Cd93 - CD93 antigen (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-02-02
Description
Predicted to enable complement component C1q complex binding activity. Predicted to be involved in cell-cell adhesion. Located in cell surface; cytoplasmic vesicle; and plasma membrane. Is expressed in blood vessel and early conceptus. Orthologous to human CD93 (CD93 molecule).
- 6030404G09Rik
- AA4.1
- C1qr1
- C1qrp
- Ly68
- complement component C1q receptor
- C1q/MBL/SPA receptor
- C1qR(p)
- cell surface antigen AA4
- complement component 1, q subcomponent, receptor 1
- ly-68
- lymphocyte antigen 68
- CD93 (human)
- CD93 (black-footed ferret)
- CD93 (European mink)
- CD93 (Ahaetulla prasina)
- CD93 (red-backed fairy wren)
- CD93 (Oenanthe melanoleuca)
- CD93 (Chinese forest musk deer)
- CD93 (raccoon dog)
- CD93 (Leopard gecko)
- CD93 (Pteronotus mesoamericanus)
- CD93 (black-legged kittiwake)
- CD93 (Aeolian wall lizard)
- CD93 (graceful crag lizard)
- CD93 (takin)
- CD93 (yellow-footed antechinus)
- CD93 (California condor)
- CD93 (Macaca thibetana thibetana)
- CD93 (Northern goshawk)
- CD93 (snow leopard)
- CD93 (Loggerhead turtle)
- CD93 (Sphaerodactylus townsendi)
- CD93 (Eurasian river otter)
- CD93 (bobcat)
- CD93 (greater spear-nosed bat)
- CD93 (American black bear)
- CD93 (Ring-tailed lemur)
- CD93 (Agile Gracile Mouse Opossum)
- CD93 (American mink)
- CD93 (leopard cat)
- CD93 (elk)
- CD93 (fence lizard)
- CD93 (Arctic fox)
- CD93 (rufous-necked snowfinch)
- CD93 (white-rumped snowfinch)
- CD93 (jaguarundi)
- CD93 (common toad)
- CD93 (common frog)
- CD93 (scimitar-horned oryx)
- CD93 (Barn swallow)
- CD93 (Indian flying fox)
- CD93 (Eurasian tree sparrow)
- CD93 (Corvus cornix cornix)
- CD93 (Reeves's turtle)
- CD93 (Tiger rattlesnake)
- CD93 (striped hyena)
- CD93 (leatherback sea turtle)
- CD93 (Iberian mole)
- CD93 (Jamaican fruit-eating bat)
- CD93 (Sturnira hondurensis)
- CD93 (Kuhl's pipistrelle)
- CD93 (Myotis myotis)
- CD93 (Pallas's mastiff bat)
- CD93 (black swan)
- CD93 (common lizard)
- CD93 (Southern elephant seal)
- CD93 (Trachemys scripta elegans)
- CD93 (Pantherophis guttatus)
- CD93 (Gabon caecilian)
- CD93 (Francois's langur)
- CD93 (greater horseshoe bat)
- CD93 (common barn owl)
- CD93 (sea lamprey)
- CD93 (Abingdon island giant tortoise)
- CD93 (vaquita)
- CD93 (tufted duck)
- CD93 (silvery gibbon)
- CD93 (Tasmanian devil)
- CD93 (ring-necked pheasant)
- CD93 (Kakapo)
- CD93 (Microcaecilia unicolor)
- CD93 (Aquila chrysaetos chrysaetos)
- CD93 (Common wall lizard)
- CD93 (pale spear-nosed bat)
- CD93 (Steller sea lion)
- CD93 (willow flycatcher)
- CD93 (Green sea turtle)
- CD93 (Saker falcon)
- CD93 (California sea lion)
- CD93 (eastern brown snake)
- CD93 (mainland tiger snake)
- CD93 (brown bear)
- CD93 (Nothoprocta perdicaria)
- CD93 (red fox)
- CD93 (puma)
- CD93 (dingo)
- CD93 (gelada)
- CD93 (Yangtze finless porpoise)
- CD93 (common vampire bat)
- CD93 (Ugandan red Colobus)
- CD93 (beluga whale)
- CD93 (Hawaiian monk seal)
- CD93 (white-rumped munia)
- CD93 (helmeted guineafowl)
- CD93 (koala)
- CD93 (central bearded dragon)
- CD93 (zebu cattle)
- CD93 (great roundleaf bat)
- CD93 (Australian saltwater crocodile)
- CD93 (Gharial)
- CD93 (leopard)
- CD93 (western lowland gorilla)
- CD93 (black snub-nosed monkey)
- CD93 (Malayan pangolin)
- CD93 (Panamanian white-faced capuchin)
- CD93 (Miniopterus natalensis)
- CD93 (Egyptian rousette)
- CD93 (Japanese quail)
- CD93 (Taiwan habu)
- CD93 (Great Tit)
- CD93 (Gekko japonicus)
- CD93 (cheetah)
- CD93 (Common starling)
- CD93 (ass)
- CD93 (rock pigeon)
- CD93 (Swan goose)
- CD93 (gray mouse lemur)
- CD93 (Coquerel's sifaka)
- CD93 (sooty mangabey)
- CD93 (drill)
- CD93 (Colobus angolensis palliatus)
- CD93 (pig-tailed macaque)
- CD93 (large flying fox)
- CD93 (Arabian camel)
- CD93 (Bactrian camel)
- CD93 (Bison bison bison)
- CD93 (turkey)
- CD93 (bald eagle)
- CD93 (golden snub-nosed monkey)
- CD93 (cuckoo roller)
- CD93 (Downy woodpecker)
- CD93 (killdeer)
- CD93 (common cuckoo)
- CD93 (Common canary)
- CD93 (polar bear)
- CD93 (American crow)
- CD93 (Sunda flying lemur)
- CD93 (Przewalski's horse)
- CD93 (big brown bat)
- CD93 (Philippine tarsier)
- CD93 (green monkey)
- CD93 (Yangtze River dolphin)
- CD93 (minke whale)
- CD93 (sperm whale)
- CD93 (tiger)
- CD93 (black flying fox)
- CD93 (Myotis davidii)
- CD93 (Weddell seal)
- CD93 (American alligator)
- CD93 (alpaca)
- CD93 (Wild Bactrian camel)
- CD93 (Chinese tree shrew)
- CD93 (little brown bat)
- CD93 (water buffalo)
- CD93 (wild yak)
- CD93 (Brandt's bat)
- CD93 (goat)
- CD93 (crab-eating macaque)
- CD93 (Tibetan ground-tit)
- Cd93 (long-tailed chinchilla)
- CD93 (western painted turtle)
- CD93 (domestic ferret)
- CD93 (small Madagascar hedgehog)
- CD93 (European shrew)
- CD93 (American pika)
- CD93 (nine-banded armadillo)
- CD93 (Pacific walrus)
- CD93 (killer whale)
- CD93 (domestic cat)
- CD93 (Bolivian squirrel monkey)
- CD93 (olive baboon)
- CD93 (pygmy chimpanzee)
- CD93 (small-eared galago)
- CD93 (African savanna elephant)
- CD93 (northern white-cheeked gibbon)
- CD93 (giant panda)
- CD93 (Sumatran orangutan)
- CD93 (white-tufted-ear marmoset)
- CD93 (rabbit)
- CD93 (sheep)
- CD93 (zebra finch)
- CD93 (pig)
- cd93 (tropical clawed frog)
- CD93 (platypus)
- CD93 (horse)
- CD93 (gray short-tailed opossum)
- CD93 (Rhesus monkey)
- CD93 (dog)
- CD93 (domestic cattle)
- CD93 (chimpanzee)
- CD93 (chicken)
- Cd93 (Norway rat)
Cell surface receptor that plays a role in various physiological processes including inflammation, phagocytosis, and cell adhesion (PMID: 15004139, PMID: 20439917, PMID: 38441970). Plays a role in phagocytosis and enhances the uptake of apoptotic cells and immune complexes by acting as a receptor for defense collagens including surfactant protein A/SFTPA1, C1q, and mannose-binding lectin (MBL2) (PMID: 15004139). Plays a role in the regulation of endothelial cell function and adhesion by activating angiogenesis. Mechanistically, exerts its angiogenic function by associating with beta-dystroglycan, leading to SRC-dependent phosphorylation and subsequent recruitment of CBL. In turn, CBL provides a docking site for downstream signaling components, such as CRKL to enhance cell migration. Participates in angiogenesis also by acting as a receptor for the ECM pan-endothelial glycoprotein multimerin-2/MMRN2 and IGFBP7 ligands. Both ligands play a non-redundant role in CD93-mediated endothelial cell function (By similarity). Acts as a key regulator of endothelial barrier function through modulating VEGFR2 function (PMID: 38441970).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- NCBI Gene Expression Omnibus (GEO)
- STRING: functional protein association networks
- Swiss Institute of Bioinformatics Bgee
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