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ETHYL 2,3-EPOXY-3-PHENYLPROPIONATE

Hazardous Substances DataBank Number
5404
Related PubChem Records
Related CIDs

1 Human Health Effects

1.1 Human Toxicity Excerpts (Complete)

TESTED AT 4% IN PETROLATUM, IT PRODUCED NO IRRITATION AFTER A 48-HOUR CLOSED-PATCH TEST IN 25 HUMAN SUBJECTS. A MAXIMIZATION TEST WAS CARRIED OUT ON 25 VOLUNTEERS. THE MATERIAL WAS TESTED AT A CONCENTRATION OF 4% IN PETROLATUM AND PRODUCED NO SENSITIZATION REACTIONS.
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369

2 Animal Toxicity Studies

2.1 Non-Human Toxicity Excerpts (Complete)

ETHYL PHENYLGLYCIDATE APPLIED FULL STRENGTH TO INTACT OR ABRADED RABBIT SKIN UNDER OCCLUSION WAS NOT IRRITATING.
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369

3 Environmental Standards & Regulations

3.1 FDA Requirements (Complete)

FDA 121.1164
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4 Chemical / Physical Properties

4.1 Molecular Formula

C11-H12-O3

4.2 Molecular Weight

192.23

4.3 Color / Form (Complete)

COLORLESS TO PALE-YELLOW LIQUID
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4.4 Odor

STRONG FRUITY ODOR SUGGESTIVE OF STRAWBERRY
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4.5 Taste

SWEET TASTE CORRESPONDING TO FRUITY ODOR
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4.6 Density

1.120-1.128 @ 25/25 °C
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4.7 Solubility (Complete)

1:6 IN 70% ALCOHOL; 1:1 IN 80% ALCOHOL
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

4.8 Refractive Index

INDEX OF REFRACTION: 1.5190-1.5230 (1.516-1.521) AT 20 °C
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

5 Chemical Safety & Handling

5.1 Flash Point

100 °C
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

6 Manufacturing / Use Information

6.1 Uses (Complete)

AS FRAGRANCE IN SOAPS, DETERGENTS, CREAMS, LOTIONS, PERFUME
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369
IN BERRY & CHERRY FOOD FLAVORINGS
Furia, T.E. (ed.). CRC Handbook of Food Additives. 2nd ed. Volume 2. Boca Raton, Florida: CRC Press, Inc., 1980., p. 272
FLAVORING AGENT IN GELATINS, PUDDINGS & BAKED GOODS
SRI
FLAVORING AGENT IN CANDY, ICE CREAM & BEVERAGES
SRI

6.2 Manufacturers

GIVAUDAN CORP, CHEMS DIV, CLIFTON, NJ 07014
SRI

6.3 Methods of Manufacturing (Complete)

BY THE REACTION OF BENZALDEHYDE AND THE ETHYL ESTER OF MONOCHLORACETIC ACID IN THE PRESENCE OF AN ALKALINE CONDENSING AGENT: BEDOUKIAN PZ, PERFUMERY AND FLAVORING SYNTHETICS 2ND EDITION, 297 (1967), ELSEVIER PUBLISHING COMPANY, NEW YORK.
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369
REACTION OF BENZALDEHYDE WITH ETHYL MONOCHLORACETATE IN PRESENCE OF AN ALKALINE CONDENSING AGENT; REACTION OF THE SILVER SALT OF PHENYL GLYCIDIC ACID WITH ETHYL IODIDE
SRI

6.4 General Manufacturing Information (Complete)

ASSAY: 99% MIN (98%).
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189
CONCENTRATION IN FINAL PRODUCT (%): SOAP: USUAL 0.01, MAXIMUM 0.1; DETERGENT: USUAL 0.001, MAXIMUM 0.01; CREAMS, LOTIONS: USUAL 0.01, MAXIMUM 0.05; PERFUME: USUAL 0.15, MAXIMUM 0.4.
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369
REPORTED USES: NON-ALCOHOLIC BEVERAGES 4.6 PPM, ICE CREAMS, ICES, ETC 12 PPM, CANDY 18 PPM, BAKED GOODS 20 PPM, GELATINS AND PUDDINGS 10-70 PPM.
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189
THE COUNCIL OF EUROPE (1970) INCLUDED ETHYL PHENYLGLYCIDATE IN ITS LIST OF TEMPORARILY ADMISSIBLE ARTIFICIAL FLAVORING SUBSTANCES.
Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 369
FEMA 2454
Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 189

6.5 U.S. Production (Complete)

(1979) PROBABLY GREATER THAN 4.54X10+5 GRAMS
SRI
(1981) PROBABLY GREATER THAN 4.54X10+5 GRAMS
SRI

6.6 U.S. Imports (Complete)

(1980) 6.01X10+5 GRAMS (PRINCPL CUSTMS DISTS)
SRI
(1981) 1.82X10+3 GRAMS (PRINCPL CUSTMS DISTS)
SRI

6.7 U.S. Exports (Complete)

(1979) No Data
SRI
(1981) No Data
SRI

7 Synonyms and Identifiers

Synonyms

121-39-1

ETHYL 2,3-EPOXY-3-PHENYLPROPIONATE

ETHYL ALPHA,BETA-EPOXYHYDROCINNAMATE

ETHYL ALPHA,BETA-EPOXY-ALPHA-PHENYLPROPIONATE

ETHYL PHENYLGLYCIDATE

ETHYL 3-PHENYLGLYCIDATE

GLYCIDIC ACID, 3-PHENYL-, ETHYL ESTER

OXIRANECARBOXYLIC ACID, 3-PHENYL-, ETHYL ESTER

7.1 Substance Title

8 Administrative Information

8.1 Hazardous Substances DataBank Number

5404

8.2 Last Revision Date

20030214

8.3 Update History

Complete Update on 02/14/2003, 1 field added/edited/deleted.

Complete Update on 11/08/2002, 1 field added/edited/deleted.

Complete Update on 08/06/2002, 1 field added/edited/deleted.

Complete Update on 01/14/2002, 1 field added/edited/deleted.

Complete Update on 08/09/2001, 1 field added/edited/deleted.

Complete Update on 05/15/2001, 1 field added/edited/deleted.

Complete Update on 06/12/2000, 1 field added/edited/deleted.

Complete Update on 02/08/2000, 1 field added/edited/deleted.

Complete Update on 02/02/2000, 1 field added/edited/deleted.

Complete Update on 09/21/1999, 1 field added/edited/deleted.

Complete Update on 08/27/1999, 1 field added/edited/deleted.

Complete Update on 06/03/1998, 1 field added/edited/deleted.

Complete Update on 03/08/1998, 1 field added/edited/deleted.

Complete Update on 11/01/1997, 1 field added/edited/deleted.

Complete Update on 01/30/1997, 1 field added/edited/deleted.

Complete Update on 05/14/1996, 1 field added/edited/deleted.

Complete Update on 01/29/1996, 1 field added/edited/deleted.

Complete Update on 01/05/1995, 1 field added/edited/deleted.

Complete Update on 04/04/1994, 1 field added/edited/deleted.

Field update on 01/06/1993, 1 field added/edited/deleted.

Field update on 03/06/1990, 1 field added/edited/deleted.

Complete Update on 01/15/1985

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