An official website of the United States government

Iron oxide nanoparticles doped with copper

Patent
EP-3646889-A1
Inventor

HERRANZ RABANAL FERNANDO (ES)

FERNÁNDEZ BARAHONA IRENE (ES)

Assignee
CENTRO NAC DE INVESTIGACIONES CARDIOVASCULARES CARLOS III F S P (ES)
Country
European Patent Office
Dates
  • Priority:
    2018/10/30
Description
This web page summarizes information in PubChem about patent EP-3646889-A1. This includes chemicals mentioned, as reported by PubChem contributors, as well as other content, such as title, abstract, and International Patent Classification (IPC) codes. To read more about how this page was constructed, please visit the PubChem patents help page.

1 Abstract

In the present invention, we have found when iron oxide nanoparticles are doped with Cu (copper), a significant increase in the value of r1 is achieved (see figure 7), a value which measures the capacity of a contrast agent to provide a bright signal. "Normal" values of contrast agents for clinical use have values in the 4-6 range. In contrast, Cu-doped iron oxide nanoparticles (CuIONP), provide values of 16 mM -1 s -1 .

2 Full Text

3 Important Dates

3.1 Priority Date

2018/10/30

3.2 Filing Date

2018/10/30

3.3 Publication Date

2020/05/06

4 Inventor

HERRANZ RABANAL FERNANDO (ES)

FERNÁNDEZ BARAHONA IRENE (ES)

5 Assignee

CENTRO NAC DE INVESTIGACIONES CARDIOVASCULARES CARLOS III F S P (ES)

6 Country

European Patent Office

7 Linked Chemicals

7.1 PubChem Compounds

7.2 PubChem Substances

8 Classification

8.1 IPC

A61K49/18 (inventive, first)

8.2 CPC

A61K49/1866 (inventive, first)

9 Citations

  • EP-2980807-A1 (X) (SEA)
  • IRENE FERNÁNDEZ-BARAHONA ET AL: "Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging", ACS OMEGA, vol. 4, no. 2, 6 February 2019 (2019-02-06), pages 2719 - 2727, XP055582128, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b03004 (T) (SEA)
  • RAY M WONG ET AL: "Supplemental Data", ACSNANO, 14 March 2012 (2012-03-14), XP055162717, Retrieved from the Internet <URL:http://pubs.acs.org/doi/suppl/10.1021/nn300494k/suppl_file/nn300494k_si_001.pdf> [retrieved on 20150116] (SEA)
  • RAY M. WONG ET AL: "Rapid Size-Controlled Synthesis of Dextran-Coated, 64 Cu-Doped Iron Oxide Nanoparticles", ACS NANO, vol. 6, no. 4, 24 April 2012 (2012-04-24), pages 3461 - 3467, XP055162716, ISSN: 1936-0851, DOI: 10.1021/nn300494k (A) (SEA)
  • SHI XUDONG ET AL: "Integrin [alpha]v[beta]3receptor targeting PET/MRI dual-modal imaging probe based on the64Cu labeled manganese ferrite nanoparticles", JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER INC, US, vol. 186, 6 July 2018 (2018-07-06), pages 257 - 263, XP085434168, ISSN: 0162-0134, DOI: 10.1016/J.JINORGBIO.2018.06.004 (A) (SEA)

10 Similar Patents

11 Information Sources

  1. Google Patents
    LICENSE
    "Google Patents Research Data" by Google, based on data provided by IFI CLAIMS Patent Services and OntoChem, is licensed under a Creative Commons Attribution 4.0 International License.
    https://creativecommons.org/licenses/by/4.0/legalcode
  2. PubChem
CONTENTS