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(+)-Igmesine hydrochloride

PubChem SID
252156450
Structure
(+)-Igmesine hydrochloride_small.png
Source
Tocris Bioscience
External ID
2332
Source Category

Chemical Vendors

Legacy Depositors

Version
Status
Live
Related Compounds
PubChem CID
CID 6438339 (Igmesine hydrochloride)
Component CID

CID 313 (Hydrochloric Acid)

CID 6438340 (Igmesine)

Parent CID
CID 6438340 (Igmesine)
Dates
  • Deposit:
    2015-08-06
  • Modify:
    2020-04-15
  • Available:
    2015-08-06
Description

NOTE: LEGACY RECORD. This record is no longer maintained in PubChem by the data contributor; therefore, it may contain outdated information. Read More...

Please note that the substance record is presented as provided to PubChem by the source (depositor). For standardized chemical structure and/or annotation information, please visit the summary page for CID 6438339.

1 2D Structure

Chemical Structure Depiction
(+)-Igmesine hydrochloride.png

2 Identity

2.1 Source

Tocris Bioscience

2.2 External ID

2332

2.3 Source Category

Chemical Vendors

Legacy Depositors

2.4 Depositor-Supplied Synonyms

2.5 Deposit Date

2015-08-06

2.6 Modify Date

Version 1
Version 2
Version 3
Version 4
Version 5
2020-04-15 (currently shown)

2.7 Available Date

2015-08-06

2.8 Status

Live

3 Depositor Comments

Selective sigma1 receptor ligand (KD = 19.1 nM), with little or no activity at sigma2 receptors (IC50 > 1000 nM). Inhibits the NMDA-induced increase in cGMP in a concentration-dependent manner (IC50 value is approximately 100 nM). Weak inhibitor of brain 5-HT uptake in vitro. Exhibits neuroprotective and antidepressant effects.

5 Information Sources

CONTENTS