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Epithelial-mesenchymal transition in circulating tumor cells (ctcs) negatives for cytokeratin (ck) expression in patients with non-metastatic breast cancer

Patent
US-2016273047-A1
Inventor

GARCÍA PUCHE JOSÉ LUIS (ES)

SERRANO FERNÁNDEZ MARÍA JOSÉ (ES)

LORENTE ACOSTA JOSÉ ANTONIO (ES)

MARCHAL CORRALES JUAN ANTONIO (ES)

ORTEGA SÁNCHEZ FRANCISCO GABRIEL (ES)

Assignee

SERVICIO ANDALUZ ED SALUD (ES)

UNIV GRANADA (ES)

Country
United States
Dates
  • Priority:
    2013/10/30
Description
This web page summarizes information in PubChem about patent US-2016273047-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The inventors of the present invention have surprisingly discovered that EGFR expression in nonmetastatic breast cancer patients with CK-negative CTCs could induce EMT process. A simultaneous detection of both EGFR and EMT markers (VIM and Slug) in CTCs might improve prognostic or predictive information in patients with operable breast cancer.

2 Full Text

3 Important Dates

3.1 Priority Date

2013/10/30

3.2 Filing Date

2014/10/30

3.3 Publication Date

2016/09/22

4 Inventor

GARCÍA PUCHE JOSÉ LUIS (ES)

SERRANO FERNÁNDEZ MARÍA JOSÉ (ES)

LORENTE ACOSTA JOSÉ ANTONIO (ES)

MARCHAL CORRALES JUAN ANTONIO (ES)

ORTEGA SÁNCHEZ FRANCISCO GABRIEL (ES)

5 Assignee

SERVICIO ANDALUZ ED SALUD (ES)

UNIV GRANADA (ES)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Patent Family

11 Classification

11.1 IPC

C12Q1/68 (inventive, first)

11.2 CPC

C12Q2600/158

C12Q2600/118

C12Q2600/106

C12Q1/6886 (inventive, first)

12 Citations

  • WO-0035473-A2 (PRS)
  • Gusterson ( Breast cancer research (2005) volume7, pages 143-148) (PRS)
  • Iseri (Biomedicine & Pharmacotherapy (2011) volume 65, pages 40-45) (PRS)
  • Wang (Cancer Research (2011) volume 71, pages 1526-1532) (PRS)

13 Cited By

14 Similar Patents

15 Information Sources

  1. Google Patents
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  2. PubChem
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