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purB - adenylosuccinate lyase (Pyrococcus horikoshii OT3)

Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-20

1 Names and Identifiers

1.1 Synonyms

PH0852

1.1.1 MeSH Entry Terms

Adenylosuccinase

1.2 Other Identifiers

1.2.1 Enzyme Commission (EC) Number

2 Proteins

2.1 Protein Function

Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

2.2 Protein Targets

3 Biochemical Reactions

4 Literature

4.1 NLM Curated PubMed Citations

4.2 Gene-Chemical Co-Occurrences in Literature

4.3 Gene-Gene Co-Occurrences in Literature

4.4 Gene-Disease Co-Occurrences in Literature

5 Patents

5.1 Gene-Chemical Co-Occurrences in Patents

5.2 Gene-Gene Co-Occurrences in Patents

5.3 Gene-Disease Co-Occurrences in Patents

6 Classification

6.1 MeSH Tree

7 Information Sources

  1. NCBI Gene
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  2. PubChem
  3. Medical Subject Headings (MeSH)
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    https://www.nlm.nih.gov/copyright.html
  4. UniProt
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    https://www.uniprot.org/help/license
  5. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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