Peptide boronic acid inhibitors of trypsin-like proteases
Patent
US-5242904-A
Inventor
KETTNER CHARLES A (US)
SHENVI ASHOKKUMAR B (US)
Assignee
DU PONT MERCK PHARMA (US)
Country
United States
Dates
- Priority:1987/06/05
- Grant:1993/09/07
Description
This web page summarizes information in PubChem about patent US-5242904-A. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.
Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
1987/06/05
1992/03/09
1993/09/07
1993/09/07
KETTNER CHARLES A (US)
SHENVI ASHOKKUMAR B (US)
DU PONT MERCK PHARMA (US)
United States
C07F5/02 (inventive)
C07K5/00 (inventive)
C07F5/025 (inventive, first)
C07K5/00 (inventive)
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