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Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds

Patent
US-10487093-B2
Inventor

COOPER IAN (GB)

LYONS AMANDA (GB)

ORR DAVID (GB)

KIRKHAM JAMES (GB)

BLADES KEVIN (GB)

Assignee
REDX PHARMA PLC (GB)
Country
United States
Dates
  • Priority:
    2016/02/08
  • Grant:
    2019/11/26
Description
This web page summarizes information in PubChem about patent US-10487093-B2. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.

2 Full Text

3 Important Dates

3.1 Priority Date

2016/02/08

3.2 Filing Date

2017/02/08

3.3 Publication Date

2019/11/26

3.4 Grant Date

2019/11/26

4 Inventor

COOPER IAN (GB)

LYONS AMANDA (GB)

ORR DAVID (GB)

KIRKHAM JAMES (GB)

BLADES KEVIN (GB)

5 Assignee

REDX PHARMA PLC (GB)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Taxonomies

9 Patent Family

10 Classification

10.1 IPC

A61K31/428 (inventive)

A61K31/5415 (inventive)

A61K31/423 (inventive, first)

A61P31/04 (inventive)

A61K31/536 (inventive)

C07D263/58 (inventive)

C07D519/00 (inventive)

C07D498/04 (inventive)

A61K31/5383 (inventive)

10.2 CPC

C07D519/00 (inventive, first)

A61P31/04 (inventive)

A61K31/423 (inventive)

C07D498/04 (inventive)

C07D263/58 (inventive, first)

A61P31/06 (inventive)

A61K31/5383 (inventive)

Y02A50/30

11 Citations

  • US-2007037781-A1 (SEA)
  • WO-2008126024-A2 (APP)
  • WO-2008126034-A2 (APP)
  • WO-2009104159-A1 (APP)
  • WO-2013021363-A1 (APP)
  • WO-2013068948-A1 (APP)
  • WO-2013080156-A1 (APP)
  • Hameed et al., "Novel N-Linked Aminipiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy Against Mycobacterium Tuberculosis," Journal of Medicinal Chemistry, 57(11):4889-4905 (2014). (APP)
  • International Search Report and Written Opinion for International Application No. PCT/GB2017/050318 dated May 9, 2017. (APP,APP)
  • Reck et al., "Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity," Journal of Medicinal Chemistry, 54(22):7834-7847 (2011). (APP)

12 Similar Patents

13 Information Sources

  1. Google Patents
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