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Fh-binding protein of streptococcus pneumoniae

Patent
EP-1301602-A2
Inventor

BJORCK LARS (SE)

SJOHOLM ANDERS (SE)

JANULCZYK ROBERT (SE)

POZZI GIANNI (IT)

IANNELLI FRANCESCO (IT)

Assignee
HANSA MEDICAL AB (SE)
Country
European Patent Office
Dates
  • Priority:
    2000/07/20
Description
This web page summarizes information in PubChem about patent EP-1301602-A2. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The present invention provides proteins and peptides derived from Streptococcus pneumoniae, type 3, which bind the complement factor H (fH). These proteins and peptides show a homology of at least 50 %, preferably at least 60 %, and most preferably at least 70 % with the subsequence from Thr38 to Lys 149 of the sequence disclosed herein as SEQ ID NO:1. The above subsequence, which is located in the amino-terminal of a surface protein isolated from Streptococcus Pneumoniae, type 3, is highly associated with binding of fH. In another aspect, the invention relates to proteins and peptides showing a homology of at least 85 %, preferably at least 95 %, and most preferably at least 99 % with the Hic protein, the amino acid sequence of which is disclosed is SEQ ID NO:1. The invention also provides vaccine compositions comprising the above proteins and peptides.

2 Full Text

3 Important Dates

3.1 Priority Date

2000/07/20

3.2 Filing Date

2001/07/19

3.3 Publication Date

2003/04/16

4 Inventor

BJORCK LARS (SE)

SJOHOLM ANDERS (SE)

JANULCZYK ROBERT (SE)

POZZI GIANNI (IT)

IANNELLI FRANCESCO (IT)

5 Assignee

HANSA MEDICAL AB (SE)

6 Country

European Patent Office

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Linked Taxonomies

11 Patent Family

12 Classification

12.1 IPC

A61K31/711 (inventive)

A61K39/00 (inventive)

C07K/ (inventive)

C07K16/12 (inventive)

A61K45/00 (inventive)

C12N15/63 (inventive)

C12N15/31 (inventive)

C12N5/10 (inventive)

C12Q1/02 (inventive)

G01N33/566 (inventive)

C12N1/21 (inventive)

C12N1/19 (inventive)

C12P21/08 (inventive)

C12N1/15 (inventive)

G01N33/53 (inventive)

C07K14/315 (inventive)

A61P11/00 (inventive)

C12N15/09 (inventive)

A61K39/09 (inventive)

G01N33/15 (inventive)

A61P43/00 (inventive)

A61K38/00 (inventive)

G01N33/50 (inventive, first)

A61P31/04 (inventive)

13 Citations

  • None (EXA)
  • See also references of WO 0208426A3 (EXA)

14 Similar Patents

15 Information Sources

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  2. PubChem
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