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Method for separating and purifying mussel adhesive protein

Patent
US-2020062809-A1
Inventor

LEE SANG JAE (KR)

HONG BONG JIN (KR)

Assignee
KOLLODIS BIOSCIENCES INC (US)
Country
United States
Dates
  • Priority:
    2017/03/20
Description
This web page summarizes information in PubChem about patent US-2020062809-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

Provided is a method for separating and purifying a mussel adhesive protein, including the steps of: (1) crushing cells containing a mussel adhesive protein; (2) centrifuging the crushed cells to obtain an insoluble protein aggregate including the mussel adhesive protein; (3) treating the insoluble protein aggregate with an acidic organic solvent to obtain a low-purity mussel adhesive protein solution; (4) selectively precipitating the mussel adhesive protein by controlling the acidity of the low-purity mussel adhesive protein solution; and (5) treating the precipitate with a surfactant to remove endotoxins from the mussel adhesive protein. The method of the subject matter can purify a large amount of mussel adhesive proteins of high purity with a simple process. In particular, the subject matter can be applied effectively to the development of novel uses of mussel adhesive proteins by significantly reducing production costs through economical production of the mussel adhesive protein.

2 Full Text

3 Important Dates

3.1 Priority Date

2017/03/20

3.2 Filing Date

2017/03/20

3.3 Publication Date

2020/02/27

4 Inventor

LEE SANG JAE (KR)

HONG BONG JIN (KR)

5 Assignee

KOLLODIS BIOSCIENCES INC (US)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Patent Family

9 Classification

9.1 IPC

C07K1/36 (inventive)

C07K1/30 (inventive)

C07K7/08 (inventive)

C07K14/435 (inventive, first)

9.2 CPC

C07K14/435 (inventive, first)

C07K7/08 (inventive)

C07K1/36 (inventive)

C07K1/30 (inventive)

C07K14/43509 (inventive, first)

C07K1/14 (inventive, first)

C07K14/43504 (inventive)

C07K2319/00

10 Citations

11 Cited By

12 Similar Patents

13 Information Sources

  1. Google Patents
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    https://creativecommons.org/licenses/by/4.0/legalcode
  2. PubChem
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