EQW00_RS07065 - thymidylate synthase (Staphylococcus epidermidis)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-21
EQW00_07070
Thymidylate Synthetase
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
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