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Myoglobin (agile gibbon)

Protein
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-01-19
Description
Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity.

1 Names and Identifiers

1.1 Synonyms

  • Myoglobin
  • Nitrite reductase MB
  • 1.7.-.-
  • Pseudoperoxidase MB
  • 1.11.1.-

1.2 Other Identifiers

1.2.1 UniProt ID

1.2.2 Enzyme Commission (EC) Number

1.2.3 InterPro Protein

2 Sequence

>sp|P62734|MYG_HYLAG Myoglobin (Run BLAST)

MGLSDGEWQLVLNVWGKVEADIPSHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG

3 Domains

3.1 CDD Domains

3.2 InterPro Domains

4 Biochemical Reactions

5 Literature

5.1 Consolidated References

5.2 NLM Curated PubMed Citations

6 Patents

7 Classification

7.1 MeSH Tree

8 Information Sources

  1. NCBI Protein
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    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  4. NCBI Conserved Domains (CDD)
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  5. UniProt
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    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  6. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
  7. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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