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KB-R7943 mesylate

PubChem SID
241182266
Structure
KB-R7943 mesylate_small.png
Source
Tocris Bioscience
External ID
1244
Source Category

Chemical Vendors

Legacy Depositors

Version
Status
Live
Related Compounds
PubChem CID
CID 9823846 (2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate)
Component CID

CID 6395 (Methanesulfonic Acid)

CID 4534086 (Carbamimidothioic acid 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester)

Parent CID
CID 4534086 (Carbamimidothioic acid 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester)
Dates
  • Deposit:
    2015-02-23
  • Modify:
    2020-04-15
  • Available:
    2015-02-23
Description

NOTE: LEGACY RECORD. This record is no longer maintained in PubChem by the data contributor; therefore, it may contain outdated information. Read More...

Please note that the substance record is presented as provided to PubChem by the source (depositor). For standardized chemical structure and/or annotation information, please visit the summary page for CID 9823846.

1 2D Structure

Chemical Structure Depiction
KB-R7943 mesylate.png

2 Identity

2.1 Source

Tocris Bioscience

2.2 External ID

1244

2.3 Source Category

Chemical Vendors

Legacy Depositors

2.4 Depositor-Supplied Synonyms

2.5 Deposit Date

2015-02-23

2.6 Modify Date

Version 1
Version 2
Version 3
Version 4
Version 5
2020-04-15 (currently shown)

2.7 Available Date

2015-02-23

2.8 Status

Live

3 Depositor Comments

Potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 muM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 muM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors.

5 Information Sources

CONTENTS