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dvc-1 - DNA-dependent metalloprotease dvc-1 (Caenorhabditis elegans)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-20
Description
Please note that currently there is no data available in PubChem associated with dvc-1 - DNA-dependent metalloprotease dvc-1 (Caenorhabditis elegans). However, annotations from external sources are available.
Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in DNA damage response. Located in nucleus. Is expressed widely. Human ortholog(s) of this gene implicated in Ruijs-Aalfs syndrome. Orthologous to human SPRTN (SprT-like N-terminal domain).

1 Names and Identifiers

1.1 Other Identifiers

1.1.1 Alliance Gene ID

1.1.2 Wikidata

1.1.3 WormBase ID

2 Proteins

2.1 Protein 3D Structures

2.1.1 AlphaFold Structures

Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605

3 Interactions and Pathways

3.1 Chemical-Gene Interactions

3.2 Interactions

4 Expression

5 Literature

5.1 Consolidated References

5.2 Gene-Gene Co-Occurrences in Literature

5.3 Gene-Disease Co-Occurrences in Literature

6 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  4. BioGRID
    LICENSE
    The MIT License (MIT); Copyright Mike Tyers Lab
    https://wiki.thebiogrid.org/doku.php/terms_and_conditions
  5. Comparative Toxicogenomics Database (CTD)
    LICENSE
    It is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.
    http://ctdbase.org/about/legal.jsp
  6. NCBI Gene Expression Omnibus (GEO)
  7. Wikidata
  8. WormBase
  9. AlphaFold DB
    LICENSE
    All of the data provided is freely available for both academic and commercial use under Creative Commons Attribution 4.0 (CC-BY 4.0) licence terms.
    https://alphafold.ebi.ac.uk/faq
CONTENTS