Osteoprotegerin
PubChem CID
4378574
Structure
Molecular Formula
Synonyms
- 7-Octadecynoic acid
- octadec-7-ynoic acid
- 19220-35-0
- FDCR 1 Protein
- OSTEOPROTEGERIN
Molecular Weight
280.4 g/mol
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Dates
- Create:2005-09-14
- Modify:2025-01-11
Description
7-octadecynoic acid is a long-chain fatty acid.
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Chemical Structure Depiction
octadec-7-ynoic acid
Computed by LexiChem 2.6.6 (PubChem release 2019.06.18)
InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-10,13-17H2,1H3,(H,19,20)
Computed by InChI 1.0.5 (PubChem release 2019.06.18)
XXUPLYBCNPLTIW-UHFFFAOYSA-N
Computed by InChI 1.0.5 (PubChem release 2019.06.18)
CCCCCCCCCCC#CCCCCCC(=O)O
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)
C18H32O2
Computed by PubChem 2.1 (PubChem release 2019.06.18)
19220-35-0
- FDCR 1 Protein
- FDCR-1 Protein
- Follicular Dendritic Cell Derived Receptor 1
- Follicular Dendritic Cell-Derived Receptor-1
- OCIF Protein
- Osteoclastogenesis Inhibitory Factor
- Osteoprotegerin
- Receptors, Tumor Necrosis Factor, Member 11b
- Tumor Necrosis Factor Receptor 11b
- Tumor Necrosis Factor Receptor Superfamily, Member 11b
- 7-Octadecynoic acid
- octadec-7-ynoic acid
- 19220-35-0
- FDCR 1 Protein
- OSTEOPROTEGERIN
- OCIF Protein
- FDCR-1 Protein
- starbld0004276
- SCHEMBL3627975
- CHEMBL2397332
- DTXSID60402607
- CHEBI:196519
- Osteoclastogenesis inhibitory factor
- Tumor Necrosis Factor Receptor 11b
- LMFA01030567
- AKOS024418758
- Follicular Dendritic Cell Derived Receptor 1
- Follicular Dendritic Cell-Derived Receptor-1
- Recombinant Human Osteoprotegerin/Fc Chimera
- Receptors, Tumor Necrosis Factor, Member 11b
- tumor necrosis factor receptor superfamily, member 11b
- Osteoprotegerin/Fc Chimera from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
Property Name
Property Value
Reference
Property Name
Molecular Weight
Property Value
280.4 g/mol
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
XLogP3
Property Value
6.3
Reference
Computed by XLogP3 3.0 (PubChem release 2019.06.18)
Property Name
Hydrogen Bond Donor Count
Property Value
1
Reference
Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Property Name
Hydrogen Bond Acceptor Count
Property Value
2
Reference
Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Property Name
Rotatable Bond Count
Property Value
13
Reference
Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Property Name
Exact Mass
Property Value
280.240230259 Da
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
Monoisotopic Mass
Property Value
280.240230259 Da
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
Topological Polar Surface Area
Property Value
37.3 Ų
Reference
Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Property Name
Heavy Atom Count
Property Value
20
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
282
Reference
Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
1
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2011.04.04)
Fatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Unsaturated fatty acids [FA0103]
Follow these links to do a live 2D search or do a live 3D search for this compound, sorted by annotation score. This section is deprecated (see here for details), but these live search links provide equivalent functionality to the table that was previously shown here.
Similar Compounds (2D)
Similar Conformers (3D)
Same Count
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=XXUPLYBCNPLTIW-UHFFFAOYSA-N
- ChEBI7-octadecynoic acidhttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:196519
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.html
- EPA DSSTox7-Octadecynoic acidhttps://comptox.epa.gov/dashboard/DTXSID60402607CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- Human Metabolome Database (HMDB)LICENSEHMDB is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (HMDB) and the original publication (see the HMDB citing page). We ask that users who download significant portions of the database cite the HMDB paper in any resulting publications.http://www.hmdb.ca/citing7-Octadecynoic acidhttp://www.hmdb.ca/metabolites/HMDB0247278
- LIPID MAPSLipid Classificationhttps://www.lipidmaps.org/
- Metabolomics Workbench7-octadecynoic acidhttps://www.metabolomicsworkbench.org/data/StructureData.php?RegNo=977
- Springer Nature
- Wikidata7-Octadecynoic acidhttps://www.wikidata.org/wiki/Q82206032
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlOsteoprotegerinhttps://www.ncbi.nlm.nih.gov/mesh/68053244
- PubChem
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 389999168https://pubchem.ncbi.nlm.nih.gov/substance/389999168
CONTENTS