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tRNA 2-selenouridine synthase (Pseudomonas putida KT2440)

Protein
Encoding Gene
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-01-18
Description
Please note that tRNA 2-selenouridine synthase (Pseudomonas putida KT2440) does not have data or annotation in PubChem. However, annotations from external sources are available.
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.

1 Names and Identifiers

1.1 Synonyms

  • tRNA 2-selenouridine synthase
  • EC 2.9.1.3

1.2 Other Identifiers

1.2.1 RefSeq Accession

1.2.2 UniProt ID

1.2.3 Enzyme Commission (EC) Number

1.2.4 Wikidata

1.2.5 InterPro Protein

2 Sequence

>sp|Q88PM7|SELU_PSEPK tRNA 2-selenouridine synthase (Run BLAST)

MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGATKQARLEAWAAFAKAHPDGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVEQCDFVLVGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGIGQFVLEDEGRIVGSCTVPLELYQGMQHYPLVWLEDSFTNRVERILRDYVVNLSAEFKAVHGEEDGPRLFAERMLQSMANIYKRLGGERHQRLSEMLREALQEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARALRQPRK

3 Domains

3.1 CDD Domains

3.2 InterPro Domains

4 Biochemical Reactions

5 Literature

5.1 Consolidated References

6 Information Sources

  1. NCBI Protein
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  4. NCBI Conserved Domains (CDD)
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  5. UniProt
    LICENSE
    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  6. Wikidata
    TRNA 2-selenouridine synthase PP_0822
    https://www.wikidata.org/wiki/Q22315553
  7. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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