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Coumarin 8-geranyltransferase 1, chloroplastic (Citrus x limon)

Protein
Dates
  • Create:
    2017-04-15
  • Modify:
    2025-01-18
Description
Prenyltransferase specific for geranyl diphosphate as prenyl donor and coumarin as prenyl acceptor. Can use umbelliferone and esculetin as substrates, and with a lower activity, 5,7-dihydroxy-coumarin and 5-methoxy-7-hydroxycoumarin. No activity with 5-hydroxy-7-methoxycoumarin, bergaptol, xanthotoxol, p-coumaric acid, caffeic acid, 2,4-dihydroxycinnamic acid, kaempferol, genistein or homogentisate. No activity with dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as prenyl donors.

1 Names and Identifiers

1.1 Synonyms

  • Coumarin 8-geranyltransferase 1, chloroplastic
  • EC 2.5.1.138
  • Prenyltransferase 1
  • ClPT1
  • Umbelliferone 8-C-geranyltransferase
  • U8GT

1.2 Other Identifiers

1.2.1 UniProt ID

1.2.2 Enzyme Commission (EC) Number

1.2.3 BRENDA EC Number

1.2.4 InterPro Protein

2 Sequence

>sp|A0A077K8G3|CGT1A_CITLI Coumarin 8-geranyltransferase 1, chloroplastic (Run BLAST)

MLQMHSNSSFSPKCYYPLQHAGCVKTLQLPLTKVHGGLNRSESKNYAIKCTQSDSFYSTNKIRNNENSSSRNCKPFNKYRVAVTLQQQDCASNNEDDINSTSFRDVLLKKLHALYVFTRPFAMIGTIVGITSIAILPLQSFADLTPKYFMEFLKALLSAVLMNNYVGTVNQVADVEIDKVNKPGLPLASGDLSVGTGLAITLILSLTSLAIALSLQSPPLIFGLIVWFLLGTAYSVDLPFLRWKTNPFLAGMCMVIVFGLVYQFSFFIHFQKYVLGRPVVITRPLIFAAAIISTISAVMSLLKDIPDEDGDKQFGYQSISSKLGKENVLRLCVYALFFAYGVAVIVGASSSFQLGKLVSIIGHSTLAFLLWLRAQTVDLSNNASTFSFYLFVWKLFYGEYLLIHFLR

3 Domains

3.1 CDD Domains

3.2 InterPro Domains

4 Biochemical Reactions

5 Literature

5.1 Consolidated References

6 Patents

7 Information Sources

  1. NCBI Protein
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    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. BRENDA: Enzyme Functional Data
    LICENSE
    The usage of the BRENDA data is licensed under Creative Commons Attribution License CC BY 4.0.
    https://www.brenda-enzymes.org/license.php
  4. InterPro
    LICENSE
    All of the InterPro, Pfam, PRINTS and SFLD downloadable data provided on the InterPro website is freely available under CC0 1.0 Universal (CC0 1.0) Public Domain Dedication.
    https://www.ebi.ac.uk/interpro/about/license/
  5. NCBI Conserved Domains (CDD)
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    https://www.ncbi.nlm.nih.gov/home/about/policies/
  6. UniProt
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    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  7. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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