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bmp2b - bone morphogenetic protein 2b (zebrafish)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-15
Description
Enables identical protein binding activity and protein heterodimerization activity. Involved in dorsal/ventral axis specification. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and regionalization. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; digestive system; ectoderm; fin; and mesoderm. Human ortholog(s) of this gene implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Orthologous to human BMP2 (bone morphogenetic protein 2).

1 Names and Identifiers

1.1 Synonyms

  • bmp-2
  • bmp2
  • bmp2-4
  • cb670
  • swr
  • zbmp-2
  • zbmp2
  • etID309839.20
  • swirl

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 Wikidata

1.2.4 ZFIN ID

2 Interactions and Pathways

2.1 Chemical-Gene Interactions

2.2 Interactions

2.3 Pathways

3 Expression

4 Literature

4.1 Consolidated References

4.2 Gene-Chemical Co-Occurrences in Literature

4.3 Gene-Gene Co-Occurrences in Literature

4.4 Gene-Disease Co-Occurrences in Literature

5 Patents

6 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  4. BioGRID
    LICENSE
    The MIT License (MIT); Copyright Mike Tyers Lab
    https://wiki.thebiogrid.org/doku.php/terms_and_conditions
  5. Comparative Toxicogenomics Database (CTD)
    LICENSE
    It is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.
    http://ctdbase.org/about/legal.jsp
  6. NCBI Gene Expression Omnibus (GEO)
  7. The Zebrafish Information Network (ZFIN)
    LICENSE
    ZFIN data and data annotations are licensed under a Creative Commons Attribution 4.0 International License
    https://zfin.atlassian.net/wiki/spaces/general/pages/1942160112/WARRANTY+AND+LIABILITY+DISCLAIMER+OWNERSHIP+AND+LIMITS+ON+USE
  8. Wikidata
CONTENTS