Technetium tc 99m exametazime
- Tc-99m hmpao
- Ceretec (TN)
- Technetium Tc-99m exametazime
- Technetium Tc 99m exametazime (USP)
- Technetium tc 99m exametazime [USAN]
- Create:2006-11-22
- Modify:2025-01-25
- 99m-Tc-HMPAO
- 99mTc-HMPAO
- Ceretec
- Tc 99m Exametazime
- Tc 99m Hexamethylpropyleneamine Oxime
- Tc-99m HMPAO
- Tc-99m-Exametazime
- Tc-99m-Hexamethylpropyleneamine Oxime
- Technetium Tc 99m Exametazime
- Technetium Tc 99m Hexamethylpropylene amine Oxime
- Technetium Tc 99m Hexamethylpropylene-amine Oxime
- Technetium Tc 99m Hexamethylpropyleneamine Oxime
- Technetium Tc-99m Exametazime (preferred)
- Technetium TC-99M exametazime kit (has subclass)
◉ Summary of Use during Lactation
Information in this record refers to the use of technetium Tc 99m exametazime (Tc 99m-hexamethylpropyleneamine oxime; Tc 99m HPAO; Tc 99m HMPAO) as a diagnostic agent. A US Nuclear Regulatory Commission subcommittee has recommended that nursing be discontinued for 24 hours after administration of all technetium Tc 99m diagnostic products to simplify guidance recommendations, although this time interval may be longer than necessary. Other experts state that breastfeeding need not be interrupted after administration of technetium Tc 99m exametazime in doses up to 500 MBq (15 mCi) to a nursing mother. However, to follow the principle of keeping exposure "as low as reasonably achievable", some experts recommend nursing the infant just before administration of the radiopharmaceutical and interrupting breastfeeding for 3 to 6 hours after the dose, then expressing the milk completely once and discarding it. If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption. Mothers need not refrain from close contact with their infants after usual clinical doses.
For white blood cells labeled with technetium Tc 99m exametazime 180 to 400 MBq, the International Atomic Energy Agency recommends that breastfeeding should be interrupted for 12 hours.
Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level, she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.
For nursing mothers who work with Tc 99m substances in their workplace, there is no need to take any precautions other than those appropriate for general radiation protection.
◉ Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
- DailyMedTECHNETIUM TC-99M EXAMETAZIMEhttps://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=TECHNETIUM+TC-99M+EXAMETAZIME
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_useTechnetium Tc-99m exametazimehttps://www.drugbank.ca/drugs/DB09163
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- Drugs and Lactation Database (LactMed)Technetium Tc 99m Exametazimehttps://www.ncbi.nlm.nih.gov/books/n/lactmed/LM681/
- EU Clinical Trials Register
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- PubChem