Dpyd gene variants and use thereof
Patent
US-2011311972-A1
Inventor
WAGNER SUSANNE (US)
JENNIFER POTTER (US)
Assignee
WAGNER SUSANNE (US)
JENNIFER POTTER (US)
MYRIAD GENETICS INC (US)
Country
United States
Dates
- Priority:2006/06/23
Description
This web page summarizes information in PubChem about patent US-2011311972-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.
Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme.
2006/06/23
2011/05/10
2011/12/22
WAGNER SUSANNE (US)
JENNIFER POTTER (US)
WAGNER SUSANNE (US)
JENNIFER POTTER (US)
MYRIAD GENETICS INC (US)
United States
C12Q1/68 (inventive, first)
C12Q2600/158
C12Q1/6883 (inventive, first)
C12Q2600/156
C12N9/001 (inventive)
C12Q2600/172
- Kleiblova (Puvodni Prace (February 2007) pages 215-219) (PRS)
- NCBI ss300 (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ss.cgi?subsnp_id=300, entered 11/24/1998) (PRS)
- ss48295484 (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ss.cgi?subsnp_id=48295484; entered Aug 19, 2005). (PRS)
- The international SNP MAP working group (Nature (2001) volume 409, pages 928-933) (PRS)
RU-2701375-C1 (SEA)
- Google PatentsLICENSE"Google Patents Research Data" by Google, based on data provided by IFI CLAIMS Patent Services and OntoChem, is licensed under a Creative Commons Attribution 4.0 International License.https://creativecommons.org/licenses/by/4.0/legalcode
- PubChem
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