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Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)

Enzyme
Enzyme Class
Dates
  • Modify:
    2025-01-19
Description

This enzyme destabilizes the C-P bond, by forming an imine between one of its lysine residues and the carbonyl group of the substrate, thus allowing this, normally stable, bond to be broken

The mechanism is similar to that used by EC 4.1.2.13 to break a C-C bond

1 Names and Identifiers

1.1 Synonyms

  • 2-phosphonoacetylaldehyde phosphonohydrolase
  • Phosphonatase
  • Phosphonoacetylaldehyde phosphonohydrolase

2 Pathways

3 Biochemical Reactions

4 Catalytic Activity

Phosphonoacetaldehyde + H(2)O = acetaldehyde + phosphate

5 Cofactors

Mg(2+)

6 Literature

6.1 Protein-Chemical Co-Occurrences in Literature

6.2 Protein-Gene Co-Occurrences in Literature

6.3 Protein-Disease Co-Occurrences in Literature

7 Patents

7.1 Protein-Chemical Co-Occurrences in Patents

7.2 Protein-Gene Co-Occurrences in Patents

8 Information Sources

  1. ENZYME
    LICENSE
    Copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/).
    https://enzyme.expasy.org/enzyme.get
  2. PubChem
  3. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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