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DOHH - deoxyhypusine hydroxylase/monooxygenase (chicken)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-19

1 Names and Identifiers

1.1 Synonyms

  • HLRC1
  • deoxyhypusine hydroxylase
  • HEAT-like (PBS lyase) repeat containing 1

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Bgee Gene ID

1.2.3 Enzyme Commission (EC) Number

1.2.4 VEuPathDB ID

3 Proteins

3.1 Protein Function

Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.

3.2 Protein Targets

4 Interactions and Pathways

4.1 Interactions

4.2 Pathways

5 Biochemical Reactions

6 Expression

7 Literature

7.1 Gene-Chemical Co-Occurrences in Literature

7.2 Gene-Gene Co-Occurrences in Literature

7.3 Gene-Disease Co-Occurrences in Literature

8 Patents

8.1 Gene-Chemical Co-Occurrences in Patents

8.2 Gene-Gene Co-Occurrences in Patents

8.3 Gene-Disease Co-Occurrences in Patents

9 Information Sources

CONTENTS