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Processes for the preparation of uracil derivatives

Patent
US-9382214-B2
Inventor

GALLAGHER DONALD J (US)

TREIBER LASZLO R (US)

HUGHES ROBERT MICHAEL (US)

CAMPOPIANO ONORATO (US)

WANG PENG (US)

Assignee

CHOU HELEN (US)

NEUROCRINE BIOSCIENCES INC (US)

NEUROCINE BIOSCIENCES INC (US)

Country
United States
Dates
  • Priority:
    2007/11/07
  • Grant:
    2016/07/05
Description
This web page summarizes information in PubChem about patent US-9382214-B2. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.

2 Full Text

3 Important Dates

3.1 Priority Date

2007/11/07

3.2 Filing Date

2014/06/19

3.3 Publication Date

2016/07/05

3.4 Grant Date

2016/07/05

4 Inventor

GALLAGHER DONALD J (US)

TREIBER LASZLO R (US)

HUGHES ROBERT MICHAEL (US)

CAMPOPIANO ONORATO (US)

WANG PENG (US)

ZHAO YUXIN (US)

CHOU SHINE K (US)

OUELLETTE MICHAEL ALLEN (US)

HETTINGER DONALD NICHOLAS (US)

5 Assignee

CHOU HELEN (US)

NEUROCRINE BIOSCIENCES INC (US)

NEUROCINE BIOSCIENCES INC (US)

6 Country

United States

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Linked Proteins

9 Linked Genes

10 Patent Family

11 Classification

11.1 IPC

C07D239/02 (inventive, first)

C07D239/553 (inventive)

C07D239/54 (inventive)

11.2 CPC

C07D239/553 (inventive)

A61P15/00 (inventive)

A61K9/1688

C07D239/54 (inventive, first)

A61K9/146

12 Citations

  • US-6608197-B2 (APP)
  • WO-2005007164-A1 (APP)
  • US-6872728-B2 (APP)
  • US-7056927-B2 (APP)
  • US-7176211-B2 (APP)
  • US-7179815-B2 (APP)
  • US-7229995-B2 (APP)
  • WO-2007122634-A2 (APP)
  • US-7419983-B2 (APP)
  • US-7462625-B2 (APP)
  • US-7501429-B2 (SEA)
  • Database Registry (online), Chemical Abstract Service, Columbus, Ohio, U.S.; Mar. 20, 2003, XPO02515863, retrieved from STN, Database accession No. 500114-68-1, compound rn 500114-68-1, abstract. (APP,APP)
  • Database Registry (online), Chemical Abstract Service, Columbus, Ohio, U.S.; Mar. 20, 2003, XPO02515864, retrieved from STN, Database accession No. 2008:10329, compound rn 500114-64-7, abstract. (APP,APP)
  • Felberbaum et al., "Clinical application of GnRH-antagonists," Molecular and Cellular Endocrinology 166:9-14, 2000. (APP,APP)
  • Western et al., "Efficient One-Step Suzuki Arylation of Unprotected Halonucleosides, Using Water-Soluble Palladium Catalysts," J. Org. Chem. 68(17):6767-6774, 2003. (APP,APP)
  • Xia et al., "Microwave-assisted rapid synthesis of 5-iodouracil derivatives," Huaxue Shiji 29(12):756-758, 2007. (English translation unavailable). (APP,APP)

13 Cited By

14 Similar Patents

15 Information Sources

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