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Erythropoietin (Golan Heights blind mole rat)

Protein
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-02-01
Description
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.

1 Names and Identifiers

1.1 Other Identifiers

1.1.1 UniProt ID

1.1.2 GlyCosmos Protein

1.1.3 InterPro Protein

2 Sequence

>sp|Q6H8T2|EPO_SPAGO Erythropoietin (Run BLAST)

MGVPDCLALPLLVTFLLLSLGLPVLGAPPRLICDSRVLERYILEAKEAENITMGCAEGPRFNENFTVPDTKVNFYAWKTMGVEEQAVEVWQGLSLLFEAILQAQAVLANSSQPSEMLQLHVDKAISGLRSLTSLLRALGAQKEAISPPDTTQVIPLRRFTVDTFCKLFRIYSNFLRGKLKLYTGEACRRGDR

3 Domains

3.1 CDD Domains

3.2 InterPro Domains

4 Literature

4.1 Consolidated References

5 Patents

6 Information Sources

  1. NCBI Protein
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. GlyCosmos Glycoscience Portal
    LICENSE
    All copyrightable parts of the datasets in GlyCosmos are under the Creative Commons Attribution (CC BY 4.0) License.
    https://glycosmos.org/license
  4. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  5. NCBI Conserved Domains (CDD)
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  6. UniProt
    LICENSE
    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
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