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Myelin basic protein (domestic guinea pig)

Protein
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-01-18
Description
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).

1 Names and Identifiers

1.1 Synonyms

  • Myelin basic protein
  • MBP

1.1.1 MeSH Entry Terms

  • Golli-MBP2 Protein
  • Golli-MBP1 Protein
  • HOG5 Protein
  • HOG7 Protein
  • MBP2 Protein
  • MBP3 Protein
  • MBP1 Protein
  • MBP4 Protein
  • Myelin Basic Protein, 18.5 kDa Isoform
  • Myelin Basic Protein, Isoform 4
  • Myelin Basic Protein, Isoform 5
  • Myelin Basic Protein, 17.2 kDa Isoform
  • Myelin Basic Protein, Isoform 6
  • Myelin Basic Protein, 20.2 kDa Isoform
  • Myelin Basic Protein, Isoform 3
  • Myelin Basic Protein, Isoform 1
  • Myelin Basic Protein, Isoform 7
  • Myelin Basic Protein, 21.5 kDa Isoform
  • Myelin Basic Protein, Isoform 2

1.2 Other Identifiers

1.2.1 UniProt ID

1.2.2 InterPro Protein

2 Sequence

>sp|P25188|MBP_CAVPO Myelin basic protein (Run BLAST)

ASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGSDRAAPKRGSGKDSHHAARTTHYGSLPQKSQRSQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRADYKSKGFKGAHDAQGTLSKIFKLGGRDSRSGSPMARR

3 Domains

3.1 CDD Domains

3.2 InterPro Domains

4 Literature

4.1 Consolidated References

4.2 NLM Curated PubMed Citations

5 Patents

6 Classification

6.1 MeSH Tree

7 Information Sources

  1. NCBI Protein
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
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    https://www.nlm.nih.gov/copyright.html
  4. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  5. NCBI Conserved Domains (CDD)
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  6. UniProt
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    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
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