Dangerous Goods Regulations. 55th Edition. Montreal, Quebec Canada. 2014., p. 326
The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
International Maritime Organization. IMDG Code. International Maritime Dangerous Goods Code Volume 2 2012, p. 32, 74

8.9.5 DOT Label

Explosive 1.3C
Flammable Solid

9 Toxicity

9.1 Toxicological Information

9.1.1 Toxicity Summary

IDENTIFICATION AND USE: No data. HUMAN EXPOSURE AND TOXICITY: At time of review no toxicity data for Zirconium picramate was found. ANIMAL STUDIES: No data.

9.1.2 Adverse Effects

Dermatotoxin - Skin burns.

Skin Sensitizer - An agent that can induce an allergic reaction in the skin.

9.1.3 Antidote and Emergency Treatment

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/
Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3rd revised edition, Elsevier Mosby, St. Louis, MO 2007, p. 160
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/
Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3rd revised edition, Elsevier Mosby, St. Louis, MO 2007, p. 160
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/
Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3rd revised edition, Elsevier Mosby, St. Louis, MO 2007, p. 160-1

10 Associated Disorders and Diseases

Associated Occupational Diseases with Exposure to the Compound
Contact dermatitis, allergic [Category: Skin Disease]

11 Literature

11.1 Consolidated References

11.2 Chemical Co-Occurrences in Literature

12 Classification

12.1 ChemIDplus

12.2 CAMEO Chemicals

12.3 UN GHS Classification

12.4 EPA DSSTox Classification

12.5 EPA Substance Registry Services Tree

12.6 MolGenie Organic Chemistry Ontology

13 Information Sources

  1. CAMEO Chemicals
    LICENSE
    CAMEO Chemicals and all other CAMEO products are available at no charge to those organizations and individuals (recipients) responsible for the safe handling of chemicals. However, some of the chemical data itself is subject to the copyright restrictions of the companies or organizations that provided the data.
    https://cameochemicals.noaa.gov/help/reference/terms_and_conditions.htm?d_f=false
    ZIRCONIUM PICRAMATE, WETTED WITH NOT LESS THAN 20% WATER
    https://cameochemicals.noaa.gov/chemical/4835
    CAMEO Chemical Reactivity Classification
    https://cameochemicals.noaa.gov/browse/react
  2. CAS Common Chemistry
    LICENSE
    The data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.
    https://creativecommons.org/licenses/by-nc/4.0/
    Zirconium, tetrakis(2-amino-4,6-dinitrophenolato)-
    https://commonchemistry.cas.org/detail?cas_rn=63868-82-6
  3. ChemIDplus
    ChemIDplus Chemical Information Classification
    https://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
  4. EPA DSSTox
    Zirconium(4+) tetrakis(2-amino-4,6-dinitrophenolate)
    https://comptox.epa.gov/dashboard/DTXSID50980601
    CompTox Chemicals Dashboard Chemical Lists
    https://comptox.epa.gov/dashboard/chemical-lists/
  5. FDA Global Substance Registration System (GSRS)
    LICENSE
    Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.
    https://www.fda.gov/about-fda/about-website/website-policies#linking
  6. Hazardous Substances Data Bank (HSDB)
  7. Emergency Response Guidebook (ERG)
  8. Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
    LICENSE
    Copyright (c) 2022 Haz-Map(R). All rights reserved. Unless otherwise indicated, all materials from Haz-Map are copyrighted by Haz-Map(R). No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.
    https://haz-map.com/About
  9. Japan Chemical Substance Dictionary (Nikkaji)
  10. NITE-CMC
    Zirconium picramate - FY2007 (Dangerous substance)
    https://www.chem-info.nite.go.jp/chem/english/ghs/07-mhlw-0021e.html
  11. Wikidata
    Zirconium(4+) tetrakis(2-amino-4,6-dinitrophenolate)
    https://www.wikidata.org/wiki/Q82966580
  12. PubChem
  13. GHS Classification (UNECE)
  14. EPA Substance Registry Services
  15. MolGenie
    MolGenie Organic Chemistry Ontology
    https://github.com/MolGenie/ontology/
CONTENTS