An official website of the United States government

fadd - Fas (tnfrsf6)-associated via death domain (zebrafish)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2024-12-19
Description
Predicted to enable caspase binding activity and death receptor binding activity. Acts upstream of or within positive regulation of apoptotic process. Predicted to be part of CD95 death-inducing signaling complex. Is expressed in several structures, including axis; brain; germ ring; immature eye; and ventral mandibular arch. Human ortholog(s) of this gene implicated in leukemia and primary immunodeficiency disease. Orthologous to human FADD (Fas associated via death domain).

1 Names and Identifiers

1.1 Synonyms

FAS-associated death domain protein

1.1.1 MeSH Entry Terms

  • FADD Protein, Fas-Associating
  • Fas-Associating Protein FADD
  • Fas Associated Death Domain Protein
  • Fas-Associating Protein with Death Domain
  • MORT1 Protein

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 Wikidata

1.2.4 ZFIN ID

3 Interactions and Pathways

3.1 Pathways

4 Expression

5 Literature

5.1 NLM Curated PubMed Citations

5.2 Gene-Chemical Co-Occurrences in Literature

5.3 Gene-Gene Co-Occurrences in Literature

5.4 Gene-Disease Co-Occurrences in Literature

6 Patents

6.1 Gene-Chemical Co-Occurrences in Patents

6.2 Gene-Gene Co-Occurrences in Patents

6.3 Gene-Disease Co-Occurrences in Patents

7 Classification

7.1 MeSH Tree

8 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
    Fas-Associated Death Domain Protein
    https://meshb.nlm.nih.gov/record/ui?ui=D053200
  4. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  5. NCBI Gene Expression Omnibus (GEO)
  6. The Zebrafish Information Network (ZFIN)
    LICENSE
    ZFIN data and data annotations are licensed under a Creative Commons Attribution 4.0 International License
    https://zfin.atlassian.net/wiki/spaces/general/pages/1942160112/WARRANTY+AND+LIABILITY+DISCLAIMER+OWNERSHIP+AND+LIMITS+ON+USE
  7. Wikidata
CONTENTS