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Dpyd gene variants and use thereof

Patent
US-2011311972-A1
Inventor

WAGNER SUSANNE (US)

JENNIFER POTTER (US)

Assignee

WAGNER SUSANNE (US)

JENNIFER POTTER (US)

MYRIAD GENETICS INC (US)

Country
United States
Dates
  • Priority:
    2006/06/23
Description
This web page summarizes information in PubChem about patent US-2011311972-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme.

2 Full Text

3 Important Dates

3.1 Priority Date

2006/06/23

3.2 Filing Date

2011/05/10

3.3 Publication Date

2011/12/22

4 Inventor

WAGNER SUSANNE (US)

JENNIFER POTTER (US)

5 Assignee

WAGNER SUSANNE (US)

JENNIFER POTTER (US)

MYRIAD GENETICS INC (US)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Linked Taxonomies

11 Patent Family

12 Classification

12.1 IPC

C12Q1/68 (inventive, first)

12.2 CPC

C12Q2600/158

C12Q1/6883 (inventive, first)

C12Q2600/156

C12N9/001 (inventive)

C12Q2600/172

13 Citations

  • Kleiblova (Puvodni Prace (February 2007) pages 215-219) (PRS)
  • NCBI ss300 (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ss.cgi?subsnp_id=300, entered 11/24/1998) (PRS)
  • ss48295484 (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ss.cgi?subsnp_id=48295484; entered Aug 19, 2005). (PRS)
  • The international SNP MAP working group (Nature (2001) volume 409, pages 928-933) (PRS)

14 Cited By

15 Similar Patents

16 Information Sources

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  2. PubChem
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