polybromo - polybromo (fruit fly)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-19
Description
Predicted to enable chromatin binding activity. Involved in cellular component assembly involved in morphogenesis; chromatin remodeling; and negative regulation of transcription by RNA polymerase II. Part of brahma complex. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; ganglia; and ventral nerve cord primordium. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1).
- BAF180
- Bap180
- CG11375
- Dmel\CG11375
- PB
- POLYBROMO
- Pb
- Polybromo
- anon-WO0140519.158
- baf180
- bap180
- CG11375-PA
- polybromo-PA
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- PubChem
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- FlyBaseLICENSEAll annotations and data produced by FlyBase that are accessible from flybase.org are distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).https://wiki.flybase.org/wiki/FlyBase:About#FlyBase_Licenses_and_Availability
- NCBI Gene Expression Omnibus (GEO)
- Wikidata
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