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Eng - endoglin (Norway rat)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-26
Description
Enables type II transforming growth factor beta receptor binding activity. Involved in several processes, including cellular response to mechanical stimulus; extracellular matrix constituent secretion; and positive regulation of metabolic process. Located in cell surface and extracellular space. Used to study congestive heart failure; pre-eclampsia; and renal fibrosis. Biomarker of cholestasis; congestive heart failure; hepatocellular carcinoma; hypertension (multiple); and renal fibrosis. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin).

1 Names and Identifiers

1.1 Synonyms

1.1.1 MeSH Entry Terms

  • CD105 Antigen
  • Endoglin Protein

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 RGD ID

1.2.4 Wikidata

3 Interactions and Pathways

3.1 Pathways

4 Expression

5 Literature

5.1 NLM Curated PubMed Citations

5.2 Gene-Chemical Co-Occurrences in Literature

5.3 Gene-Gene Co-Occurrences in Literature

5.4 Gene-Disease Co-Occurrences in Literature

6 Patents

6.1 Gene-Chemical Co-Occurrences in Patents

6.2 Gene-Gene Co-Occurrences in Patents

6.3 Gene-Disease Co-Occurrences in Patents

7 Classification

7.1 MeSH Tree

8 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
  4. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  5. NCBI Gene Expression Omnibus (GEO)
  6. Rat Genome Database (RGD)
    LICENSE
    Creative Commons Attribution 4.0 International license (CC BY 4.0)
    https://creativecommons.org/licenses/by/4.0/
  7. Wikidata
CONTENTS