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Inhibition of abnormal growth of synovial cells using il-6 antagonist as active ingredient

Patent
EP-0783893-B1
Inventor

KISHIMOTO TADAMITSU (JP)

MIHARA MASAHIKO (JP)

MORIYA YOICHIRO (JP)

OHSUGI YOSHIYUKI (JP)

Assignee

CHUGAI PHARMACEUTICAL CO LTD (JP)

KISHIMOTO TADAMITSU (JP)

Country
European Patent Office
Dates
  • Priority:
    1994/10/07
  • Grant:
    2012/04/04
Description
This web page summarizes information in PubChem about patent EP-0783893-B1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

There is provided a synovial cell growth inhibitor, or a pharmaceutical composition for treatment of chronic rheumatoid arthritis based on the synovial cell growth inhibitor. The pharmaceutical composition for treatment of chronic rheumatoid arthritis or synovial cell growth inhibitor contains an IL-6 antagonist, such as IL-6 antibody or IL-6R antibody, as an effective component.

2 Full Text

3 Important Dates

3.1 Priority Date

1994/10/07

3.2 Filing Date

1995/06/07

3.3 Publication Date

2012/04/04

3.4 Grant Date

2012/04/04

4 Inventor

KISHIMOTO TADAMITSU (JP)

MIHARA MASAHIKO (JP)

MORIYA YOICHIRO (JP)

OHSUGI YOSHIYUKI (JP)

5 Assignee

CHUGAI PHARMACEUTICAL CO LTD (JP)

KISHIMOTO TADAMITSU (JP)

6 Country

European Patent Office

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Linked Taxonomies

11 Patent Family

12 Classification

12.1 IPC

A61K38/20 (inventive)

A61K39/395 (inventive, first)

C12N15/02 (inventive, first)

A61P37/00 (inventive)

C07K16/24 (inventive)

C12R1/91

A61P43/00 (inventive)

C12P21/08 (inventive)

A61P29/00 (inventive)

C07K16/28 (inventive)

A61K38/00

12.2 CPC

A61P43/00 (inventive)

A61P37/00 (inventive)

A61P29/00 (inventive)

A61P19/02 (inventive)

A61P19/04 (inventive)

C07K16/244 (inventive, first)

C07K16/248 (inventive)

C07K16/2866 (inventive)

A61K38/00

13 Citations

  • JP-H04187646-A (EXA)
  • ATSUO MURATA ET AL: "possible implications of cytokines in the pathophysiology of acute pancreatitis", SAISHIN IGAKU, vol. 47, no. 11, 1992, pages 49 - 56 (EXA)
  • H. HEREMANS ET AL: "Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 22, 1992, pages 2395 - 2401 (EXA)
  • J. WIIDENES: "Interleukin-6 antibodies in rheumatoid arthritis", JOURNAL OF INTERFERON RESEARCH, vol. 14, 1994, pages 297 - 298 (EXA)
  • R. BELLOMO: "the cytokine network in the critically ill", ANEASTHESIA AND INTENSIVE CARE, vol. 20, no. 3, 1992, pages 288 - 302 (EXA)

14 Cited By

15 Similar Patents

16 Information Sources

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