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2-arylbenzimidazoles as Ppargc1a activators for treating neurodegenerative diseases

Patent
US-11111217-B2
Inventor

BANISTER SAMUEL D (AU)

ENGLEMAN EDGAR (US)

NGUYEN KHOA D (US)

SMITH MARK (US)

Assignee
UNIV LELAND STANFORD JUNIOR (US)
Country
United States
Dates
  • Priority:
    2018/08/06
  • Grant:
    2021/09/07
Description
This web page summarizes information in PubChem about patent US-11111217-B2. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The compound 2-(4-tert-Butylphenyl)-1H-benzo[d]imidazol-5-ol: n nand its use are disclosed. The compound activates Ppargc1a and, as a consequence, is useful for treating neuroinflammation and for treating a variety of neurodegenerative diseases.

2 Full Text

3 Important Dates

3.1 Priority Date

2018/08/06

3.2 Filing Date

2020/10/13

3.3 Publication Date

2021/09/07

3.4 Grant Date

2021/09/07

4 Inventor

BANISTER SAMUEL D (AU)

ENGLEMAN EDGAR (US)

NGUYEN KHOA D (US)

SMITH MARK (US)

5 Assignee

UNIV LELAND STANFORD JUNIOR (US)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Patent Family

11 Classification

11.1 IPC

A61K31/4184 (inventive, first)

C07D235/08 (inventive)

11.2 CPC

C07F9/65068 (inventive)

C07D277/66 (inventive)

C07D235/08 (inventive)

C07B2200/05

C07D487/04 (inventive)

C07D263/57 (inventive)

C07D235/18 (inventive, first)

A61P25/28 (inventive)

A61P25/00 (inventive, first)

A61K31/437 (inventive)

A61K31/4184 (inventive)

C07D417/04 (inventive)

C07D471/04 (inventive)

C07D401/04 (inventive)

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