Bethanechol
- bethanechol
- 674-38-4
- Amidopropyldimethylbetaine
- Carbamyl-beta-methylcholine
- Carbamoyl-beta-methylcholine
- Create:2005-03-25
- Modify:2025-01-11
- Bethanechol
- Bethanechol Chloride
- Bethanecol
- Chloride, Bethanechol
- Duvoid
- Hermes, Myo
- Myo Hermes
- Myocholine
- Myotonachol
- Myotonine
- PMS Bethanechol Chloride
- PMS-Bethanechol Chloride
- Urecholine
- Urocarb
- bethanechol
- 674-38-4
- Amidopropyldimethylbetaine
- Carbamyl-beta-methylcholine
- Carbamoyl-beta-methylcholine
- (2-Hydroxypropyl)trimethylammonium carbamate
- 2-carbamoyloxypropyl-trimethylazanium
- 2-carbamoyloxypropyl(trimethyl)azanium
- BRN 1773706
- CHEBI:3084
- UNII-004F72P8F4
- 2-((Aminocarbonyl)oxy)-N,N,N-trimethyl-1-propanaminium
- Ammonium, (2-hydroxypropyl)trimethyl-, carbamate (ester)
- 2-carbamoyloxypropyl-trimethyl-azanium
- 004F72P8F4
- 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium
- 1-Propanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-
- Bethanecol
- 1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, (S)-
- NCGC00163217-01
- 2-carbamoyloxypropyl(trimethyl)azanium;chloride
- Carbamyl--methylcholine
- Spectrum_000084
- Prestwick0_001073
- Prestwick1_001073
- Prestwick2_001073
- Prestwick3_001073
- Spectrum2_000132
- Spectrum3_000311
- Spectrum4_000255
- Spectrum5_000892
- BETHANECHOL [VANDF]
- CHEMBL1482
- Lopac0_000304
- SCHEMBL37096
- BETHANECHOL [WHO-DD]
- BSPBio_001086
- BSPBio_001902
- GTPL297
- KBioGR_000690
- KBioSS_000504
- cid_11548
- DivK1c_000179
- SPBio_000204
- SPBio_002993
- BPBio1_001196
- DTXSID5048398
- BDBM39342
- KBio1_000179
- KBio2_000504
- KBio2_003072
- KBio2_005640
- KBio3_001402
- NINDS_000179
- HMS2089I08
- HY-B0406
- AKOS025310166
- CCG-204399
- CS-4994
- DB01019
- IDI1_000179
- NCGC00015245-03
- NCGC00015245-04
- NCGC00015245-06
- NCGC00015245-07
- NCGC00015245-08
- NCGC00015245-18
- NCGC00089770-02
- DA-71442
- SY112089
- SBI-0050292.P004
- AB00053794
- NS00007014
- 2-carbamoyloxypropyl(trimethyl)ammonium;chloride
- C06850
- AB00053794-14
- AB00053794-15
- AB00053794_16
- AB00053794_17
- 2-aminocarbonyloxypropyl(trimethyl)azanium;chloride
- Q419059
- BRD-A99833829-003-25-5
- BRD-A99833829-003-26-3
- BRD-A99833829-003-27-1
Use (kg; approx.) in Germany (2009): >100
Consumption (g per capita; approx.) in Germany (2009): 0.00122
Calculated removal (%): 75.1
M Chen, V Vijay, Q Shi, Z Liu, H Fang, W Tong. FDA-Approved Drug Labeling for the Study of Drug-Induced Liver Injury, Drug Discovery Today, 16(15-16):697-703, 2011. PMID:21624500 DOI:10.1016/j.drudis.2011.05.007
M Chen, A Suzuki, S Thakkar, K Yu, C Hu, W Tong. DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug Discov Today 2016, 21(4): 648-653. PMID:26948801 DOI:10.1016/j.drudis.2016.02.015
◉ Summary of Use during Lactation
No information is available on the use of bethanechol during breastfeeding. If it is used during breastfeeding, monitor the infant for signs of cholinergic excess (diarrhea, lacrimation, and excessive salivation or urination), especially in younger, exclusively breastfed infants.
◉ Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk
Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release, and have variable effects on serum prolactin. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=NZUPCNDJBJXXRF-UHFFFAOYSA-O
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- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_useBethanecholhttps://www.drugbank.ca/drugs/DB01019
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- CCSbaseCCSbase Classificationhttps://ccsbase.net/
- ChEBI
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- Drug Gene Interaction database (DGIdb)LICENSEThe data used in DGIdb is all open access and where possible made available as raw data dumps in the downloads section.http://www.dgidb.org/downloadsBETHANECHOLhttps://www.dgidb.org/drugs/rxcui:19257[PHE13,TYR19]MCHhttps://www.dgidb.org/drugs/iuphar.ligand:1297SERIBANTUMABhttps://www.dgidb.org/drugs/iuphar.ligand:8297
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- Therapeutic Target Database (TTD)
- Drug Induced Liver Injury Rank (DILIrank) DatasetLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- Drugs and Lactation Database (LactMed)
- Japan Chemical Substance Dictionary (Nikkaji)
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.htmlAnatomical Therapeutic Chemical (ATC) classificationhttp://www.genome.jp/kegg-bin/get_htext?br08303.kegRisk category of Japanese OTC drugshttp://www.genome.jp/kegg-bin/get_htext?br08312.keg
- Metabolomics Workbench
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- NLM RxNorm TerminologyLICENSEThe RxNorm Terminology is created by the National Library of Medicine (NLM) and is in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from NLM. Credit to the U.S. National Library of Medicine as the source is appreciated but not required. The full RxNorm dataset requires a free license.https://www.nlm.nih.gov/research/umls/rxnorm/docs/termsofservice.htmlbethanecholhttps://rxnav.nlm.nih.gov/id/rxnorm/19257
- NORMAN Suspect List ExchangeLICENSEData: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0https://creativecommons.org/licenses/by/4.0/BETHANECHOLNORMAN Suspect List Exchange Classificationhttps://www.norman-network.com/nds/SLE/
- WHO Anatomical Therapeutic Chemical (ATC) ClassificationLICENSEUse of all or parts of the material requires reference to the WHO Collaborating Centre for Drug Statistics Methodology. Copying and distribution for commercial purposes is not allowed. Changing or manipulating the material is not allowed.https://www.whocc.no/copyright_disclaimer/
- PharmGKBLICENSEPharmGKB data are subject to the Creative Commons Attribution-ShareALike 4.0 license (https://creativecommons.org/licenses/by-sa/4.0/).https://www.pharmgkb.org/page/policiesbethanecholhttps://www.pharmgkb.org/chemical/PA448613
- PharosLICENSEData accessed from Pharos and TCRD is publicly available from the primary sources listed above. Please respect their individual licenses regarding proper use and redistribution.https://pharos.nih.gov/aboutbethanecholhttps://pharos.nih.gov/ligands/LZMDLZWYVFM7
- Wikidatabethanecholhttps://www.wikidata.org/wiki/Q419059
- WikipediaNickel arsenidehttps://en.wikipedia.org/wiki/Nickel_arsenideBethanecholhttps://en.wikipedia.org/wiki/Bethanechol
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlBethanecholhttps://www.ncbi.nlm.nih.gov/mesh/68018723Parasympathomimeticshttps://www.ncbi.nlm.nih.gov/mesh/68010277Muscarinic Agonistshttps://www.ncbi.nlm.nih.gov/mesh/68018721
- PubChem
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 390371312https://pubchem.ncbi.nlm.nih.gov/substance/390371312
- NCBI