asah1b - N-acylsphingosine amidohydrolase (acid ceramidase) 1b (zebrafish)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Enables N-acylsphingosine amidohydrolase activity. Acts upstream of or within several processes, including collateral sprouting; glucosylceramide catabolic process; and swimming behavior. Predicted to be located in extracellular region and lysosome. Is expressed in bone tissue; brain; gill; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1).
- zgc:66026
- acid ceramidase
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