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Tamper-resistant dosage form with immediate release and resistance against solvent extraction

Patent
EP-3698776-A1
Inventor

IMMOHR ISABELL (DE)

WENING KLAUS (DE)

Assignee
GRUENENTHAL GMBH (DE)
Country
European Patent Office
Dates
  • Priority:
    2019/02/19
Description
This web page summarizes information in PubChem about patent EP-3698776-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The invention relates to a tamper-resistant pharmaceutical dosage form comprising a multitude of particles which comprise a pharmacologically active compound, preferably selected from opioids; a polyalkylene oxide having a weight average molecular weight within the range of from 200,000 g/mol to 2,000,000 g/mol, and a disintegrant; wherein the pharmacologically active compound is dispersed in a matrix comprising the polyalkylene oxide and the disintegrant; wherein the content of the disintegrant is more than 20 wt.-%, based on the total weight of the particles; wherein the content of the polyalkylene oxide is at least 25 wt.-%, based on the total weight of the particles; and wherein the dosage form provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.

2 Full Text

3 Important Dates

3.1 Priority Date

2019/02/19

3.2 Filing Date

2019/02/19

3.3 Publication Date

2020/08/26

4 Inventor

IMMOHR ISABELL (DE)

WENING KLAUS (DE)

5 Assignee

GRUENENTHAL GMBH (DE)

6 Country

European Patent Office

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Taxonomies

9 Classification

9.1 IPC

A61K9/14 (inventive, first)

A61K31/00 (inventive)

A61K9/20 (inventive)

9.2 CPC

A61K9/146 (inventive, first)

A61K9/1641

A61K9/2031 (inventive)

A61K31/485 (inventive)

10 Citations

11 Similar Patents

12 Information Sources

  1. Google Patents
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  2. PubChem
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