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asah1b - N-acylsphingosine amidohydrolase (acid ceramidase) 1b (zebrafish)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-18
Description
Enables N-acylsphingosine amidohydrolase activity. Acts upstream of or within several processes, including collateral sprouting; glucosylceramide catabolic process; and swimming behavior. Predicted to be located in extracellular region and lysosome. Is expressed in bone tissue; brain; gill; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1).

1 Names and Identifiers

1.1 Synonyms

  • zgc:66026
  • acid ceramidase

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 Wikidata

1.2.4 ZFIN ID

2 Interactions and Pathways

2.1 Chemical-Gene Interactions

2.2 Pathways

3 Expression

4 Literature

4.1 Consolidated References

4.2 NLM Curated PubMed Citations

4.3 Gene-Chemical Co-Occurrences in Literature

4.4 Gene-Gene Co-Occurrences in Literature

4.5 Gene-Disease Co-Occurrences in Literature

5 Patents

6 Classification

6.1 MeSH Tree

7 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  4. Comparative Toxicogenomics Database (CTD)
    LICENSE
    It is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.
    http://ctdbase.org/about/legal.jsp
  5. NCBI Gene Expression Omnibus (GEO)
  6. The Zebrafish Information Network (ZFIN)
    LICENSE
    ZFIN data and data annotations are licensed under a Creative Commons Attribution 4.0 International License
    https://zfin.atlassian.net/wiki/spaces/general/pages/1942160112/WARRANTY+AND+LIABILITY+DISCLAIMER+OWNERSHIP+AND+LIMITS+ON+USE
  7. Wikidata
  8. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
CONTENTS