DOHH - deoxyhypusine hydroxylase/monooxygenase (chicken)
- HLRC1
- deoxyhypusine hydroxylase
- HEAT-like (PBS lyase) repeat containing 1
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
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- PubChem
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- STRING: functional protein association networks
- Swiss Institute of Bioinformatics Bgee
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