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Amplified antibiotic and antitumor agents

Patent
EP-0055716-B1
Country
European Patent Office
Dates
  • Priority:
    1980/06/24
  • Grant:
    1984/11/07
Description
This web page summarizes information in PubChem about patent EP-0055716-B1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The antibacterial and antitumor activity of certain specific members of the groups of compounds known as phleomycin, bleomycin and tallysomycin are amplified by administration in association with caffeine, dimethylthiocyanine or pyronine Y. The invention makes the active compounds effective at very low concentrations thereby avoiding the deleterious side effects normally associated with these compounds. The active compounds according to the present invention which show particularly advantageous characteristics when amplified as described above are those in which the phleomycin, bleomycin or tallysomycin is in an amide form having a substituent amine group selected from the following:

2 Full Text

3 Important Dates

3.1 Priority Date

1980/06/24

3.2 Filing Date

1981/06/23

3.3 Publication Date

1984/11/07

3.4 Grant Date

1984/11/07

4 Country

European Patent Office

5 Linked Chemicals

5.1 PubChem Compounds

5.2 PubChem Substances

6 Linked Taxonomies

7 Patent Family

8 Classification

8.1 IPC

A61K31/35 (inventive, first)

A61K31/52 (inventive)

A61K31/70 (inventive)

C07K9/00 (inventive)

8.2 CPC

A61K31/70 (inventive, first)

C07K9/003 (inventive)

9 Citations

CHEMICAL ABSTRACTS, VOL: 82, No. 11, March 17, 1975, page 78, column 2, abstract no. 68750t, Columbus, Ohio, US, A.M. ANGYAL et al.: "Purines as amplifiers of the antibiotic activity of phleomycin against Escherichia coli B." (EXA)

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11 Information Sources

  1. Google Patents
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