PLDALPHA3 - phospholipase D alpha 3 (thale cress)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-07
Description
member of C2-PLD subfamily. Analyses on the gene structures/sequences, overall amino acid sequences, and domain structures indicate that PLDalpha3 is most closely related to other two PLDalphas than to other PLDs. Phylogenetic analysis has not identified a true ortholog for PLDalpha3. Involved in hyperosmotic response.
- F18G18.110
- F18G18_110
- phospholipase D alpha 3
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA) (PMID: 18364466). Active with phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and phosphatidylserine (PS) as substrates (PMID: 18364466). No activity toward phosphatidylinositol (PI) or PIP2 (PMID: 18364466). Positively mediates plant responses to hyperosmotic stresses and promotes root growth, flowering, and stress avoidance (PMID: 18364466, PMID: 19704505). Not involved in the abscisic acid regulation of stomatal movement and transpirational water loss (PMID: 18364466).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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- STRING: functional protein association networks
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