ERVMER34-1 - endogenous retrovirus group MER34 member 1, envelope (human)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Predicted to be located in extracellular region and plasma membrane.
- HEMO
- envMER34
- endogenous retroviral envelope protein HEMO
- HERV-MER_4q12 provirus ancestral Env polyprotein
- Human Endogenous MEdium-Reiteration-frequency-family-34 ORF
- LP9056 protein
- endogenous MER34 (medium-reiteration-frequency-family-34) ORF
- endogenous retrovirus group MER34 member 1 Env polyprotein
- endogenous retrovirus group MER34, member 1
- human endogenous MER34 ORF
Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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