RPS17B - ribosomal 40S subunit protein S17B (Saccharomyces cerevisiae S288C)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2024-12-19
Description
Please note that currently there is no data available in PubChem associated with RPS17B - ribosomal 40S subunit protein S17B (Saccharomyces cerevisiae S288C). However, annotations from external sources are available.
Predicted to be a structural constituent of ribosome. Involved in ribosomal small subunit assembly. Predicted to be located in cytosol and ribosome. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 4. Orthologous to human RPS17 (ribosomal protein S17).
- RP51B
- RPL51B
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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