Eng - endoglin (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-26
Description
Enables type II transforming growth factor beta receptor binding activity. Involved in several processes, including cellular response to mechanical stimulus; extracellular matrix constituent secretion; and positive regulation of metabolic process. Located in cell surface and extracellular space. Used to study congestive heart failure; pre-eclampsia; and renal fibrosis. Biomarker of cholestasis; congestive heart failure; hepatocellular carcinoma; hypertension (multiple); and renal fibrosis. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin).
- CD105 Antigen
- Endoglin Protein
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- PubChem
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- NCBI Gene Expression Omnibus (GEO)
- Rat Genome Database (RGD)LICENSECreative Commons Attribution 4.0 International license (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
- Wikidata
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