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polybromo - polybromo (fruit fly)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-19
Description
Predicted to enable chromatin binding activity. Involved in cellular component assembly involved in morphogenesis; chromatin remodeling; and negative regulation of transcription by RNA polymerase II. Part of brahma complex. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; ganglia; and ventral nerve cord primordium. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1).

1 Names and Identifiers

1.1 Synonyms

  • BAF180
  • Bap180
  • CG11375
  • Dmel\CG11375
  • PB
  • POLYBROMO
  • Pb
  • Polybromo
  • anon-WO0140519.158
  • baf180
  • bap180
  • CG11375-PA
  • polybromo-PA

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 FlyBase ID

1.2.4 Wikidata

2 BioAssays

2.1 RNAi BioAssays

3 Interactions and Pathways

3.1 Interactions

4 Expression

5 Literature

5.1 Consolidated References

5.2 Gene-Chemical Co-Occurrences in Literature

5.3 Gene-Gene Co-Occurrences in Literature

5.4 Gene-Disease Co-Occurrences in Literature

6 Classification

6.1 Gene Ontology: Biological Process

6.2 Gene Ontology: Cellular Component

6.3 Gene Ontology: Molecular Function

7 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  4. BioGRID
    LICENSE
    The MIT License (MIT); Copyright Mike Tyers Lab
    https://wiki.thebiogrid.org/doku.php/terms_and_conditions
  5. Database of Interacting Proteins (DIP)
    LICENSE
    All DIP database records available under the terms set by the Creative Commons Attribution-NoDerivs License.
    https://dip.doe-mbi.ucla.edu/dip/termsofuse.html
  6. FlyBase
    LICENSE
    All annotations and data produced by FlyBase that are accessible from flybase.org are distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
    https://wiki.flybase.org/wiki/FlyBase:About#FlyBase_Licenses_and_Availability
  7. NCBI Gene Expression Omnibus (GEO)
  8. Wikidata
  9. Gene Ontology (GO)
    LICENSE
    Gene Ontology Consortium data and data products are licensed under the Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/legalcode)
    http://geneontology.org/docs/go-citation-policy/
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