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YEH2 - sterol esterase (Saccharomyces cerevisiae S288C)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-05
Description
Enables sterol ester esterase activity. Involved in cell wall mannoprotein biosynthetic process and sterol metabolic process. Located in plasma membrane.

1 Names and Identifiers

1.1 Synonyms

1.1.1 MeSH Entry Terms

  • 15-Ketosteryl Oleate Hydrolase
  • Acylcholesterol Lipase
  • Cholesteryl Oleate Hydrolase
  • Cholesterol Ester Hydrolase
  • Cholesterylester Hydrolase
  • Cholesterol Esterase
  • Hormone-Sensitive Lipase
  • Lipase A (Lysosomal Acid Cholesterol Esterase)
  • Lipoidal Steroid Esterase
  • Lysosomal Acid Cholesterol Esterase
  • Lysosomal Acid Lipase
  • Steroid Hormone Esterase
  • Sterol Ester Acylhydrolase

1.2 Other Identifiers

1.2.1 Alliance Gene ID

1.2.2 Enzyme Commission (EC) Number

1.2.3 GlyCosmos Gene

1.2.4 SGD ID

1.2.5 VEuPathDB ID

1.2.6 Wikidata

2 Proteins

2.1 Protein Function

Mediates the hydrolysis of steryl esters. Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism.

2.2 Protein 3D Structures

2.2.1 AlphaFold Structures

Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605

2.3 Protein Targets

3 Interactions and Pathways

3.1 Interactions

3.2 Pathways

4 Biochemical Reactions

5 Expression

6 Literature

6.1 Consolidated References

6.2 NLM Curated PubMed Citations

7 Patents

8 Classification

8.1 MeSH Tree

9 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
  4. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  5. BioGRID
    LICENSE
    The MIT License (MIT); Copyright Mike Tyers Lab
    https://wiki.thebiogrid.org/doku.php/terms_and_conditions
  6. STRING: functional protein association networks
  7. GlyCosmos Glycoscience Portal
    LICENSE
    All copyrightable parts of the datasets in GlyCosmos are under the Creative Commons Attribution (CC BY 4.0) License.
    https://glycosmos.org/license
  8. NCBI Gene Expression Omnibus (GEO)
  9. Saccharomyces Genome Database (SGD)
    LICENSE
    SGD operates under the Creative Commons Attribution 4.0 International license (CC BY 4.0).
    https://sites.google.com/view/yeastgenome-help/about
  10. UniProt
    LICENSE
    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  11. VEuPathDB: The Eukaryotic Pathogen, Vector and Host Informatics Resource
    LICENSE
    All data on VEuPathDB websites are provided freely for public use.
    https://veupathdb.org/veupathdb/app/static-content/about.html
  12. Wikidata
  13. AlphaFold DB
    LICENSE
    All of the data provided is freely available for both academic and commercial use under Creative Commons Attribution 4.0 (CC-BY 4.0) licence terms.
    https://alphafold.ebi.ac.uk/faq
  14. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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