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Melanocyte-stimulating hormone receptor (Goeldi's marmoset)

Protein
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-01-17
Description
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.

1 Names and Identifiers

1.1 Synonyms

  • Melanocyte-stimulating hormone receptor
  • MSH-R
  • Melanocortin receptor 1
  • MC1-R

1.1.1 MeSH Entry Terms

  • MC1 Receptor
  • Melanocyte Melanocortin Receptor
  • Melanocortin Receptor 1
  • Melanocortin-1 Receptor
  • Receptor, Melanocortin-1

1.2 Other Identifiers

1.2.1 UniProt ID

1.2.2 GlyCosmos Protein

1.2.3 InterPro Protein

3 Sequence

>sp|Q864H6|MSHR_CALGO Melanocyte-stimulating hormone receptor (Run BLAST)

MPMQGAQRKLLGSLNSTPTATSNLGLAANHTGAPCLEVPIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSSMYCFICCLAVSDLLVSGSNMLETAIILLLEAGALVTRASVVQQLHNTIDVLTCSSMLCSLCFLGAIAVDRYISIFYALRYHSIMTLPRAQRAIAAIWVASVLSSTLFITYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIIRLHKRQPPAHKGFGLRGAATLTILLGIFFLCWGPFFLHLTLVVFCPQHMTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELRRTLKEVLLCSRWPGCWAEGGGDSVWPGSCVTLRGPLPP

4 Domains

4.1 CDD Domains

4.2 InterPro Domains

5 Literature

5.1 Consolidated References

5.2 NLM Curated PubMed Citations

6 Patents

7 Classification

7.1 MeSH Tree

8 Information Sources

  1. NCBI Protein
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
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    https://www.nlm.nih.gov/copyright.html
  4. GlyCosmos Glycoscience Portal
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    All copyrightable parts of the datasets in GlyCosmos are under the Creative Commons Attribution (CC BY 4.0) License.
    https://glycosmos.org/license
  5. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  6. NCBI Conserved Domains (CDD)
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  7. UniProt
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    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
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