Protein-N(pi)-phosphohistidine--D-sorbitol phosphotransferase (EC 2.7.1.198)
- EC 2.-.-.- Transferases
- EC 2.7.-.- Transferring phosphorus-containing groups
- EC 2.7.1.- Phosphotransferases with an alcohol group as acceptor
- Modify:2025-01-20
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS)
The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it
The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9
Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency
The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate
- D-sorbitol PTS permease
- Glucitol PTS permease
- Sorbitol PTS permease
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