Vitamin
PubChem CID
266052
Structure
Molecular Formula
Synonyms
- Laetrile
- 1332-94-1
- 6-[cyano(phenyl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
- beta-D-Glucopyranosiduronic acid, alpha-cyanobenzyl
- Vitamin
Molecular Weight
309.27 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Dates
- Create:2005-03-26
- Modify:2025-01-18
Description
Laetrile is originally, the name laetrile was the contraction of laevo-mandelonitrile glucoside, a cyanogenic glycoside found naturally in some plants. Over the years the meaning of laetrile has changed. There are now preparations called Laetrile where amygdalin is the major constituent. Laetrile and amygdalin are often used interchangeably, but are different agents. Cyanide and benzaldehyde are metabolites of both laetrile and amygdalin. Both metabolites may possess antineoplastic properties. Laetrile has been used as an anticancer treatment in humans worldwide, but scientific evidence does not support its effectiveness. It is not approved for use in the United States. (NCI04)
Vitamin is a group of organic food substances found in animals and plants in small quantities. They must be supplied in diet or dietary supplement and are essential for normal metabolism.
A cyanogenic glycoside found in the seeds of Rosaceae.
Chemical Structure Depiction
Conformer generation is disallowed since too many undefined stereo centers
6-[cyano(phenyl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Computed by Lexichem TK 2.7.0 (PubChem release 2021.10.14)
InChI=1S/C14H15NO7/c15-6-8(7-4-2-1-3-5-7)21-14-11(18)9(16)10(17)12(22-14)13(19)20/h1-5,8-12,14,16-18H,(H,19,20)
Computed by InChI 1.0.6 (PubChem release 2021.10.14)
XLSLFPQAPYONPW-UHFFFAOYSA-N
Computed by InChI 1.0.6 (PubChem release 2021.10.14)
C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)C(=O)O)O)O)O
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)
C14H15NO7
Computed by PubChem 2.2 (PubChem release 2021.10.14)
1332-94-1
- Amygdalin
- Amygdaloside
- Laetrile
- Mandelonitrile beta Gentiobioside
- Mandelonitrile-beta-Gentiobioside
- Neoamygdalin
- Vitamin B17
- Laetrile
- 1332-94-1
- 6-[cyano(phenyl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
- beta-D-Glucopyranosiduronic acid, alpha-cyanobenzyl
- Vitamin
- cyano(phenyl)methyl hexopyranosiduronic acid
- NSC103055
- NSC103055; Mandelonitrile beta-glucuronide
- DTXSID30927998
- l-Mandelonitrile-.beta.-glucuronoside
- NSC-103055
- L-Mandelonitrile-.beta.-glucuronic acid
- .beta.-D-Glucopyranosiduronic acid, (R)-
- Cyanophenylmethyl-.beta.-D-glucopyranosiduronic acid
- .beta.-D-Glucopyranosiduronic acid, .alpha.-cyanobenzyl
- beta-D-Glucopyranosiduronic acid, (R)-cyanophenylmethyl
Property Name
Property Value
Reference
Property Name
Molecular Weight
Property Value
309.27 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
XLogP3-AA
Property Value
-0.3
Reference
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Donor Count
Property Value
4
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Acceptor Count
Property Value
8
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Rotatable Bond Count
Property Value
4
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Exact Mass
Property Value
309.08485182 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Monoisotopic Mass
Property Value
309.08485182 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Topological Polar Surface Area
Property Value
140 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Heavy Atom Count
Property Value
22
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
442
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
6
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
1
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)
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Same Connectivity Count
Same Parent, Connectivity Count
Similar Compounds (2D)
Similar Conformers (3D)
Same Count
Laetrile (annotation moved to)
Drug and label
Antineoplastic Agents, Phytogenic
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- DailyMed
- DTP/NCILICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuse
- EPA DSSToxCyano(phenyl)methyl hexopyranosiduronic acidhttps://comptox.epa.gov/dashboard/DTXSID30927998
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuse
- Wikidata
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlAntineoplastic Agents, Phytogenichttps://www.ncbi.nlm.nih.gov/mesh/68000972
- PubChem
CONTENTS