6alpha-Hydroxycannabidiol
PubChem CID
53357350
Structure
Molecular Formula
Synonyms
- 6alpha-hydroxycannabidiol
- 58940-28-6
- 4JT5NXL2YQ
- 6alpha-hydroxy-CBD
- 6alpha-HO-CBD
Molecular Weight
330.5 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Dates
- Create:2011-09-19
- Modify:2025-01-11
Description
6alpha-hydroxycannabidiol is a hydroxy-cannabidiol that is cannabidiol in which the 6-pro-S hydrogen of the cyclohexene ring has been replaced by a hydroxy group. It is one of the main metabolites of cannabidiol by human liver microsomes, produced by CYP2C19 and CYP3A. It has a role as a human xenobiotic metabolite. It is a hydroxy-cannabidiol, a member of resorcinols, an olefinic compound and a secondary alcohol.
Chemical Structure Depiction
2-[(1R,4S,6R)-4-hydroxy-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
Computed by Lexichem TK 2.7.0 (PubChem release 2021.10.14)
InChI=1S/C21H30O3/c1-5-6-7-8-15-10-19(23)21(20(24)11-15)17-9-14(4)18(22)12-16(17)13(2)3/h9-11,16-18,22-24H,2,5-8,12H2,1,3-4H3/t16-,17+,18-/m0/s1
Computed by InChI 1.0.6 (PubChem release 2021.10.14)
YYLPAYRRVSQJRR-KSZLIROESA-N
Computed by InChI 1.0.6 (PubChem release 2021.10.14)
CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C([C@H](C[C@H]2C(=C)C)O)C)O
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)
C21H30O3
Computed by PubChem 2.2 (PubChem release 2021.10.14)
58940-28-6
- 6alpha-hydroxycannabidiol
- 58940-28-6
- 4JT5NXL2YQ
- 6alpha-hydroxy-CBD
- 6alpha-HO-CBD
- 6alpha-OH-CBD
- 6alpha-HO-cannabidiol
- 6alpha-OH-cannabidiol
- 6alpha-hydroxy-cannabidiol
- CHEBI:133049
- 6.ALPHA.-HYDROXYCANNABIDIOL
- 2-[(1R,4S,6R)-4-hydroxy-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
- Cannabidiol metabolite (6alpha-hydroxycannabidiol)
- 1,3-Benzenediol, 2-((1R,4S,6R)-4-hydroxy-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)-5-pentyl-
- 2-((1R,4S,6R)-4-Hydroxy-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)-5-pentyl-1,3-benzenediol
- CANNABIDIOL METABOLITE (6.ALPHA.-HYDROXYCANNABIDIOL)
- (1'R,2'R,4'S)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,4',6-triol
- 1,3-BENZENEDIOL, 2-(4-HYDROXY-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL)-5-PENTYL-, (1R-(1.ALPHA.,4.BETA.,6.BETA.))-
- 1,3-Benzenediol, 2-(4-hydroxy-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)-5-pentyl-, (1R-(1alpha,4beta,6beta))-
- 1,3-Benzenediol,2-[4-hydroxy-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-,[1R-(1a,4b,6b)]-
- (?)-6?-hydroxy Cannabidiol
- UNII-4JT5NXL2YQ
- Q57829791
- (1'R,2'R,4'S)-5'-Methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,4',6-triol
- [1R-(1alpha,4beta,6beta)]-2-[4-Hydroxy-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
Property Name
Property Value
Reference
Property Name
Molecular Weight
Property Value
330.5 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
XLogP3-AA
Property Value
5.2
Reference
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Donor Count
Property Value
3
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Acceptor Count
Property Value
3
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Rotatable Bond Count
Property Value
6
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Exact Mass
Property Value
330.21949481 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Monoisotopic Mass
Property Value
330.21949481 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Topological Polar Surface Area
Property Value
60.7 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Heavy Atom Count
Property Value
24
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
444
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
3
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
1
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)
Follow these links to do a live 2D search or do a live 3D search for this compound, sorted by annotation score. This section is deprecated (see here for details), but these live search links provide equivalent functionality to the table that was previously shown here.
Same Connectivity Count
Same Parent, Connectivity Count
Similar Compounds (2D)
Similar Conformers (3D)
Same Count
- ChEBI6alpha-hydroxycannabidiolhttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:133049
- ChemIDplus6alpha-Hydroxycannabidiolhttps://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0058940286ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice2-[(1R,4S,6R)-4-hydroxy-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diolhttps://echa.europa.eu/substance-information/-/substanceinfo/100.348.847
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking6ALPHA-HYDROXYCANNABIDIOLhttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/4JT5NXL2YQ
- PharmGKBLICENSEPharmGKB data are subject to the Creative Commons Attribution-ShareALike 4.0 license (https://creativecommons.org/licenses/by-sa/4.0/).https://www.pharmgkb.org/page/policies6alpha-hydroxycannabidiolhttps://www.pharmgkb.org/chemical/PA166224246
- Wikidata6α-hydroxycannabidiolhttps://www.wikidata.org/wiki/Q57829791
- PubChem
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- NCBI
CONTENTS